Search Results - "Gary, Sam"

Editorial for "Alterations in Resting-State MR Functional Connectivity of the Central Autonomic Network in Multiple System Atrophy and Relationship With Disease Severity" by Ye, Zezhong, Gary, Sam E

Get full text

Recent advances in the diagnosis and management of Gaucher disease by Gary, Sam E, Ryan, Emory, Steward, Alta M, Sidransky, Ellen

“…Gaucher disease, the autosomal recessive deficiency of the lysosomal enzyme glucocerebrosidase, is associated with wide phenotypic diversity including…”
Get more information

Revolutionizing Postoperative Free Flap Monitoring-The Promise of AI to Improve Health Outcomes by Ye, Zezhong, Sun, Dan, Gary, Sam E

Get full text

Immunotherapy for Pediatric Brain and Spine Tumors: Current State and Future Directions by Estevez-Ordonez, Dagoberto, Gary, Sam E, Atchley, Travis J, Maleknia, Pedram D, George, Jordan A, Laskay, Nicholas M B, Gross, Evan G, Devulapalli, Rishi K, Johnston, James M

“…Brain tumors are the most common solid tumors and the leading cause of cancer-related deaths in children. Incidence in the USA has been on the rise for the…”
Get more information

Safety and Efficacy of Intraventricular Immunovirotherapy with Oncolytic HSV-1 for CNS Cancers by Kang, Kyung-Don, Bernstock, Joshua D, Totsch, Stacie K, Gary, Sam E, Rocco, Abbey, Nan, Li, Li, Rong, Etminan, Tina, Han, Xiaosi, Beierle, Elizabeth A, Eisemann, Tanja, Wechsler-Reya, Robert J, Bae, Sejong, Whitley, Richard, Gillespie, G Yancey, Markert, James M, Friedman, Gregory K

“…Oncolytic virotherapy with herpes simplex virus-1 (HSV) has shown promise for the treatment of pediatric and adult brain tumors; however, completed and ongoing…”
Get full text

Diffusion Histology Imaging Combining Diffusion Basis Spectrum Imaging (DBSI) and Machine Learning Improves Detection and Classification of Glioblastoma Pathology by Ye, Zezhong, Price, Richard L, Liu, Xiran, Lin, Joshua, Yang, Qingsong, Sun, Peng, Wu, Anthony T, Wang, Liang, Han, Rowland H, Song, Chunyu, Yang, Ruimeng, Gary, Sam E, Mao, Diane D, Wallendorf, Michael, Campian, Jian L, Li, Jr-Shin, Dahiya, Sonika, Kim, Albert H, Song, Sheng-Kwei

“…Glioblastoma (GBM) is one of the deadliest cancers with no cure. While conventional MRI has been widely adopted to examine GBM clinically, accurate…”
Get full text

Targeting oncometabolism to maximize immunotherapy in malignant brain tumors by Bernstock, Joshua D., Kang, Kyung-Don, Klinger, Neil V., Olsen, Hannah E., Gary, Sam, Totsch, Stacie K., Ghajar-Rahimi, Gelare, Segar, David, Thompson, Eric M., Darley-Usmar, Victor, Mott, Bryan T., Peruzzotti-Jametti, Luca, Friedman, Gregory K.

“…Brain tumors result in significant morbidity and mortality in both children and adults. Recent data indicate that immunotherapies may offer a survival benefit…”
Get full text

MRI-based assessment of function and dysfunction in myelinated axons by Spees, William M., Lin, Tsen-Hsuan, Sun, Peng, Song, Chunyu, George, Ajit, Gary, Sam E., Yang, Hsin-Chieh, Song, Sheng-Kwei

“…Repetitive electrical activity produces microstructural alteration in myelinated axons, which may afford the opportunity to non-invasively monitor function of…”
Get full text

The Impact of Peer-Led Learning Groups on First-Year Medical Students by Gary, Sam E., Chang, Samuel F., Quinn, Colin H., Baños, James, Hubner, Brook

“…Active learning and peer instruction contribute to positive learning outcomes. We developed a 25-week, question-based program for first-year medical students…”
Get full text

Signature reversion of three disease‐associated gene signatures prioritizes cancer drug repurposing candidates by Fisher, Jennifer L., Wilk, Elizabeth J., Oza, Vishal H., Gary, Sam E., Howton, Timothy C., Flanary, Victoria L., Clark, Amanda D., Hjelmeland, Anita B., Lasseigne, Brittany N.

