Search Results - "Garzon, Diego J"
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Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells
Published in The Journal of neuroscience (07-03-2007)“…Alzheimer's disease (AD) is a senile dementia characterized by amyloid plaques, neurofibrillary tangles, and synaptic and cell loss. The "amyloid cascade"…”
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Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease
Published in The Journal of neuroscience (22-07-2009)“…Downregulation of brain-derived neurotrophic factor (BDNF) in the cortex occurs early in the progression of Alzheimer's disease (AD). Since BDNF plays a…”
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Altered Balance of Proteolytic Isoforms of Pro–Brain-Derived Neurotrophic Factor in Autism
Published in Journal of neuropathology and experimental neurology (01-04-2012)“…ABSTRACTDefects in synaptic development and plasticity may lead to autism. Brain-derived neurotrophic factor (BDNF) plays a critical role in synaptogenesis and…”
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