Search Results - "Garvalov, Boyan K"

Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body by Pan, Chenchen, Schoppe, Oliver, Parra-Damas, Arnaldo, Cai, Ruiyao, Todorov, Mihail Ivilinov, Gondi, Gabor, von Neubeck, Bettina, Böğürcü-Seidel, Nuray, Seidel, Sascha, Sleiman, Katia, Veltkamp, Christian, Förstera, Benjamin, Mai, Hongcheng, Rong, Zhouyi, Trompak, Omelyan, Ghasemigharagoz, Alireza, Reimer, Madita Alice, Cuesta, Angel M., Coronel, Javier, Jeremias, Irmela, Saur, Dieter, Acker-Palmer, Amparo, Acker, Till, Garvalov, Boyan K., Menze, Bjoern, Zeidler, Reinhard, Ertürk, Ali

“…Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therapeutic antibodies within the entire body has long been needed…”
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ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain by Flynn, Kevin C., Hellal, Farida, Neukirchen, Dorothee, Jacob, Sonja, Tahirovic, Sabina, Dupraz, Sebastian, Stern, Sina, Garvalov, Boyan K., Gurniak, Christine, Shaw, Alisa E., Meyn, Liane, Wedlich-Söldner, Roland, Bamburg, James R., Small, J. Victor, Witke, Walter, Bradke, Frank

“…Neurites are the characteristic structural element of neurons that will initiate brain connectivity and elaborate information. Early in development, neurons…”
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Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma by Filatova, Alina, Seidel, Sascha, Böğürcü, Nuray, Gräf, Sabine, Garvalov, Boyan K, Acker, Till

“…Hypoxia is a common feature of solid tumors, which controls multiple aspects of cancer progression. One important function of hypoxia and the hypoxia-inducible…”
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Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis by Schreiber, Caroline, Gruber, Annette, Roßwag, Sven, Saraswati, Supriya, Harkins, Shannon, Thiele, Wilko, Foroushani, Zahra Hajian, Munding, Natalie, Schmaus, Anja, Rothley, Melanie, Dimmler, Arno, Tanaka, Motomu, Garvalov, Boyan K., Sleeman, Jonathan P.

“…ASAP1 is a multi-domain adaptor protein that regulates cytoskeletal dynamics, receptor recycling and intracellular vesicle trafficking. Its expression is…”
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Cancer stem cells: a new framework for the design of tumor therapies by Garvalov, Boyan K., Acker, Till

“…Modern tumor therapy has achieved considerable progress, but many tumors remain refractory to treatment or relapse following initial remission. Recent evidence…”
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The crosstalk between glomerular endothelial cells and podocytes controls their responses to metabolic stimuli in diabetic nephropathy by Albrecht, Michael, Sticht, Carsten, Wagner, Tabea, Hettler, Steffen A., De La Torre, Carolina, Qiu, Jiedong, Gretz, Norbert, Albrecht, Thomas, Yard, Benito, Sleeman, Jonathan P., Garvalov, Boyan K.

“…In diabetic nephropathy (DN), glomerular endothelial cells (GECs) and podocytes undergo pathological alterations, which are influenced by metabolic changes…”
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IER2-induced senescence drives melanoma invasion through osteopontin by Kyjacova, Lenka, Saup, Rafael, Rönsch, Kerstin, Wallbaum, Sabine, Dukowic-Schulze, Stefanie, Foss, Amelia, Scherer, Sandra D., Rothley, Melanie, Neeb, Antje, Grau, Nicole, Thiele, Wilko, Thaler, Sonja, Cremers, Natascha, Sticht, Carsten, Gretz, Norbert, Garvalov, Boyan K., Utikal, Jochen, Sleeman, Jonathan P.

“…Expression of the immediate-early response gene IER2 has been associated with the progression of several types of cancer, but its functional role is poorly…”
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Rac1 regulates neuronal polarization through the WAVE complex by Tahirovic, Sabina, Hellal, Farida, Neukirchen, Dorothee, Hindges, Robert, Garvalov, Boyan K, Flynn, Kevin C, Stradal, Theresia E, Chrostek-Grashoff, Anna, Brakebusch, Cord, Bradke, Frank

“…Neuronal migration and axon growth, key events during neuronal development, require distinct changes in the cytoskeleton. Although many molecular regulators of…”
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Implications of Oxygen Homeostasis for Tumor Biology and Treatment by Garvalov, Boyan K, Acker, Till

