Search Results - "Garson, J A"

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate by MCCORMICK, A. L, BROWN, R. H, CUDKOWICZ, M. E, AL-CHALABI, A, GARSON, J. A

“…Retroviral involvement in amyotrophic lateral sclerosis (ALS) has been suspected for several years since the recognition that both murine and human…”
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Real-time PCR quantitation of hepatitis B virus DNA using automated sample preparation and murine cytomegalovirus internal control by Garson, J.A., Grant, P.R., Ayliffe, U., Ferns, R.B., Tedder, R.S.

“…Quantitation of circulating hepatitis B virus (HBV) DNA is important for monitoring disease progression and for assessing the response to antiviral therapy…”
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Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives by STEELE, A. J, AL-CHALABI, A, FERRANTE, K, CUDKOWICZ, M. E, BROWN, R. H, GARSON, J. A

“…Retroviral involvement in the etiology of sporadic ALS has been suspected for several years since the recognition that both murine and human retroviruses can…”
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Molecular Identification of a Novel Retrovirus Repeatedly Isolated from Patients with Multiple Sclerosis by Perron, H., Garson, J. A., Bedin, F., Beseme, F., Paranhos-Baccala, G., Komurian-Pradel, F., Mallet, F., Tuke, P. W., Voisset, C., Blond, J. L., Lalande, B., Seigneurin, J. M., Mandrand, B., The Collaborative Research Group on Multiple Sclerosis

“…The partial molecular characterization of multiple sclerosis (MS)-associated retrovirus (MSRV), a novel retrovirus previously called LM7, is reported. MSRV has…”
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Development and evaluation of a real-time RT-PCR assay for quantification of cell-free human immunodeficiency virus type 2 using a Brome Mosaic Virus internal control by Ferns, R.B., Garson, J.A.

“…Quantification of cell–free virus in plasma is important for monitoring disease progression and for assessing the response to antiretroviral therapy in both…”
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Quantitation of hepatitis delta virus using a single-step internally controlled real-time RT-qPCR and a full-length genomic RNA calibration standard by Ferns, R.B., Nastouli, E., Garson, J.A.

“…► A real-time RT-qPCR for quantitation of hepatitis D virus (HDV) has been developed. ► The novel calibration standard is full-length genomic HDV RNA…”
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Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis by Garson, JA, Tuke, PW, Giraud, P, Paranhos-Baccala, G, Perron, H

“…A study revealed that partial molecular characterization of multiple sclerosis associated retrovirus (MSRV) is distantly related to the endogenous retroviral…”
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Detection of hepatitis C viral sequences in blood donations by "nested" polymerase chain reaction and prediction of infectivity by Garson, J A, Tedder, R S, Briggs, M, Tuke, P, Glazebrook, J A, Trute, A, Parker, D, Barbara, J A, Contreras, M, Aloysius, S

“…Of 1100 blood donations tested during a prospective study of post-transfusion non-A, non-B hepatitis (NANBH), 6 (0.55%) were repeatedly reactive in a…”
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Detection of reverse transcriptase activity in the serum of patients with motor neurone disease by Andrews, W.D., Tuke, P.W., Al-Chalabi, A., Gaudin, P., Ijaz, S., Parton, M.J., Garson, J.A.

“…The recognition that both human and murine retroviruses can cause motor neurone disease‐like syndromes has raised the possibility that a retrovirus may be…”
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Enhanced detection by PCR of hepatitis C virus RNA by Garson, J A, Ring, C, Tuke, P, Tedder, R S

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Combination therapy with interferon alpha and ribavirin for chronic hepatitis C virus infection in thalassaemic patients by Telfer, P. T., Garson, J. A., Whitby, K., Grant, P. R., Yardumian, A., Hoffbrand, A. V., Wonke, B.

“…Hepatitis C virus (HCV) infection is common in multi‐transfused thalassaemic patients, and, in combination with transfusional iron overload, can result in…”
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Suramin blocks hepatitis C binding to human hepatoma cells in vitro by Garson, J.A., Lubach, D., Passas, J., Whitby, K., Grant, P.R.

“…It was demonstrated recently that the binding of dengue virus to its target cell receptor could be effectively blocked by both heparin and by the…”
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Detection of bacterial contamination in platelet concentrates from Brazilian donors by molecular amplification of the ribosomal 16S gene by Viana, J. D., Ferreira, S. C., Matana, S. R., Rossi, F., Patel, P., Garson, J. A., Rocha, V., Tedder, R., Mendrone‐Júnior, A., Levi, J. E.

“…Summary Objective The aim of our work was to establish a semi‐automated high‐throughput DNA amplification method for the universal screening of bacteria in…”
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Combination therapy with interferon-α plus N-acetyl cysteine for chronic hepatitis C: A placebo controlled double-blind multicentre study by Grant, P.R., Black, A., Garcia, N., Prieto, J., Garson, J.A.

“…A small pilot study in patients with chronic hepatitis C (HCV) infection suggested that antiviral treatment with interferon (IFN) plus N‐acetyl cysteine (NAC)…”
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Demonstration of viraemia patterns in haemophiliacs treated with hepatitis-C-virus-contaminated factor VIII concentrates by Garson, J A, Tuke, P W, Makris, M, Briggs, M, Machin, S J, Preston, F E, Tedder, R S

“…Sequential serum samples from previously untreated haemophiliacs in whom non-A, non-B hepatitis (NANBH) developed after they received factor VIII concentrate…”
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Infrequency of detection of particle‐associated MSRV/HERV‐W RNA in the synovial fluid of patients with rheumatoid arthritis by Gaudin, P., Ijaz, S., Tuke, P. W., Marcel, F., Paraz, A., Seigneurin, J. M., Mandrand, B., Perron, H., Garson, J. A.

“…Objectives. To determine whether the recently identified multiple sclerosis‐associated retrovirus, MSRV, is detectable in the serum and synovial fluid of…”
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Hepatitis C virus: evidence for sexual transmission by Tedder, R S, Gilson, R J, Briggs, M, Loveday, C, Cameron, C H, Garson, J A, Kelly, G E, Weller, I V

“…OBJECTIVE--To determined the prevalence of hepatitis C virus infection and associated risk factors in patients attending a genitourinary medicine clinic, as…”
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Analysis of clinical and virological factors associated with response to alpha interferon therapy in chronic hepatitis C by Garson, J A, Brillanti, S, Whitby, K, Foli, M, Deaville, R, Masci, C, Miglioli, M, Barbara, L

“…Interferon alpha (IFN-alpha) therapy is currently the treatment of choice for chronic hepatitis C (HCV) infection, but it fails to achieve a sustained response…”
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Development of a pan-retrovirus detection system for multiple sclerosis studies by Tuke, P. W., Perron, H., Bedin, F., Beseme, F., Garson, J. A.

“…Introduction ‐ Although recent claims implicating HTLV‐1 in multiple sclerosis (MS) have been refuted, several reports suggest that another, hitherto…”
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Development and evaluation of an internally controlled semiautomated PCR assay for quantification of cell-free cytomegalovirus by Tedder, R.S., Ayliffe, U., Preiser, W., Brink, N.S., Grant, P.R., Peggs, K.S., Mackinnon, S., Kreig-Schneider, F., Kirk, S., Garson, J.A.

“…Quantification of circulating human cytomegalovirus (HCMV) is useful in clinical contexts such as virological surveillance of bone marrow transplant recipients…”
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