Search Results - "Garyfallos, Dimitrios"

METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation by Orellana, Esteban A., Liu, Qi, Yankova, Eliza, Pirouz, Mehdi, De Braekeleer, Etienne, Zhang, Wencai, Lim, Jihoon, Aspris, Demetrios, Sendinc, Erdem, Garyfallos, Dimitrios A., Gu, Muxin, Ali, Raja, Gutierrez, Alejandro, Mikutis, Sigitas, Bernardes, Gonçalo J.L., Fischer, Eric S., Bradley, Allan, Vassiliou, George S., Slack, Frank J., Tzelepis, Konstantinos, Gregory, Richard I.

“…The emerging “epitranscriptomics” field is providing insights into the biological and pathological roles of different RNA modifications. The RNA…”
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UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs by Gozdecka, Malgorzata, Meduri, Eshwar, Mazan, Milena, Tzelepis, Konstantinos, Dudek, Monika, Knights, Andrew J., Pardo, Mercedes, Yu, Lu, Choudhary, Jyoti S., Metzakopian, Emmanouil, Iyer, Vivek, Yun, Haiyang, Park, Naomi, Varela, Ignacio, Bautista, Ruben, Collord, Grace, Dovey, Oliver, Garyfallos, Dimitrios A., De Braekeleer, Etienne, Kondo, Saki, Cooper, Jonathan, Göttgens, Berthold, Bullinger, Lars, Northcott, Paul A., Adams, David, Vassiliou, George S., Huntly, Brian J. P.

“…The histone H3 Lys27-specific demethylase UTX (or KDM6A) is targeted by loss-of-function mutations in multiple cancers. Here, we demonstrate that UTX…”
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Immunization with Genetically Modified Trypanosomes Provides Protection against Transmissible Spongiform Encephalopathies by Triller, Gianna, Garyfallos, Dimitrios A., Papavasiliou, F. Nina, Sklaviadis, Theodoros, Stavropoulos, Pete, Xanthopoulos, Konstantinos

“…Transmissible spongiform encephalopathies are incurable neurodegenerative diseases, associated with the conversion of the physiological prion protein to its…”
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Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming by Yang, Jian, Rajan, Sandeep S., Friedrich, Mathias J., Lan, Guocheng, Zou, Xiangang, Ponstingl, Hannes, Garyfallos, Dimitrios A., Liu, Pentao, Bradley, Allan, Metzakopian, Emmanouil

“…Primed epiblast stem cells (EpiSCs) can be reverted to a pluripotent embryonic stem cell (ESC)-like state by expression of single reprogramming factor. We used…”
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Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs by Gozdecka, Malgorzata, Meduri, Eshwar, Mazan, Milena, Tzelepis, Konstantinos, Dudek, Monika, Knights, Andrew J., Pardo, Mercedes, Yu, Lu, Choudhary, Jyoti S., Metzakopian, Emmanouil, Iyer, Vivek, Yun, Haiyang, Park, Naomi, Varela, Ignacio, Bautista, Ruben, Collord, Grace, Dovey, Oliver, Garyfallos, Dimitrios A., De Braekeleer, Etienne, Kondo, Saki, Cooper, Jonathan, Göttgens, Berthold, Bullinger, Lars, Northcott, Paul A., Adams, David, Vassiliou, George S., Huntly, Brian J. P.

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TRAF3 can interact with GMEB1 and modulate its anti-apoptotic function by Kotsaris, George, Kerselidou, Despoina, Koutsoubaris, Dimitrios, Constantinou, Elena, Malamas, George, Garyfallos, Dimitrios A, Iatzivassiliou, Eudoxia G

