Search Results - "Garzó, Tamás"

Ascorbate synthesis-dependent glutathione consumption in mouse liver by Bánhegyi, Gábor, Csala, Miklós, Braun, László, Garzó, Tamás, Mandl, József

“…Ascorbate synthesis causes glutathione consumption in the liver. Addition of gulonolactone resulted in an increase of ascorbate production in isolated murine…”
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Glutathione depletion induces glycogenolysis dependent ascorbate synthesis in isolated murine hepatocytes by Braun, László, Csala, Miklós, Poussu, Anssi, Garzó, Tamás, Mandl, József, Bánhegyi, Gábor

“…The relationship between glutathione deficiency, glycogen metabolism and ascorbate synthesis was investigated in isolated murine hepatocytes. Glutathione…”
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Ascorbic acid synthesis is stimulated by enhanced glycogenolysis in murine liver by Braun, László, Garzó, Tamás, Mandl, József, Bánhegyi, Gábor

“…Ascorbic acid synthesis was stimulated by glucagon, dibutyryl cyclic AMP, as well as phenylephrine, vasopressin or okadaic acid, in hepatocytes prepared from…”
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Latency is the major determinant of UDP-glucuronosyltransferase activity in isolated hepatocytes by Bánhegyi, Gábor, Garzó, Tamás, Fulceri, Rosella, Benedetti, Angelo, Mandl, József

“…The glucuronidation of p-nitrophenol was measured in intact, saponin- and alamethicin-treated isolated mouse hepatocytes. In saponin-permeabilized cells the…”
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Accumulation of S-D-lactoylglutathione and transient decrease of glutathione level caused by methylglyoxal load in isolated hepatocytes by Kalapos, M P, Garzó, T, Antoni, F, Mandl, J

“…Methylglyoxal is converted to D-lactic acid through a conjugation with glutathione and S-D-lactoylglutathione is an intermediate of this pathway. In isolated…”
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Endotoxin inhibits glucuronidation in the liver by Bánhegyi, Gábor, Mucha, István, Garzó, Tamás, Antoni, Ferenc, Mandl, József

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Gluconeogenesis from ascorbic acid: ascorbate recycling in isolated murine hepatocytes by Braun, László, Puskás, Ferenc, Csala, Miklós, Gyórffy, Erika, Garzó, Tamás, Mandl, József, Bánhegyi, Gábor

“…Ascorbic acid synthesis and breakdown were investigated in isolated hepatocytes prepared from fasted mice. Stimulation of gluconeogenesis by alanine or xylitol…”
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Gluconeogenic precursors stimulate acetone metabolism in isolated murine hepatocytes by Kalapos, Miklós Péter, Riba, Pál, Garzó, Tamás, Mandl, József

“…In our earlier paper (Kalapos et al., Int. J. Biochem. 26, 1069–1079, 1994) we described that the contribution of acetone to net glucose formation in isolated…”
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Endotoxin inhibits glucuronidation in the liver: An effect mediated by intercellular communication by Bánhegyi, Gábor, Mucha, István, Garzó, Tamás, Antoni, Ferenc, Mandl, József

“…Endotoxin [lipopolysaccharide (LPS) 50 μg/mL] added to the perfusion medium increased glucose production and inhibited the glucuronidation of p-nitrophenol in…”
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Increased oxidation and decreased conjugation of drugs in the liver caused by starvation. Altered metabolism of certain aromatic compounds and acetone by Mandl, József, Bánhegyi, Gabor, Kalapos, Miklós Péter, Garzó, Tamás

“…Starvation causes several changes in the various processes of biotransformation. The focus of this review is on biotransformation of various aromatic and other…”
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Glycogenolysis--and not gluconeogenesis--is the source of UDP-glucuronic acid for glucuronidation by Bánhegyi, G, Garzó, T, Antoni, F, Mandl, J

“…Differences in cofactor (NADPH and UDP-glucuronic acid) supply for various processes of biotransformation were studied by investigating the interrelations…”
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Effect of methylglyoxal on glucose formation, drug oxidation and glutathione content in isolated murine hepatocytes by Kalapos, M P, Garzó, T, Antoni, F, Mandl, J

“…The first stage in the formation of glucose from acetone involves two oxidation steps catalyzed by isozymes of the cytochrome P-450 II E1 gene subfamily;…”
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Accumulation of phenols in isolated hepatocytes after pretreatment with methylglyoxal by Kalapos, M P, Schaff, Z, Garzó, T, Antoni, F, Mandl, J

“…The effects of a single intraperitoneal injection of methylglyoxal (50-800 mg/kg body wt.) in mice were investigated in the liver after 24 h. The…”
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High amounts of glucose and insulin inhibit p-nitrophenol conjugation in mouse hepatocytes by Bánhegyi, G, Puskás, R, Garzó, T, Antoni, F, Mandl, J

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Accumulation of phenols and catechols in isolated mouse hepatocytes in starvation or after pretreatment with acetone by Bánhegyi, G, Garzó, T, Antoni, F, Mandl, J

“…Conditions leading to the accumulation of unconjugated phenols and catechols were investigated in mouse livers. The formation of unconjugated hydroxylated…”
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Cyclic AMP-dependent phosphorylation in the control of biotransformation in the liver by Bánhegyi, G, Garzó, T, Mészáros, G, Faragó, A, Antoni, F, Mandl, J

“…The possibility of a short-term cAMP-dependent regulation of mixed-function oxidation and of glucuronide formation was investigated in isolated mouse…”
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Association of thrombin, plasmin, thrombin-antithrombin III complex and plasmin-antithrombin III complex with isolated hepatocytes by Spolarics, Z, Kalapos, M P, Léránt, I, Garzó, T, Antoni, F, Mandl, J, Machovich, R

“…The interaction of thrombin, plasmin or their antithrombin III complexes with isolated mouse hepatocytes was studied. Plasmin bound to hepatocytes in a…”
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cAMP dependent inhibition of thromboxane A2, prostacyclin and PGF2 alpha synthesis in mouse hepatocytes by Mandl, J, Mucha, I, Bánhegyi, G, Mészáros, G, Faragó, A, Spolarics, Z, Machovich, R, Antoni, F, Garzó, T

“…The role of cAMP dependent regulation in thromboxane A2, prostacyclin and PGF2 alpha synthesis (measured by radioimmunoassay) was investigated in isolated…”
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Methylglyoxal and cell viability by Braun, L, Garzó, T, Riba, P, Mandl, J, Kalapos, M P

“…Methylglyoxal by depleting glutathione stores increased Trypan-blue uptake by the cells incubated in glucose, pyruvate and amino acids free medium. Only a…”
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Net glucose production from acetone in isolated murine hepatocytes. The effect of different pretreatments of mice by Kalapos, M P, Mandl, J, Bánhegyi, G, Antoni, F, Garzó, T

“…1. To evaluate the condition under which net glucose production from acetone, added as sole substrate, occurs different pretreatments of mice, in combination…”
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