Search Results - "Gasic, Andrei G"

Crowding-Induced Elongated Conformation of Urea-Unfolded Apoazurin: Investigating the Role of Crowder Shape in Silico by Zegarra, Fabio C, Homouz, Dirar, Gasic, Andrei G, Babel, Lucas, Kovermann, Michael, Wittung-Stafshede, Pernilla, Cheung, Margaret S

“…Here, we show by solution nuclear magnetic resonance measurements that the urea-unfolded protein apoazurin becomes elongated when the synthetic crowding agent…”
Get full text

Critical Phenomena in the Temperature-Pressure-Crowding Phase Diagram of a Protein by Gasic, Andrei G., Boob, Mayank M., Prigozhin, Maxim B., Homouz, Dirar, Daugherty, Caleb M., Gruebele, Martin, Cheung, Margaret S.

“…Inside the cell, proteins fold and perform complex functions through global structural rearrangements. For proper function, they need to be at the brink of…”
Get full text

Impact of hydrodynamic interactions on protein folding rates depends on temperature by Zegarra, Fabio C, Homouz, Dirar, Eliaz, Yossi, Gasic, Andrei G, Cheung, Margaret S

“…We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the impact of hydrodynamic…”
Get more information

Effects of Protein Crowders and Charge on the Folding of Superoxide Dismutase 1 Variants: A Computational Study by Sarkar, Atrayee, Gasic, Andrei G., Cheung, Margaret S., Morrison, Greg

“…The neurodegenerative disease amyotrophic lateral sclerosis (ALS) is associated with the misfolding and aggregation of the metalloenzyme protein superoxide…”
Get full text

A Tale of Two Desolvation Potentials: An Investigation of Protein Behavior under High Hydrostatic Pressure by Gasic, Andrei G, Cheung, Margaret S

“…Hydrostatic pressure is a common perturbation to probe the conformations of proteins. There are two common forms of pressure-dependent potentials of mean force…”
Get full text

Towards developing principles of protein folding and dynamics in the cell by Cheung, Margaret S, Gasic, Andrei G

“…Proteins must fold and function in the immensely complex environment of a cell, i.e. the cytoplasm-this is far from the ideal test-tube setting of a dilute…”
Get more information

Understanding protein-complex assembly through grand canonical maximum entropy modeling by Gasic, Andrei G., Sarkar, Atrayee, Cheung, Margaret S.

“…Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein…”
Get full text

Protein Structural Fluctuations at Criticality in the Temperature-Pressure-Crowding Folding Phase Diagram by Cheung, Margaret S., Gasic, Andrei G., Daugherty, Caleb

Get full text

Macromolecular Crowding Effects on Pressure-Induced Protein Folding/Unfolding by Gasic, Andrei G., Homouz, Dirar, Cheung, Margaret S.

Get full text

Elongated Denatured Conformation of Apoazurin: Crowding and Urea Interplay by Homouz, Dirar M., Zegarra, Fabio, Kovermann, Michael, Gasic, Andrei G., Babel, Lucas, Wittung-Stafshede, Pernilla E., Cheung, Margaret S.

Get full text

Investigation of Pressure-Induced Protein Unfolding with Coarse-Grained Molecular Simulation by Homouz, Dirar M., Gasic, Andrei G., Chen, Jianfa, Cheung, Margaret S.

Get full text

Understanding Protein-Complex Assembly through Grand Canonical Maximum Entropy Modeling by Gasic, Andrei G, Sarkar, Atrayee, Cheung, Margaret S

“…Phys. Rev. Research 3, 033220 (2021) Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary…”
Get full text

A Tale of Two Desolvation Potentials: An Investigation of Protein Behavior Under High Hydrostatic Pressure by Gasic, Andrei G, Cheung, Margaret S

“…Journal of Physical Chemistry B 2020 Hydrostatic pressure is a common perturbation to probe the conformations of proteins. There are two common forms of…”
Get full text

Critical phenomena in the temperature-pressure-crowding phase diagram of a protein by Gasic, Andrei G, Boob, Mayank M, Prigozhin, Maxim B, Homouz, Dirar, Daugherty, Caleb M, Gruebele, Martin, Cheung, Margaret S

“…Phys. Rev. X 9, 041035 (2019) In the cell, proteins fold and perform complex functions through global structural rearrangements. Function requires a protein to…”
Get full text

Crowding-induced Elongated Conformation of Urea-unfolded Apoazurin: Investigating the Role of Crowder Shape In Silico by Zegarra, Fabio C, Homouz, Dirar, Gasic, Andrei G, Babel, Lucas, Kovermann, Michael, Wittung-Stafshede, Pernilla, Cheung, Margaret S

“…Journal of Physical Chemistry B (2019) Here, we show by solution nuclear magnetic resonance measurements that the urea-unfolded protein apoazurin becomes…”
Get full text

The impact of hydrodynamic interactions on protein folding rates depends on temperature by Zegarra, Fabio C, Homouz, Dirar, Eliaz, Yossi, Gasic, Andrei G, Cheung, Margaret S

“…Phys. Rev. E 97, 032402 (2018) We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the…”
Get full text