Search Results - "Garside, Victoria C."
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Cell diversity and plasticity during atrioventricular heart valve EMTs
Published in Nature communications (09-09-2023)“…Epithelial-to-mesenchymal transitions (EMTs) of both endocardium and epicardium guide atrioventricular heart valve formation, but the cellular complexity and…”
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Notch Initiates the Endothelial-to-Mesenchymal Transition in the Atrioventricular Canal through Autocrine Activation of Soluble Guanylyl Cyclase
Published in Developmental cell (16-08-2011)“…The heart is the most common site of congenital defects, and valvuloseptal defects are the most common of the cardiac anomalies seen in the newborn. The…”
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3
Breaking constraint of mammalian axial formulae
Published in Nature communications (11-01-2022)“…The vertebral column of individual mammalian species often exhibits remarkable robustness in the number and identity of vertebral elements that form (known as…”
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4
Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation
Published in Cell reports (Cambridge) (09-10-2014)“…Cell fate acquisition is heavily influenced by direct interactions between master regulators and tissue-specific enhancers. However, it remains unclear how…”
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SOX9 modulates the expression of key transcription factors required for heart valve development
Published in Development (Cambridge) (15-12-2015)“…Heart valve formation initiates when endothelial cells of the heart transform into mesenchyme and populate the cardiac cushions. The transcription factor SOX9…”
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A Hox Code Defines Spinocerebellar Neuron Subtype Regionalization
Published in Cell reports (Cambridge) (19-11-2019)“…Coordinated movement requires the integration of many sensory inputs including proprioception, the sense of relative body position and force associated with…”
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MIST1 regulates the pancreatic acinar cell expression of Atp2c2, the gene encoding secretory pathway calcium ATPase 2
Published in Experimental cell research (15-10-2010)“…MIST1 is a transcription factor expressed in pancreatic acinar cells and other serous exocrine cells. Mice harboring a targeted deletion of the Mist1 gene (…”
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Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development
Published in Cellular and molecular life sciences : CMLS (01-08-2013)“…Congenital heart defects affect approximately 1–5 % of human newborns each year, and of these cardiac defects 20–30 % are due to heart valve abnormalities…”
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Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α
Published in npj metabolic health and disease (06-11-2024)“…Protein phosphatase 2A (PP2A) regulatory subunit B55α has been implicated in the transcriptional regulation of cardiac growth and fibrosis by suppressing…”
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10
A Notch‐dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion
Published in Developmental dynamics (01-07-2014)“…Background: Valvuloseptal defects are the most common congenital heart defects. Notch signaling–induced endothelial‐to‐mesenchymal transition (EMT) in the…”
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11
Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development
Published in Developmental biology (15-01-2015)“…Huntington disease (HD) is an adult-onset neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms that is caused by a CAG…”
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Identification of a Transcription Factor, BHLHB8, Involved in Mouse Seminal Vesicle Epithelium Differentiation and Function
Published in Biology of reproduction (2008)“…The seminal vesicle is a male accessory sex organ that develops from segments of the Wolffian duct adjacent to the urogenital sinus. It produces most of the…”
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Identification of a Transcription Factor, BHLHB8, Involved in Mouse Seminal Vesicle Epithelium Differentiation and Function1
Published in Biology of reproduction (01-01-2008)“…The seminal vesicle is a male accessory sex organ that develops from segments of the Wolffian duct adjacent to the urogenital sinus. It produces most of the…”
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14
Co-ordinating Notch, BMP, and TGF-[beta] signaling during heart valve development
Published in Cellular and molecular life sciences : CMLS (01-08-2013)“…Congenital heart defects affect approximately 1-5 % of human newborns each year, and of these cardiac defects 20-30 % are due to heart valve abnormalities…”
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15
Revealing the Hox code in developing spinocerebellar neurons
Published in Mechanisms of development (01-07-2017)Get full text
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