Search Results - "Gashnikova, Natalya M"

Characterization of HIV-1 Epidemic in Kyrgyzstan by Sivay, Mariya V., Totmenin, Alexei V., Zyryanova, Daria P., Osipova, Irina P., Nalimova, Tatyana M., Gashnikova, Mariya P., Ivlev, Vladimir V., Meshkov, Ivan O., Chokmorova, Umut Z., Narmatova, Elmira, Motorov, Ulukbek, Akmatova, Zhyldyz, Asybalieva, Nazgul, Bekbolotov, Aybek A., Kadyrbekov, Ulan K., Maksutov, Rinat A., Gashnikova, Natalya M.

“…Kyrgyzstan has one of the highest rates of HIV-1 spread in Central Asia. In this study, we used molecular–epidemiological approaches to examine the HIV-1…”
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Spatiotemporal dynamics of HIV-1 CRF63_02A6 sub-epidemic by Sivay, Mariya V., Maksimenko, Lada V., Osipova, Irina P., Nefedova, Anastasiya A., Gashnikova, Mariya P., Zyryanova, Dariya P., Ekushov, Vasiliy E., Totmenin, Alexei V., Nalimova, Tatyana M., Ivlev, Vladimir V., Kapustin, Dmitriy V., Pozdnyakova, Larisa L., Skudarnov, Sergey E., Ostapova, Tatyana S., Yaschenko, Svetlana V., Nazarova, Olga I., Chernov, Aleksander S., Ismailova, Tatyana N., Maksutov, Rinat A., Gashnikova, Natalya M.

“…HIV-1 epidemic in Russia is one of the fastest growing in the world reaching 1.14 million people living with HIV-1 (PLWH) in 2021. Since mid-1990s, the HIV-1…”
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Catalase Activity of IgG and κκ-IgG, λλ-IgG, and κλ-IgG Subfractions in HIV-Infected Patients and Healthy Donors by Tolmacheva, Anna S, Sedykh, Sergey E, Onvumere, Margarita K, Timofeeva, Anna M, Maksimenko, Lada V, Gashnikova, Natalya M, Nevinsky, Georgy A

“…Human immunodeficiency virus (HIV) infection is associated with pronounced oxidative stress, leading to the development of various virus-associated…”
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Patterns of HIV-1 drug resistance among HIV-infected patients receiving first-line antiretroviral therapy in Novosibirsk Region, Russia by Kapustin, Dmitriy V., Nalimova, Tatiana M., Ekushov, Vasiliy E., Kriklivaya, Nadezhda P., Halikov, Maksim R., Krasnova, Elena I., Khokhlova, Natalya I., Demchenko, Svetlana V., Pozdnaykova, Larisa L., Sivay, Mariya V., Totmenin, Alexei V., Gashnikova, Mariya P., Gotfrid, Ludmila G., Maksutov, Rinat A., Gashnikova, Natalya M.

“…•HIV-related data of patients who failed first-line ART were analysed.•Suboptimal ART adherence was identified in 48.3% of study patients.•54.6% of patients…”
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Six Highly Conserved Targets of RNAi Revealed in HIV-1-Infected Patients from Russia Are Also Present in Many HIV-1 Strains Worldwide by Kretova, Olga V., Fedoseeva, Daria M., Gorbacheva, Maria A., Gashnikova, Natalya M., Gashnikova, Maria P., Melnikova, Nataliya V., Chechetkin, Vladimir R., Kravatsky, Yuri V., Tchurikov, Nickolai A.

“…RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small…”
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Identification of a novel HIV-1 circulating recombinant form CRF157_A6C in Primorsky Territory, Russia by Halikov, Maksim R., Ekushov, Vasily E., Totmenin, Alexei V., Gashnikova, Natalya M., Antonets, Mariya E., Tregubchak, Tatyana V., Skliar, Lidiia P., Solovyova, Natalia P., Gorelova, Irina S., Beniova, Svetlana N.