“…Abstract Background Members of Tumor Necrosis Factor (TNF) Receptor-Associated Factors (TRAFs) family interact with the cytoplasmic tails of TNF receptor…”
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SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 by Tzelepis, Konstantinos, De Braekeleer, Etienne, Aspris, Demetrios, Barbieri, Isaia, Vijayabaskar, M. S., Liu, Wen-Hsin, Gozdecka, Malgorzata, Metzakopian, Emmanouil, Toop, Hamish D., Dudek, Monika, Robson, Samuel C., Hermida-Prado, Francisco, Yang, Yu Hsuen, Babaei-Jadidi, Roya, Garyfallos, Dimitrios A., Ponstingl, Hannes, Dias, Joao M. L., Gallipoli, Paolo, Seiler, Michael, Buonamici, Silvia, Vick, Binje, Bannister, Andrew J., Rad, Roland, Prinjha, Rab K., Marioni, John C., Huntly, Brian, Batson, Jennifer, Morris, Jonathan C., Pina, Cristina, Bradley, Allan, Jeremias, Irmela, Bates, David O., Yusa, Kosuke, Kouzarides, Tony, Vassiliou, George S.

“…We recently identified the splicing kinase gene SRPK1 as a genetic vulnerability of acute myeloid leukemia (AML). Here, we show that genetic or pharmacological…”
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Functional genomic studies of cancer immune evasion using in vitro and in vivo CRISPR/Cas9 genetic screens by Garyfallos, Dimitrios, Vassiliou, George, Bradley, Allan

“…Recent advances in cancer immunology have shed light on the mechanisms that regulate the interaction of the immune system with cancer, along with the…”
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Functional Genomic Studies of Cancer Immune Evasion Using in Vitro and in Vivo Crispr/Cas9 Genetic Screens by Garyfallos, Dimitrios

“…Recent advances in cancer immunology have shed light on the mechanisms of cancer immune evasion. An accumulation of data in recent years has identified several…”
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Abstract 1158: Modulation of splicing by inhibiting the kinase SRPK1 as a novel therapeutic strategy in myeloid leukemia by Tzelepis, Konstantinos, Braekeleer, Etienne De, Seiler, Michael, Barbieri, Isaia, Robson, Sam, Yang, Yu Hsuen, Gozdecka, Malgorzata, Dudek, Monika, Collord, Grace, Dovey, Oliver M., Metzakopian, Emmanouil, Garyfallos, Dimitrios, Cooper, Jonathan L., Buonamici, Silvia, Ponstingl, Hannes, Stratton, Michael R., Bradley, Allan, Huntly, Brian J., Pina, Cristina, Kouzarides, Tony, Yusa, Kosuke, Vassiliou, George S.

“…Abstract Acute myeloid leukemia (AML) is an aggressive cancer with a poor prognosis, for which the therapeutic landscape has changed little for decades…”
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METTL1-mediated m 7 G modification of Arg-TCT tRNA drives oncogenic transformation by Orellana, Esteban A, Liu, Qi, Yankova, Eliza, Pirouz, Mehdi, De Braekeleer, Etienne, Zhang, Wencai, Lim, Jihoon, Aspris, Demetrios, Sendinc, Erdem, Garyfallos, Dimitrios A, Gu, Muxin, Ali, Raja, Gutierrez, Alejandro, Mikutis, Sigitas, Bernardes, Gonçalo J L, Fischer, Eric S, Bradley, Allan, Vassiliou, George S, Slack, Frank J, Tzelepis, Konstantinos, Gregory, Richard I

“…The emerging "epitranscriptomics" field is providing insights into the biological and pathological roles of different RNA modifications. The RNA…”
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Free floating thrombus in the right atrium causing massive pulmonary embolism by Tsarouhas, Konstantinos, Kafantaris, Ioannis, Antonakopoulos, Athanasios, Limberopoulos, Georgios, Kouzanidis, Ioannis, Vavetsi, Spiridoula, Garyfallos, Dimitrios, Konstantinou, Loizos

“…Abstract The movement of thrombi migrating from the veins of the lower limbs can give rise to pulmonary emboli within 24 hours. This is manifested as massive…”
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Free floating thrombus in the right atrium causing massive pulmonary embolism by Tsarouhas, Konstantinos, Kafantaris, Ioannis, Antonakopoulos, Athanasios, Limberopoulos, Georgios, Kouzanidis, Ioannis, Vavetsi, Spiridoula, Garyfallos, Dimitrios, Konstantinou, Loizos

“…The movement of thrombi migrating from the veins of the lower limbs can give rise to pulmonary emboli within 24 hours. This is manifested as massive pulmonary…”
Get full text