Search Results - "Garziera, Marica"

Hypoxic Modulation of HLA-G Expression through the Metabolic Sensor HIF-1 in Human Cancer Cells by Garziera, Marica, Toffoli, Giuseppe, Scarabel, Lucia

“…The human leukocyte antigen-G (HLA-G) is considered an immune checkpoint molecule involved in tumor immune evasion. Hypoxia and the metabolic sensor…”
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Soluble HLA-G expression levels and HLA-G/irinotecan association in metastatic colorectal cancer treated with irinotecan-based strategy by Scarabel, Lucia, Garziera, Marica, Fortuna, Sara, Asaro, Fioretta, Toffoli, Giuseppe, Geremia, Silvano

“…We here explore the soluble Human Leukocyte Antigen-G (sHLA-G) expression level as clinical biomarker in metastatic colorectal cancer (mCRC). To this aim the…”
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Inhibition of host immune response in colorectal cancer:Human leukocyte antigen-G and beyond by Garziera, Marica, Toffoli, Giuseppe

“…Colorectal cancer(CRC)is one of the most diffuse cancers worldwide and is still a clinical burden.Increasing evidences associate CRC clinical outcome to immune…”
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Prognostic Role of Serum Antibody Immunity to p53 Oncogenic Protein in Ovarian Cancer: A Systematic Review and a Meta-Analysis by Garziera, Marica, Montico, Marcella, Bidoli, Ettore, Scalone, Simona, Sorio, Roberto, Giorda, Giorgio, Lucia, Emilio, Toffoli, Giuseppe

“…Serum p53 autoantibodies (p53-AAbs) are the product of an endogenous immune response against p53 overexpression driven by the ovarian tumour. The p53-AAbs are…”
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HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment by Garziera, Marica, Bidoli, Ettore, Cecchin, Erika, Mini, Enrico, Nobili, Stefania, Lonardi, Sara, Buonadonna, Angela, Errante, Domenico, Pella, Nicoletta, D'Andrea, Mario, De Marchi, Francesco, De Paoli, Antonino, Zanusso, Chiara, De Mattia, Elena, Tassi, Renato, Toffoli, Giuseppe

“…An important hallmark of CRC is the evasion of immune surveillance. HLA-G is a negative regulator of host's immune response. Overexpression of HLA-G protein in…”
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Strategies to optimize siRNA delivery to hepatocellular carcinoma cells by Scarabel, Lucia, Perrone, Francesca, Garziera, Marica, Farra, Rossella, Grassi, Mario, Musiani, Francesco, Russo Spena, Concetta, Salis, Barbara, De Stefano, Lucia, Toffoli, Giuseppe, Rizzolio, Flavio, Tonon, Federica, Abrami, Michela, Chiarappa, Gianluca, Pozzato, Gabriele, Forte, Giancarlo, Grassi, Gabriele, Dapas, Barbara

“…hepatocellular carcinoma (hcc) is the predominant form of primary liver cancer and the second leading cause of cancer-associated mortality worldwide. available…”
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Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness by Farra, Rossella, Musiani, Francesco, Perrone, Francesca, Čemažar, Maja, Kamenšek, Urška, Tonon, Federica, Abrami, Michela, Ručigaj, Aleš, Grassi, Mario, Pozzato, Gabriele, Bonazza, Deborah, Zanconati, Fabrizio, Forte, Giancarlo, El Boustani, Maguie, Scarabel, Lucia, Garziera, Marica, Russo Spena, Concetta, De Stefano, Lucia, Salis, Barbara, Toffoli, Giuseppe, Rizzolio, Flavio, Grassi, Gabriele, Dapas, Barbara

“…Despite the advances in anticancer therapies, their effectiveness for many human tumors is still far from being optimal. Significant improvements in treatment…”
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Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer by Garziera, Marica, Canzonieri, Vincenzo, Cannizzaro, Renato, Geremia, Silvano, Caggiari, Laura, De Zorzi, Mariangela, Maiero, Stefania, Orzes, Enrico, Perin, Tiziana, Zanussi, Stefania, De Paoli, Paolo, De Re, Valli

“…To screen and characterize germline variants for E-cadherin (CDH1) in non-hereditary gastric cancer (GC) patients and in subjects at risk of GC. 59 GCs, 59…”
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New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach by Garziera, Marica, Roncato, Rossana, Montico, Marcella, De Mattia, Elena, Gagno, Sara, Poletto, Elena, Scalone, Simona, Canzonieri, Vincenzo, Giorda, Giorgio, Sorio, Roberto, Cecchin, Erika, Toffoli, Giuseppe

“…Next-generation sequencing (NGS) technology has advanced knowledge of the genomic landscape of ovarian cancer, leading to an innovative molecular…”
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Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC) by Garziera, Marica, Cecchin, Erika, Giorda, Giorgio, Sorio, Roberto, Scalone, Simona, De Mattia, Elena, Roncato, Rossana, Gagno, Sara, Poletto, Elena, Romanato, Loredana, Ecca, Fabrizio, Canzonieri, Vincenzo, Toffoli, Giuseppe

“…Carboplatin/paclitaxel is the reference regimen in the treatment of advanced high-grade serous ovarian cancer (HGSOC) in neo-adjuvant chemotherapy (NACT)…”
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HLA-G 3′UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer by Garziera, Marica, Virdone, Saverio, De Mattia, Elena, Scarabel, Lucia, Cecchin, Erika, Polesel, Jerry, D’Andrea, Mario, Pella, Nicoletta, Buonadonna, Angela, Favaretto, Adolfo, Toffoli, Giuseppe

