Search Results - "Gasic, G"

Crowding-Induced Elongated Conformation of Urea-Unfolded Apoazurin: Investigating the Role of Crowder Shape in Silico by Zegarra, Fabio C, Homouz, Dirar, Gasic, Andrei G, Babel, Lucas, Kovermann, Michael, Wittung-Stafshede, Pernilla, Cheung, Margaret S

“…Here, we show by solution nuclear magnetic resonance measurements that the urea-unfolded protein apoazurin becomes elongated when the synthetic crowding agent…”
Get full text

Critical Phenomena in the Temperature-Pressure-Crowding Phase Diagram of a Protein by Gasic, Andrei G., Boob, Mayank M., Prigozhin, Maxim B., Homouz, Dirar, Daugherty, Caleb M., Gruebele, Martin, Cheung, Margaret S.

“…Inside the cell, proteins fold and perform complex functions through global structural rearrangements. For proper function, they need to be at the brink of…”
Get full text

fMRI of sensitization to angry faces by Strauss, M.M., Makris, N., Aharon, I., Vangel, M.G., Goodman, J., Kennedy, D.N., Gasic, G.P., Breiter, H.C.

“…This study examined what is communicated by facial expressions of anger and mapped the neural substrates, evaluating the motivational salience of these…”
Get full text

BDNF, relative preference, and reward circuitry responses to emotional communication by Gasic, G.P., Smoller, J.W., Perlis, R.H., Sun, M., Lee, S., Kim, B.W., Lee, M.J., Holt, D.J., Blood, A.J., Makris, N., Kennedy, D.K., Hoge, R.D., Calhoun, J., Fava, M., Gusella, J.F., Breiter, H.C.

“…Brain derived neurotrophic factor (BDNF) regulates neural development and synaptic transmission. We have tested the hypothesis that functional variation in the…”
Get full text

Impact of hydrodynamic interactions on protein folding rates depends on temperature by Zegarra, Fabio C, Homouz, Dirar, Eliaz, Yossi, Gasic, Andrei G, Cheung, Margaret S

“…We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the impact of hydrodynamic…”
Get more information

Understanding protein-complex assembly through grand canonical maximum entropy modeling by Gasic, Andrei G., Sarkar, Atrayee, Cheung, Margaret S.

“…Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein…”
Get full text

Effects of Protein Crowders and Charge on the Folding of Superoxide Dismutase 1 Variants: A Computational Study by Sarkar, Atrayee, Gasic, Andrei G., Cheung, Margaret S., Morrison, Greg

“…The neurodegenerative disease amyotrophic lateral sclerosis (ALS) is associated with the misfolding and aggregation of the metalloenzyme protein superoxide…”
Get full text

Regional, Cellular, and Ultrastructural Distribution of N-Methyl-D- Aspartate Receptor Subunit 1 in Monkey Hippocampus by Siegel, S. J., Brose, N., Janssen, W. G., Gasic, G. P., Jahn, R., Heinemann, S. F., Morrison, J. H.

“…The regional, cellular, and subcellular distributions of N-methyl-D-aspartate (NMDA) receptor subunit 1, NMDAR-1, were investigated in monkey hippocampus by…”
Get full text

A Tale of Two Desolvation Potentials: An Investigation of Protein Behavior under High Hydrostatic Pressure by Gasic, Andrei G, Cheung, Margaret S

“…Hydrostatic pressure is a common perturbation to probe the conformations of proteins. There are two common forms of pressure-dependent potentials of mean force…”
Get full text

Coagulation Factors X, Xa, and Protein S as Potent Mitogens of Cultured Aortic Smooth Muscle Cells by Gasic, Gregory P., Arenas, Carmen P., Gasic, Tatiana B., Gasic, Gabriel J.

“…Smooth muscle cells (SMCs) in the rat carotid artery leave the quiescent state and proliferate after balloon catheter injury. The precise signals responsible…”
Get full text

Towards developing principles of protein folding and dynamics in the cell by Cheung, Margaret S, Gasic, Andrei G

“…Proteins must fold and function in the immensely complex environment of a cell, i.e. the cytoplasm-this is far from the ideal test-tube setting of a dilute…”
Get more information

Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus by Trevisan, L, Fitzgerald, L W, Brose, N, Gasic, G P, Heinemann, S F, Duman, R S, Nestler, E J

“…We examined the effects of chronic ethanol exposure on the levels of N-methyl-D-aspartate receptor subunit 1 (NMDAR1) protein, an essential component of…”
Get more information

The characterization and localization of the glutamate receptor subunit GluR1 in the rat brain by Rogers, SW, Hughes, TE, Hollmann, M, Gasic, GP, Deneris, ES, Heinemann, S

“…The cloning of cDNAs that encode functional glutamate receptors makes it possible to produce antibodies that can be used as high-affinity probes for the…”
Get full text

Decreased Absolute Amygdala Volume in Cocaine Addicts by Makris, Nikos, Gasic, Gregory P., Seidman, Larry J., Goldstein, Jill M., Gastfriend, David R., Elman, Igor, Albaugh, Matthew D., Hodge, Steven M., Ziegler, David A., Sheahan, Fred S., Caviness, Verne S., Tsuang, Ming T., Kennedy, David N., Hyman, Steven E., Rosen, Bruce R., Breiter, Hans C.

“…The amygdala is instrumental to a set of brain processes that lead to cocaine consumption, including those that mediate reward and drug craving. This study…”
Get full text

To die or to sleep, perhaps to dream by Gasic, Gregory P, Nicotera, Pierluigi

“…Establishing social contacts is the raison d’être of neurons throughout their entire life span. To form and retain functional connections, neuronal…”
Get full text

Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1 by Brose, N, Gasic, G.P., Vetter, D.E., Sullivan, J.M., Heinemann, S.F.

“…In the rat central nervous system, the mRNA encoding the N-methyl-D-aspartate receptor subunit R1 is the most ubiquitously distributed among the cloned subunit…”
Get full text

Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs by Fitzgerald, LW, Deutch, AY, Gasic, G, Heinemann, SF, Nestler, EJ

“…Because glutamate is an important modulator of subcortical dopamine (DA) function, and abnormal glutamate/DA interactions may be involved in the…”
Get full text

The Future of Neuron and the Challenges for Biomedical Research in Neuroscience by Gasic, Gregory

Get full text

Molecular neurobiology of glutamate receptors by Gasic, G P, Hollmann, M

Get full text

Structure and distribution of the Notch protein in developing Drosophila by Kidd, S, Baylies, M K, Gasic, G P, Young, M W

“…Antibodies to Notch show that it is a stable, high-molecular-weight transmembrane glycoprotein, with epidermal growth factor (EGF)-like elements exposed on the…”
Get full text