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HIV-1 genetic diversity in Russia: CRF63_02A1, a new HIV type 1 genetic variant spreading in Siberia by Baryshev, Pavel B, Bogachev, Vladislav V, Gashnikova, Natalya M

“…One of the factors determining a high degree of heterogeneity in the HIV population is recombination-based variation, which leads to the emergence of the virus…”
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Novel HIV-1 A6/B recombinant forms (CRF133_A6B and URF_A6/B) circulating in Krasnoyarsk region, Russia by Maksimenko, Lada V, Sivay, Mariya V, Totmenin, Alexei V, Shvalov, Alexander N, Skudarnov, Sergey E, Ostapova, Tatyana S, Yaschenko, Svetlana V, Maksutov, Rinat A, Gashnikova, Natalya M

“…•CRF133_A6B and other URF_A6/B were discovered in Russia.•Novel A6/B recombinants were identified among PWID and their sexual partners.•Novel A6/B recombinants…”
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Construction and Characterization of Infectious Molecular Clones of HIV-1 CRF63_02A6 by Zyryanova, Daria P, Totmenin, Alexei V, Bogacheva, Natalia V, Gashnikova, Natalya M

“…Currently, HIV-1 CRF63_02A6 is the prevalent genetic variant of the HIV-infected subjects in the major part of the Siberian Federal District (Russia). The…”
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HIV drug resistance among patients experiencing antiretroviral therapy failure in Russia, 2019–2021 by Sivay, Mariya V., Maksimenko, Lada V., Nalimova, Tatiana M., Nefedova, Anastasiya A., Osipova, Irina P., Kriklivaya, Nadezda P., Gashnikova, Mariya P., Ekushov, Vasiliy E., Totmenin, Alexei V., Kapustin, Dmitriy V., Pozdnyakova, Larisa L., Skudarnov, Sergey E., Ostapova, Tatyana S., Yaschenko, Svetlana V., Nazarova, Olga I., Shevchenko, Valery V., Ilyina, Elena A., Novikova, Olga A., Agafonov, Aleksander P., Gashnikova, Natalya M.

“…•Study assesses HIV DRM among individuals experiencing ART failure in Russia.•61.5% of study patients had HIV DRM detected.•38.5% of patients had no DRM point…”
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Genetic Diversity of HIV-1 in Krasnoyarsk Krai: Area with High Levels of HIV-1 Recombination in Russia by Maksyutov, Rinat А., Gashnikova, Natalya M., Bocharov, Evgeniy F., Yaschenko, Svetlana V., Ostapova, Tatyana S., Skudarnov, Sergey E., Astakhova, Ekaterina M., Gashnikova, Mariya P., Totmenin, Aleksey V., Maksimenko, Lada V., Meshkov, Ivan O.

“…More than a quarter of HIV-infected individuals registered in Russia live in Siberia. Unlike Central Russia where HIV-1 subtype A6 is predominant, in most…”
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Predominance of CRF63_02A1 and multiple patterns of unique recombinant forms of CRF63_A1 among individuals with newly diagnosed HIV-1 infection in Kemerovo Oblast, Russia by Gashnikova, Natalya M., Zyryanova, Darya P., Astakhova, Ekaterina M., Ivlev, Vladimir V., Gashnikova, Maria P., Moskaleva, Natalya V., Aikin, Sergey S., Bulatova, Tatyana N., Pustylnikov, Sergey V., Bocharov, Evgeny F., Totmenin, Aleksey V.

“…Kemerovo Oblast (KO) has had the highest rate of HIV spread in Russia since 2011. The aim of this work was to study the genetic variation of HIV-1 in Kemerovo…”
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Conserved sequences in the current strains of HIV-1 subtype A in Russia are effectively targeted by artificial RNAi in vitro by Tchurikov, Nickolai A., Fedoseeva, Daria M., Gashnikova, Natalya M., Sosin, Dmitri V., Gorbacheva, Maria A., Alembekov, Ildar R., Chechetkin, Vladimir R., Kravatsky, Yuri V., Kretova, Olga V.