“…Polymorphisms in drug-metabolizing enzymes might not completely explain inter-individual differences in toxicity profiles of patients with colorectal cancer…”
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Molecular Signature in HCV-Positive Lymphomas by De Re, Valli, Caggiari, Laura, Garziera, Marica, De Zorzi, Mariangela, Repetto, Ombretta

“…Hepatitis C virus (HCV) is a positive, single-stranded RNA virus, which has been associated to different subtypes of B-cell non-Hodgkin lymphoma (B-NHL)…”
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The Genotype for DPYD Risk Variants in Patients With Colorectal Cancer and the Related Toxicity Management Costs in Clinical Practice by Toffoli, Giuseppe, Innocenti, Federico, Polesel, Jerry, De Mattia, Elena, Sartor, Franca, Dalle Fratte, Chiara, Ecca, Fabrizio, Dreussi, Eva, Palazzari, Elisa, Guardascione, Michela, Buonadonna, Angela, Foltran, Luisa, Garziera, Marica, Bignucolo, Alessia, Nobili, Stefania, Mini, Enrico, Favaretto, Adolfo, Berretta, Massimiliano, D'Andrea, Mario, De Paoli, Antonino, Roncato, Rossana, Cecchin, Erika

“…Lack of information on the clinical utility of preemptive DPYD screening before fluoropyrimidine treatment is a major barrier preventing its use in clinical…”
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A TGF-β associated genetic score to define prognosis and platinum sensitivity in advanced epithelial ovarian cancer by Gagno, Sara, Poletto, Elena, Bartoletti, Michele, Quartuccio, Luca, Romualdi, Chiara, Garziera, Marica, Scalone, Simona, Sorio, Roberto, Dreussi, Eva, Zanusso, Chiara, De Mattia, Elena, Roncato, Rossana, Cecchin, Erika, Giorda, Giorgio, De Vita, Salvatore, Dal Bo, Michele, Puglisi, Fabio, Toffoli, Giuseppe

“…Epithelial ovarian cancer (EOC) is usually diagnosed at advanced stages with highly variable clinical outcomes, even among patients with similar clinical…”
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Identification of Novel Somatic TP53 Mutations in Patients with High-Grade Serous Ovarian Cancer (HGSOC) Using Next-Generation Sequencing (NGS) by Garziera, Marica, Cecchin, Erika, Canzonieri, Vincenzo, Sorio, Roberto, Giorda, Giorgio, Scalone, Simona, De Mattia, Elena, Roncato, Rossana, Gagno, Sara, Poletto, Elena, Romanato, Loredana, Sartor, Franca, Polesel, Jerry, Toffoli, Giuseppe

“…Somatic mutations in are a hallmark of high-grade serous ovarian cancer (HGSOC), although their prognostic and predictive value as markers is not well defined…”
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HLA-G 3'UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer by Garziera, Marica, Virdone, Saverio, De Mattia, Elena, Scarabel, Lucia, Cecchin, Erika, Polesel, Jerry, D'Andrea, Mario, Pella, Nicoletta, Buonadonna, Angela, Favaretto, Adolfo, Toffoli, Giuseppe

“…Polymorphisms in drug-metabolizing enzymes might not completely explain inter-individual differences in toxicity profiles of patients with colorectal cancer…”
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Mo1577 Different Protein Expression and Genes Patterns of Helicobater Pylori in Pathological Disorders of the Gastric Mucosa by De Re, Valli, Repetto, Ombretta, Zanussi, Stefania, Garziera, Marica, Zorzi, Mariangela, Casarotto, Mariateresa, Giacomini, Sendy, Basaglia, Giancarlo, Maiero, Stefania, Toffoli, Giuseppe, Canzonieri, Vincenzo, De Paoli, Paolo, Cannizzaro, Renato

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Characterization of Antibodies Directed against the Immunoglobulin Light κ Chain Variable Chain Region (VK) of Hepatitis C Virus-Related Type-II Mixed Cryoglobulinemia and B-Cell Proliferations by De Re, Valli, Simula, Maria Paola, Pavan, Alessandro, Garziera, Marica, Marin, Dolores, Dolcetti, Riccardo, De Vita, Salvatore, Sansonno, Domenico, Geremia, Silvano, Toffoli, Giuseppe

“…Autoimmune type‐II cryoglobulinemia (II‐MC) is sustained by hepatitis C virus (HCV) infection and B‐cell (oligo)clones. This is the reason why the disease may…”
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Evaluation of the suitability of archival B ouin‐fixed paraffin‐embedded tissue specimens to proteomic investigation by Tanca, Alessandro, Addis, Maria Filippa, Simula, Maria Paola, Pagnozzi, Daniela, Biosa, Grazia, Pisanu, Salvatore, Garziera, Marica, Cannizzaro, Renato, Canzonieri, Vincenzo, De Re, Valli, Uzzau, Sergio

“…B ouin's solution has been used for over a century as a common fixative in several pathology laboratories worldwide. Therefore, a considerable number of B…”
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Prognostic Role of Serum Antibody Immunity to p53 Oncogenic Protein in Ovarian Cancer: A Systematic Review and a Meta-Analysis: e0140351 by Garziera, Marica, Montico, Marcella, Bidoli, Ettore, Scalone, Simona, Sorio, Roberto, Giorda, Giorgio, Lucia, Emilio, Toffoli, Giuseppe

“…Objective Serum p53 autoantibodies (p53-AAbs) are the product of an endogenous immune response against p53 overexpression driven by the ovarian tumour. The…”
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