“…Tumors serve as a prototype system to study the role of the hypoxic microenvironment and gain insight in the regulation oxygen homeostasis. A series of…”
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Cdc42 Regulates Cofilin during the Establishment of Neuronal Polarity by Garvalov, Boyan K, Flynn, Kevin C, Neukirchen, Dorothee, Meyn, Liane, Teusch, Nicole, Wu, Xunwei, Brakebusch, Cord, Bamburg, James R, Bradke, Frank

“…The establishment of polarity is an essential process in early neuronal development. Although a number of molecules controlling neuronal polarity have been…”
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Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells by Wu, Ruo-Lin, Sedlmeier, Georg, Kyjacova, Lenka, Schmaus, Anja, Philipp, Julia, Thiele, Wilko, Garvalov, Boyan K., Sleeman, Jonathan P.

“…BMP4/7-dependent expression of inhibitor of differentiation/DNA binding (Id) proteins 1 and 3 has been implicated in tumor progression and poor prognosis of…”
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Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia by Dietrich, Sascha, Hüllein, Jennifer, Hundemer, Michael, Lehners, Nicola, Jethwa, Alexander, Capper, David, Acker, Till, Garvalov, Boyan K, Andrulis, Mindaugas, Blume, Carolin, Schulte, Christoph, Mandel, Thomas, Meissner, Julia, Fröhling, Stefan, von Kalle, Christof, Glimm, Hanno, Ho, Anthony D, Zenz, Thorsten

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Increased Circulating Osteopontin Levels Promote Primary Tumour Growth, but Do Not Induce Metastasis in Melanoma by Saup, Rafael, Nair, Nidhi, Shen, Jingyi, Schmaus, Anja, Thiele, Wilko, Garvalov, Boyan K, Sleeman, Jonathan P

“…Osteopontin (OPN) is a phosphoprotein with diverse functions in various physiological and pathological processes. OPN expression is increased in multiple…”
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Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model by Haslinger, Denise, Waltes, Regina, Yousaf, Afsheen, Lindlar, Silvia, Schneider, Ines, Lim, Chai K, Tsai, Meng-Miao, Garvalov, Boyan K, Acker-Palmer, Amparo, Krezdorn, Nicolas, Rotter, Björn, Acker, Till, Guillemin, Gilles J, Fulda, Simone, Freitag, Christine M, Chiocchetti, Andreas G

“…Altered neuronal development is discussed as the underlying pathogenic mechanism of autism spectrum disorders (ASD). Copy number variations of 16p11.2 have…”
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The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment by Filatova, Alina, Acker, Till, Garvalov, Boyan K.

“…The initiation and progression of various types of tumors, including glioma, are driven by a population of cells with stem cell properties. Glioma stem cells…”
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Tes, a Specific Mena Interacting Partner, Breaks the Rules for EVH1 Binding by Boëda, Batiste, Briggs, David C., Higgins, Theresa, Garvalov, Boyan K., Fadden, Andrew J., McDonald, Neil Q., Way, Michael

“…The intracellular targeting of Ena/VASP family members is achieved via the interaction of their EVH1 domain with FPPPP sequence motifs found in a variety of…”
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Luminal particles within cellular microtubules by Garvalov, Boyan K, Zuber, Benoît, Bouchet-Marquis, Cédric, Kudryashev, Mikhail, Gruska, Manuela, Beck, Martin, Leis, Andrew, Frischknecht, Friedrich, Bradke, Frank, Baumeister, Wolfgang, Dubochet, Jacques, Cyrklaff, Marek

“…The regulation of microtubule dynamics is attributed to microtubule-associated proteins that bind to the microtubule outer surface, but little is known about…”
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Lamin B1 in cancer and aging by Garvalov, Boyan K, Muhammad, Sajjad, Dobreva, Gergana

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The role of hypoxic signalling in metastasis: towards translating knowledge of basic biology into novel anti-tumour strategies by Araos, Joaquín, Sleeman, Jonathan P., Garvalov, Boyan K.

“…Hypoxia is a characteristic feature of many cancer types, which ensues when the growth of a tumour outpaces its oxygen supply. The cellular response to reduced…”
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Isolation and culture of primary glioblastoma cells from human tumor specimens by Seidel, Sascha, Garvalov, Boyan K, Acker, Till

“…Cultured tumor cells are a central tool in cancer research and have provided fundamental insights in tumor biology. Recent evidence, however, indicates that…”
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