Search Results - "Gaskell, P.C"

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families by Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., Pericak-Vance, M. A.

“…The apolipoprotein E type 4 allele (APOE-ε4) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease (AD). Risk…”
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An autosomal genomic screen for dementia in an extended Amish family by Ashley-Koch, A.E., Shao, Y., Rimmler, J.B., Gaskell, P.C., Welsh-Bohmer, K.A., Jackson, C.E., Scott, W.K., Haines, J.L., Pericak-Vance, M.A.

“…Apolipoprotein E (APOE) is the only universally confirmed susceptibility gene for late-onset Alzheimer disease (LOAD), although many loci are believed to…”
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Longitudinal follow-up of late-onset Alzheimer disease families by Carney, R.M., Slifer, M.A., Lin, P.I., Gaskell, P.C., Scott, W.K., Potocky, C.F., Hulette, C.M., Welsh-Bohmer, K.A., Schmechel, D.E., Vance, J.M., Pericak-Vance, M.A.

“…Historically, data for genetic studies are collected at one time point. However, for diseases with late onset or with complex phenotypes, such as Alzheimer…”
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Neuropathological Features of Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17q21–22 (FTDP-17): Duke Family 1684 by Hulette, C M, Pericak-Vance, M A, Roses, A D, Schmechel, D E, Yamaoka, L H, Gaskell, P C, Welsh-Bohmer, K A, Crowther, R A, Spillantini, M G

“…Frontotemporal dementia with parkinsonism (FTDP-17) is an autosomal dominant disorder that presents clinically with dementia, extrapyramidal signs, and…”
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No Genetic Effect of α1-Antichymotrypsin in Alzheimer Disease by Haines, J.L., Pritchard, M.L., Saunders, A.M., Schildkraut, J.M., Growdon, J.H., Gaskell, P.C., Farrer, L.A., Auerbach, S.A., Gusella, J.F., Locke, P.A., Rosi, B.L., Yamaoka, L., Small, G.W., Conneally, P.M., Roses, A.D., Pericak-Vance, M.A.

“…Alzheimer disease (AD) is the most common neurodegenerative disorder for individuals over the age of 40. AD has a complex etiology, and it is likely that…”
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Complete Genomic Screen in Late-Onset Familial Alzheimer’s Disease by Pericak-Vance, M.A, Bass, M.L, Yamaoka, L.H, Gaskell, P.C, Scott, W.K, Terwedow, H.A, Menold, M.M, Conneally, P.M, Small, G.W, Saunders, A.M, Roses, A.D, Haines, J.L

“…Alzheimer’s disease (AD) is a complex genetic disorder. Linkage analysis has helped unravel a portion of the genetic component of AD by identifying four loci…”
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Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene by Seizinger, B R, Rouleau, G A, Ozelius, L J, Lane, A H, Faryniarz, A G, Chao, M V, Huson, S, Korf, B R, Parry, D M, Pericak-Vance, M A

“…von Recklinghausen neurofibromatosis (VRNF) is one of the most common inherited disorders affecting the human nervous system. VRNF is transmitted as an…”
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Genetic linkage studies in Alzheimer's disease families by Pericak-Vance, M A, Yamaoka, L H, Haynes, C S, Speer, M C, Haines, J L, Gaskell, P C, Hung, W Y, Clark, C M, Heyman, A L, Trofatter, J A

“…Alzheimer's disease is a devastating neurological disorder and the leading cause of dementia among the elderly. Recent studies have localized the gene for…”
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No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians by Pritchard, M.L., Saunders, A.M., Gaskell, P.C., Small, G.W., Conneally, P.M., Rosi, B., Yamaoka, L.H., Roses, A.D., Haines, J.L., Pericak-Vance, M.A.

“…The very low density lipoprotein receptor gene (VLDL-R) is a receptor for apolipoprotein-ε (APOE)-containing lipoproteins, and thus has been suggested as a…”
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No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease by Scott, W.K., Yamaoka, L.H., Locke, P.A., Rosi, B.L., Gaskell, P.C., Saunders, A.M., Conneally, P.M., Small, G.W., Farrer, L.A., Growdon, J.H., Roses, A.D., Pericak-Vance, M.A., Haines, J.L.

“…Recent reports have shown an association between an intronic polymorphism of the presenilin‐1 (PSEN1) gene and late‐onset (age at onset > 65) familial and…”
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233 Complete genomic screen in late-onset familial Alzheimer disease by Pericak-Vancel, M.A., Gaskell, P.C., Conneally, P.M., Small, G.W., Saunders, A.M., Locke, P.A., Ter-minassian, M., Pritchard, M., Ang, J., Justice, E., Haynes, C.S., Growden, J., Roses, A.D., Haines, J.L.

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Locus heterogeneity, anticipation and reduction of the chromosome 2p minimal candidate region in autosomal dominant familial spastic paraplegia by Scott, W K, Gaskell, P C, Lennon, F, Wolpert, C M, Menold, M M, Aylsworth, A S, Warner, C, Farrell, C D, Boustany, R M, Albright, S G, Boyd, E, Kingston, H M, Cumming, W J, Vance, J M, Pericak-Vance, M A

“…We examined 11 Caucasian pedigrees with autosomal dominant 'uncomplicated' familial spastic paraplegia (SPG) for linkage to the previously identified loci on…”
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Rsal RFLP for electron transport flavoprotein-beta(ETFB) by Royal, V., Alberts, M.J., Pericak-Vance, M.A., Finocchiaro, G., Bebout, J., Yamaoka, L., Hung, W.-Y., Gaskell, P.C., Roses, A.D.

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Confirmation of locus heterogeneity in the pure form of familial spastic paraplegia by Speer, M C, Kingston, H M, Boustany, R M, Gaskell, P C, Robinson, L C, Lennon, F, Wolpert, C M, Yamaoka, L H, Kahler, S G, Hogan, E L

“…Familial spastic paraplegia (FSP), characterized by progressive spasticity of the lower extremities, is in its "pure" form generally of autosomal dominant…”
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RsaI RFLP for electron transport flavoprotein-beta(ETFB) by ROYAL, V, ALBERTS, M. J, PERICAK-VANCE, M. A, FINOCCHIARO, G, BEBOUT, J, YAMAOKA, L, HUNG, W.-Y, GASKELL, P. C, ROSES, A. D

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MspI RFLP for microtubule associated protein-2 (MAP2) by Alberts, M J, Kandt, R S, Pericak-Vance, M A, Bebout, J, Speer, M C, Siddique, T S, Yamaoka, L, Hung, W Y, Gaskell, P C, Roses, A D

“…Images…”
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Mspl RFLP for microtubule associated protein-2 (MAP2) by ALBERTS, M. J, KANDT, R. S, PERICAK-VANCE, M. A, BEBOUT, J, SPEER, M. C, SIDDIQUE, T. S, YAMAOKA, L, HUNG, W.-Y, GASKELL, P. C, ROSES, A. D

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Genetic linkage studies of chromosome 17 RFLPs in von Recklinghausen neurofibromatosis (NF1) by Pericak-Vance, M A, Yamaoka, L H, Vance, J M, Small, K, Rosenwasser, G O, Gaskell, Jr, P C, Hung, W Y, Alberts, M J, Haynes, C S, Speer, M C

“…Recent localization of the gene for von Recklinghausen neurofibromatosis (NF1) to chromosome 17 has led to studies to identify additional tightly linked probes…”
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