“…Highly active antiretroviral therapy has greatly reduced the morbidity and mortality of AIDS. However, many of the antiretroviral drugs are toxic with…”
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Analysis of Variability in HIV-1 Subtype A Strains in Russia Suggests a Combination of Deep Sequencing and Multitarget RNA Interference for Silencing of the Virus by Kretova, Olga V, Chechetkin, Vladimir R, Fedoseeva, Daria M, Kravatsky, Yuri V, Sosin, Dmitri V, Alembekov, Ildar R, Gorbacheva, Maria A, Gashnikova, Natalya M, Tchurikov, Nickolai A

“…Any method for silencing the activity of the HIV-1 retrovirus should tackle the extremely high variability of HIV-1 sequences and mutational escape. We studied…”
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A rapid expansion of HIV-1 CRF63_02A1 among newly diagnosed HIV-infected individuals in the Tomsk Region, Russia by Gashnikova, Natalya M, Bogachev, Vladislav V, Baryshev, Pavel B, Totmenin, Alexei V, Gashnikova, Maria P, Kazachinskaya, Anastasia G, Ismailova, Tatiana N, Stepanova, Svetlana A, Chernov, Alexander S, Mikheev, Valery N

“…The prevalence of HIV infection in different Russian regions is nonuniform. In the Tomsk region (TR), 2020 HIV new infection cases were recorded in 2013, the…”
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HIV-1 Epidemiology, Genetic Diversity, and Primary Drug Resistance in the Tyumen Oblast, Russia by Totmenin, Aleksey V., Pun’ko, Olga A., Petrova, Svetlana V., Bocharov, Evgeniy F., Gashnikova, Mariya P., Astakhova, Ekaterina M., Gashnikova, Natalya M., Popkov, Alexander V.

“…Introduction. Specific molecular epidemic features of HIV infection in Tyumen Oblast (TO), Russia, were studied. Methods. The genome sequences encoding HIV-1…”
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Analysis of resistance-associated substitutions in hepatitis C virus sequences from Kyrgyzstan by Kartashov, Mikhail Yu, Svirin, Kirill A., Bekbolotov, Ajbek A., Momusheva, Kunduz T., Iskanova, Baarinisa M., Solpueva, Ajgul' S., Motorov, Ulukbek T., Narmatova, El'mira B., Krivosheina, Ekaterina I., Gladysheva, Anastasiya V., Chub, Elena V., Gashnikova, Natal'ya M.

“…Introduction. The countries of Central Asia, including Kyrgyzstan, are characterized by high prevalence and morbidity of HCV infection. Identification of HCV…”
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Assessment of the incidence of leukemia virus (BLV) in cattle in the Republic of Dagestan using PCR diagnostics by Baboshko, D. A., Elfimov, K. A., Daudova, M. G., Koychuev, Kh. G., Gapizova, Kh. F.‐K., Gashnikova, N. M.

“…   Aim.  Assessment of the incidence of leukemia virus in cattle using PCR diagnostics in herds of the Republic of Dagestan and study of the molecular genetic…”
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The relevance of using methods of molecular epidemiology of HIV to characterize territorial epidemics: Sakhalin region, Russia by Osipova, I. P., Totmenin, A. V., Bersenev, P. G., Ilyina, E. Yu, Lomakina, E. A., Gashnikova, N. M.

“…Aim . To investigate the molecular-epidemiological characteristics of the territorial distribution of HIV infection in the Sakhalin region. Materials and…”
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Genetic diversity of hepatitis C virus and the prevalence of resistance mutations to NS5A inhibitors in the Krasnoyarsk region by Ekushov, V. E., Totmenin, A. V., Gotfrid, L. G., Halikov, M. R., Minikhanova, V.-V. V., Skudarnov, S. E., Ostapova, T. S., Gashnikova, N. M.

“…To research the molecular genetic characteristics of the HCV population circulating among HIV‐infected residents of the Krasnoyarsk Territory, including…”
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