Search Results - "Garry, Robert F"
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After the pandemic: perspectives on the future trajectory of COVID-19
Published in Nature (London) (26-08-2021)“…There is a realistic expectation that the global effort in vaccination will bring the pandemic caused by severe acute respiratory syndrome coronavirus 2…”
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The origins of SARS-CoV-2: A critical review
Published in Cell (16-09-2021)“…Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest…”
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Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 in Aerosol Suspensions
Published in Emerging infectious diseases (01-09-2020)“…We aerosolized severe acute respiratory syndrome coronavirus 2 and determined that its dynamic aerosol efficiency surpassed those of severe acute respiratory…”
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Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Published in Science (American Association for the Advancement of Science) (12-09-2014)“…In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78…”
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Structural basis for antibody-mediated neutralization of Lassa virus
Published in Science (American Association for the Advancement of Science) (02-06-2017)“…The arenavirus Lassa causes severe hemorrhagic fever and a significant disease burden in West Africa every year. The glycoprotein, GPC, is the sole antigen…”
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Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Published in Nature communications (17-08-2020)“…Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD) and Lassa fever (LF), highlight the urgent need for sensitive,…”
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Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018
Published in The New England journal of medicine (01-11-2018)“…An increase in Lassa fever cases was identified in Nigeria this year. In this analysis of the infecting viruses, the predominant mode of transmission appeared…”
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Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever
Published in Nature medicine (01-10-2017)“…Thomas Geisbert and colleagues show that a cocktail of monoclonal antibodies protects cynomolgus monkeys from lethal Lassa fever virus infection, including…”
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Predicting the evolution of the Lassa virus endemic area and population at risk over the next decades
Published in Nature communications (27-09-2022)“…Lassa fever is a severe viral hemorrhagic fever caused by a zoonotic virus that repeatedly spills over to humans from its rodent reservoirs. It is currently…”
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Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes
Published in Virology journal (26-07-2021)Get full text
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Lassa fever — the road ahead
Published in Nature reviews. Microbiology (01-02-2023)“…Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other countries in West Africa. Spillover to humans occurs frequently and…”
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Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV
Published in Nature structural & molecular biology (01-06-2016)“…The crystal structure of the GP1–GP2 complex of the prototypical arenavirus LCMV in prefusion form sheds light on the conformational changes that the…”
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A Unified Framework for the Infection Dynamics of Zoonotic Spillover and Spread
Published in PLoS neglected tropical diseases (02-09-2016)“…A considerable amount of disease is transmitted from animals to humans and many of these zoonoses are neglected tropical diseases. As outbreaks of SARS, avian…”
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Proteomics Computational Analyses Suggest that the Antennavirus Glycoprotein Complex Includes a Class I Viral Fusion Protein (α-Penetrene) with an Internal Zinc-Binding Domain and a Stable Signal Peptide
Published in Viruses (14-08-2019)“…A metatranscriptomic study of RNA viruses in cold-blooded vertebrates identified two related viruses from frogfish ( ) that represent a new genus in the family…”
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Proteomics Computational Analyses Suggest That the Envelope Glycoproteins of Segmented Jingmen Flavi-Like Viruses are Class II Viral Fusion Proteins (b-Penetrenes) with Mucin-Like Domains
Published in Viruses (27-02-2020)“…Jingmen viruses are newly described segmented flavi-like viruses that have a worldwide distribution in ticks and have been associated with febrile illnesses in…”
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Endotheliopathy and Platelet Dysfunction as Hallmarks of Fatal Lassa Fever
Published in Emerging infectious diseases (01-11-2020)“…Lassa fever (LF) causes multisystem disease and has a fatality rate <70%. Severe cases exhibit abnormal coagulation, endothelial barrier disruption, and…”
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Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model
Published in Viruses (01-08-2022)“…For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like…”
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The evidence remains clear: SARS-CoV-2 emerged via the wildlife trade
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2022)Get full text
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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: the case of lassa fever
Published in PLoS neglected tropical diseases (01-01-2015)“…Zoonotic infections, which transmit from animals to humans, form the majority of new human pathogens. Following zoonotic transmission, the pathogen may already…”
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