“…Drug repurposing is promising because approving a drug for a new indication requires fewer resources than approving a new drug. Signature reversion detects…”
Get full text

The impact of edema and fiber crossing on diffusion MRI metrics assessed in an ex vivo nerve phantom: Multi‐tensor model vs. diffusion orientation distribution function by Ye, Zezhong, Gary, Sam E., Sun, Peng, Mustafi, Sourajit Mitra, Glenn, George Russell, Yeh, Fang‐Cheng, Merisaari, Harri, Song, Chunyu, Yang, Ruimeng, Huang, Guo‐Shu, Kao, Hung‐Wen, Lin, Chien‐Yuan, Wu, Yu‐Chien, Jensen, Jens H., Song, Sheng‐Kwei

“…Diffusion tensor imaging (DTI) has been employed for over 2 decades to noninvasively quantify central nervous system diseases/injuries. However, DTI is an…”
Get full text

Temozolomide and the PARP Inhibitor Niraparib Enhance Expression of Natural Killer Group 2D Ligand ULBP1 and Gamma-Delta T Cell Cytotoxicity in Glioblastoma by Jones, Amber B, Tuy, Kaysaw, Hawkins, Cyntanna C, Quinn, Colin H, Saad, Joelle, Gary, Sam E, Beierle, Elizabeth A, Ding, Lei, Rochlin, Kate M, Lamb, Lawrence S, Hjelmeland, Anita B

“…Glioblastoma (GBM) is an immunologically cold tumor, but several immunotherapy-based strategies show promise, including the administration of ex vivo expanded…”
Get full text

Standard clinical approaches and emerging modalities for glioblastoma imaging by Bernstock, Joshua D, Gary, Sam E, Klinger, Neil, Valdes, Pablo A, Ibn Essayed, Walid, Olsen, Hannah E, Chagoya, Gustavo, Elsayed, Galal, Yamashita, Daisuke, Schuss, Patrick, Gessler, Florian A, Paolo Peruzzi, Pier, Bag, Asim K, Friedman, Gregory K

“…Abstract Glioblastoma (GBM) is the most common primary adult intracranial malignancy and carries a dismal prognosis despite an aggressive multimodal treatment…”
Get full text

EXTH-75. IMMUNOVIROTHERAPY WITH PP2A AND PD-1 INHIBITION IN PEDIATRIC HIGH-GRADE GLIOMA by Kang, Kyung-Don, Frederico, Stephen, Fan, Aaron, Gary, Sam, Zhang, Zhuo, Zhou, Li, Markert, James, Bernstock, Joshua, Friedman, Gregory

“…Pediatric high-grade gliomas (HGGs) represent a significant clinical challenge with poor survival rates. Engineered oncolytic herpes simplex virus (oHSV) has…”
Get full text

EXTH-12. CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1 MEDIATES ONCOLYTIC HERPES SIMPLEX VIRUS-1 EFFICACY IN HIGH-GRADE GLIOMA by Gary, Sam, Laufer, Vincent, Tuy, Kaysaw, Kang, Kyung-Don, Oliva, Claudia, Griguer, Corinne, Hjelmeland, Anita, Friedman, Gregory

Get full text

Clinical advances in oncolytic virotherapy for pediatric brain tumors by Ghajar-Rahimi, Gelare, Kang, Kyung-Don, Totsch, Stacie K., Gary, Sam, Rocco, Abbey, Blitz, Sarah, Kachurak, Kara, Chambers, M.R., Li, Rong, Beierle, Elizabeth A., Bag, Asim, Johnston, James M., Markert, James M., Bernstock, Joshua D., Friedman, Gregory K.

“…Malignant brain tumors constitute nearly one-third of cancer diagnoses in children and have recently surpassed hematologic malignancies as the most lethal…”
Get full text

A 3’-UTR variant in SCARB2 modulates LIMP2 in patients with Gaucher disease and myoclonic epilepsy by Do, Jenny, Gary, Sam, Stubblefield, Barbara, Ryan, Emory, Lopez, Grisel, Sidransky, Ellen, Tayebi, Nahid

Get full text

IMMU-19. COMBINATION IMMUNOTHERAPY SEQUENCE MATTERS: VACCINE PRIOR TO ONCOLYTIC HSV VIROTHERAPY ENHANCES TUMOR-SPECIFIC T CELL RESPONSES AND EFFICACY by Kang, Kyung-Don, Totsch, Stacie K, Ishizuka, Andrew S, Gary, Sam E, Rocco, Abbey, Fan, Aaron, Zhou, Li, Valdes, Pablo A, Lee, SeungHo, Li, Jason, Peruzzotti-Jametti, Luca, Blitz, Sarah, Garliss, Christopher M, Johnston, James M, Markert, James M, Lynn, Geoffrey M, Bernstock, Joshua D, Friedman, Gregory K

Get full text

Mouse macrophage model of Gaucher disease for evaluating non-inhibitory chaperone candidates by Gary, Sam E., Aflaki, Elma, Berhe, Bahafta, Ory, Daniel, Sidransky, Ellen

Get full text

EPCT-22 SAFETY AND EFFICACY OF INTRAVENTRICULAR IMMUNOVIROTHERAPY WITH ONCOLYTIC HSV-1 G207 FOR TREATMENT OF LEPTOMENINGEAL DISEASE by Kang, Kyung-Don, Bernstock, Joshua, Mott, Bryan, Nan, Li, Li, Rong, Totsch, Stacie, Gary, Sam, Ghajar-Rahimi, Gelare, Etminan, Tina, Eisemann, Tanja, Wechsler-Reya, Robert, Beierle, Elizabeth, Gillespie, George, Markert, James, Friedman, Gregory

“…Leptomeningeal metastatic disease (LMD) occurs in 30–50% of newly diagnosed and recurrent pediatric malignant cerebellar tumors and 20–45% of malignant…”
Get full text