Search Results - "Garvey, Mark I."

The Efflux Pump Inhibitor Reserpine Selects Multidrug-Resistant Streptococcus pneumoniae Strains That Overexpress the ABC Transporters PatA and PatB by GARVEY, Mark I, PIDDOCK, Laura J. V

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Can a toxin gene NAAT be used to predict toxin EIA and the severity of Clostridium difficile infection? by Garvey, Mark I, Bradley, Craig W, Wilkinson, Martyn A C, Holden, Elisabeth

“…Diagnosis of infection (CDI) is controversial because of the many laboratory methods available and their lack of ability to distinguish between carriage, mild…”
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Overexpression of patA and patB, Which Encode ABC Transporters, Is Associated with Fluoroquinolone Resistance in Clinical Isolates of Streptococcus pneumoniae by GARVEY, Mark I, BAYLAY, Alison J, WONG, Ryan L, PIDDOCK, Laura J. V

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Wiping out MRSA: effect of introducing a universal disinfection wipe in a large UK teaching hospital by Garvey, Mark I, Wilkinson, Martyn A C, Bradley, Craig W, Holden, Kerry L, Holden, Elisabeth

“…Contamination of the inanimate environment around patients constitutes an important reservoir of MRSA. Here we describe the effect of introducing a universal…”
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Impact of a PCR point of care test for influenza A/B on an acute medical unit in a large UK teaching hospital: results of an observational, pre and post intervention study by Garvey, Mark I, Wilkinson, Martyn A C, Bradley, Craig W, Biggs, Martin, Reddy-Kolanu, Vinay, Osman, Husam, Carmalt, Sarah, Holden, Elisabeth

“…Influenza viruses is a leading cause of acute respiratory infection, placing a significant burden on healthcare. To reduce hospital transmission, patients…”
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The value of the infection prevention and control nurse led MRSA ward round by Garvey, Mark I, Bradley, Craig W, Wilkinson, Martyn A C, Holden, Kerry L, Clewer, Victoria, Holden, Elisabeth

“…Meticillin-resistant (MRSA) is prevalent in most parts of the world. The study took place at Queen Elizabeth Hospital Birmingham (QEHB) a UK tertiary referral…”
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Waterborne Pseudomonas aeruginosa transmission in a hematology unit? by Garvey, Mark I., Bradley, Craig W., Holden, Elisabeth

“…Pseudomonas aeruginosa is an important nosocomial pathogen that commonly colonizes hospital water supplies, including in taps and sinks. We report the…”
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Decontamination of an Extracorporeal Membrane Oxygenator Contaminated With Mycobacterium chimaera by Garvey, Mark I, Phillips, Natalie, Bradley, Craig W, Holden, Elisabeth

“…Water samples taken from extracorporeal membrane oxygenator (ECMO) devices used at University Hospitals Birmingham yielded high total viable counts (TVCs)…”
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Early observations on the impact of a healthcare worker COVID-19 vaccination programme at a major UK tertiary centre by Garvey, Mark I., Wilkinson, Martyn A C, Holden, Elisabeth, Shields, Adrian, Robertson, Alastair, Richter, Alex, Ball, Simon

“…•The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the rapid development of multiple vaccines which have been rolled out…”
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A Year in the Life of a Contaminated Heater-Cooler Unit With Mycobacterium chimaera? by Garvey, Mark I, Bradley, Craig W, Walker, Jimmy

“…OBJECTIVE Heater-cooler units (HCUs) have been shown to be a source of Mycobacterium chimaera infections. For the past year, weekly water samples have been…”
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pQEB1: a hospital outbreak plasmid lineage carrying bla KPC-2 by Moran, Robert A, Behruznia, Mahboobeh, Holden, Elisabeth, Garvey, Mark I, McNally, Alan

“…While conducting genomic surveillance of carbapenemase-producing (CPE) from patient colonisation and clinical infections at Birmingham's Queen Elizabeth…”
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Observations of SARS-CoV-2 variant of concern B.1.1.7 at the UK's largest hospital trust by Garvey, Mark I., McMurray, Claire, Casey, Anna L, Ratcliffe, Liz, Stockton, Joanne, Wilkinson, Martyn A C, Holden, Elisabeth, Osman, Husam, Loman, Nick J

“…•SARS-CoV-2 variant of concern B.1.1.7, with increased transmissibility, was identified in the UK in October 2020.•We report our observations of B.1.1.7 in…”
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Details of SARS-CoV-2 reinfections at a major UK tertiary centre by Garvey, Mark I., Casey, Anna L., Wilkinson, Martyn A.C., Ratcliffe, Liz, McMurray, Claire, Stockton, Joanne, Holden, Elisabeth, Osman, Husam, Loman, Nick J

“…•There remains uncertainty surrounding reinfection with SARS-CoV-2.•The ‘second wave’ of transmission in the UK offered an opportunity to examine this.•We…”
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Mouth care matters – A HAP prevention strategy by Garvey, Mark I., Wilkinson, Martyn A.C., Woodall, Helen, Smith, Caroline, Holden, Kerry, Cartin, Jenna, Dosanjh, Davinder, Holden, Elisabeth, Kiernan, Martin

“…•Hospital acquired pneumonia (HAP) is the most prevalent healthcare associated infection in the UK, placing a significant burden on healthcare with an…”
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Engineering waterborne Pseudomonas aeruginosa out of a critical care unit by Garvey, Mark I., Bradley, Craig W., Wilkinson, Martyn A.C., Bradley, Christina, Holden, Elisabeth

“…To describe engineering and holistic interventions on water outlets contaminated with Pseudomonas aeruginosa and the observed impact on clinical P. aeruginosa…”
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Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria by Garvey, Mark I, Rahman, M. Mukhlesur, Gibbons, Simon, Piddock, Laura J.V

“…Abstract It was hypothesised that extracts from plants that are used as herbal medicinal products contain inhibitors of efflux in Gram-negative bacteria…”
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The Effect of Universal Decolonization With Screening in Critical Care to Reduce MRSA Across an Entire Hospital by Bradley, Craig W, Wilkinson, Martyn A C, Garvey, Mark I

“…OBJECTIVE To describe the effect of universal methicillin-resistant Staphylococcus aureus (MRSA) decolonization therapy in a large intensive care unit (ICU) on…”
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Natural and synthetic compounds such as trimethoprim behave as inhibitors of efflux in Gram-negative bacteria by Piddock, Laura J. V., Garvey, Mark I., Rahman, M. Mukhlesur, Gibbons, Simon

“…Objectives We hypothesized that small heterocyclic or nitrogen-containing compounds could act as RND efflux pump inhibitors (EPIs). To ascertain possible EPIs,…”
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Reduction in methicillin-resistant Staphylococcus aureus colonisation: impact of a screening and decolonisation programme by Garvey, Mark I, Winfield, Jodie, Wiley, Carolyn, Reid, Matthew, Cooper, Mike

“…Patients in care homes are often at ‘high risk’ of being methicillin-resistant Staphylococcus aureus (MRSA) colonised. Here we report the prevalence of MRSA,…”
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Outbreak of clonal complex 22 Panton–Valentine leucocidin-positive methicillin-resistant Staphylococcus aureus by Garvey, Mark I., Bradley, Craig W., Holden, Kerry L., Oppenheim, Beryl

“…Aims: We describe the investigation and control of a nosocomial outbreak of Sequence Type (ST) 22 MRSA containing the Panton–Valentine leucocidin (PVL) toxin…”
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