Search Results - "Garruto, R M"

Impact of white‐tailed deer on the spread of Borrelia burgdorferi by ROOME, A., HILL, L., AL‐FEGHALI, V., MURNOCK, C. G., GOODSELL, J. A., SPATHIS, R., GARRUTO, R. M.

“…There is a public perception that the white‐tailed deer Odocoileus virginianus (Artiodactyla: Cervidae) is the main reservoir supporting the maintenance and…”
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Aluminium in Alzheimer's disease: are we still at a crossroad? by Gupta, Veer Bala, Anitha, S, Hegde, M L, Zecca, L, Garruto, R M, Ravid, R, Shankar, S K, Stein, R, Shanmugavelu, P, Jagannatha Rao, K S

“…Aluminium, an environmentally abundant non-redox trivalent cation has long been implicated in the pathogenesis of Alzheimer's disease (AD). However, the…”
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Tau is a candidate gene for chromosome 17 frontotemporal dementia by Poorkaj, P, Bird, T D, Wijsman, E, Nemens, E, Garruto, R M, Anderson, L, Andreadis, A, Wiederholt, W C, Raskind, M, Schellenberg, G D

“…Frontotemporal dementia with parkinsonism, chromosome 17 type (FTDP-17), a recently defined disease entity, is clinically characterized by personality changes…”
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ALS and PDC of Guam: Forty-year follow-up by PLATO, C. C, GALASKO, D, GARRUTO, R. M, PLATO, M, GAMST, A, CRAIG, U.-K, TORRES, J. M, WIEDERHOLT, W

“…It was noticed in the mid-1950s that the incidence of ALS and parkinsonism--dementia complex (PDC) were much higher on Guam than anywhere else in the world. In…”
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Quantitative and qualitative analysis of stability for 16 serum immunoregulators over 50 freeze–thaw cycles by Chowdhury, R. N., Armato, A., Culver, E., Shteynman, L., Kurien, C., Cradin, B., Margolin, F., Nguyen, T., Cardona, C., Kabir, N., Garruto, R. M., Lum, J. K., Wander, K.

“…Objectives To evaluate the reliability of data from the assay of bio‐archived specimens, a 50‐freeze–thaw‐cycle (FTC) degradation study of fresh sera was…”
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Role of DNA dynamics in Alzheimer's disease by Vasudevaraju, P, Bharathi, Garruto, R.M, Sambamurti, K, Rao, K.S.J

“…Abstract DNA is a dynamic molecule, the conformation of which plays a major role in biological function. The non-B-form of DNA conformations are reported in…”
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Morphological growth and thorax dimensions among Tibetan compared to Han children, adolescents and young adults born and raised at high altitude by Weitz, C. A., Garruto, R. M., Chin, Chen-Ting, Liu, Ji-Chuan

“…Background: Studies comparing the growth of indigenous high-altitude Aymara children and children of low-altitude European descent who have been born and…”
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Natural Experimental Models: The Global Search for Biomedical Paradigms among Traditional, Modernizing, and Modern Populations by Garruto, R. M., Little, M. A., James, G. D., Brown, D. E.

“…During the past four decades, biomedical scientists have slowly begun to recognize the unique opportunities for studying biomedical processes, disease…”
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Pacific paradigms of environmentally-induced neurological disorders: clinical, epidemiological and molecular perspectives by Garruto, R M

“…During the past quarter century biomedical scientists have begun to recognize the unique opportunities for studying disease etiology and mechanisms of…”
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Six-year follow-up of a point-source exposure to CWD contaminated venison in an Upstate New York community: risk behaviours and health outcomes 2005–2011 by Olszowy, K.M, Lavelle, J, Rachfal, K, Hempstead, S, Drouin, K, Darcy, J.M, Reiber, C, Garruto, R.M

“…Abstract Objectives It is currently unknown whether chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, is transmissible to…”
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Highly Divergent Molecular Variants of Human T-Lymphotropic Virus Type I from Isolated Populations in Papua New Guinea and the Solomon Islands by GESSAIN, A, YANAGIHARA, R, FRANCHINI, G, GARRUTO, R. M, JENKINS, C. L, ADJUKIEWICZ, A. B, GALLO, R. C, CARLETON GAJDUSEK, D

“…To determine the molecular genetic relationship between Melanesian strains of human T-lymphotropic virus type I (HTLV-I) and cosmopolitan prototype HTLV-I, we…”
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Concentrations of zinc and iron in the brains of Guamanian patients with amyotrophic lateral sclerosis and parkinsonism-dementia by Yasui, M, Ota, K, Garruto, R M

“…Simultaneous measurements of zinc (Zn) and iron (Fe) concentrations were determined using neutron activation analysis in gray and white matter of the frontal…”
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Low-calcium, high-aluminum diet-induced motor neuron pathology in cynomolgus monkeys by GARRUTO, R. M, SHANKAR, S. K, YANAGIHARA, R, SALAZAR, A. M, AMYX, H. L, GAJDUSEK, D. C

“…Long-term epidemiological studies indicate that environmental factors play a causative role in high-incidence amyotrophic lateral sclerosis (ALS) and…”
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Imaging of Calcium and Aluminum in Neurofibrillary Tangle-Bearing Neurons in Parkinsonism-Dementia of Guam by Garruto, Ralph M., Fukatsu, Ryo, Yanagihara, Richard, Gajdusek, D. Carleton, Hook, Gregory, Fiori, Charles E.

“…We report the distribution and imaging of calcium and aluminum in neurofibrillary tangle (NFT)-bearing neurons within Sommer's sector of the hippocampus in…”
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Aluminum, tau protein, and Alzheimer's disease: an important link? by Savory, J, Garruto, R M

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Growth of Qinghai Tibetans living at three different high altitudes by Weitz, Charles A., Garruto, Ralph M., Chin, Chen-Ting, Liu, Ji-Chuan, Liu, Rui-Ling, He, Xing

“…This study compares the stature, weight, skinfolds, upper arm muscle area, and chest dimensions of Tibetan children, adolescents, and young adults who were…”
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Amyloid of Neurofibrillary Tangles of Guamanian Parkinsonism-Dementia and Alzheimer Disease Share Identical Amino Acid Sequence by Guiroy, Don C., Miyazaki, Masayuki, Multhaup, Gerd, Fischer, Peter, Garruto, Ralph M., Beyreuther, Konrad, Masters, Colin L., Simms, Gail, Gibbs, Clarence J., Gajdusek, D. Carleton

“…The presence of abundant intraneuronal amyloid in the form of neurofibrillary tangles (NFT) in the brains of Guamanian parkinsonism-dementia patients and the…”
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Comparative study of chronic aluminum-induced neurofilamentous aggregates with intracytoplasmic inclusions of amyotrophic lateral sclerosis by WAKAYAMA, I, NERURKAR, V. R, STRONG, M. J, GARRUTO, R. M

“…Amyotrophic lateral sclerosis (ALS) is characterized neuropathologically by chromatolysis, Bunina bodies, hyaline inclusions, skein-like inclusions and axonal…”
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Aluminum-induced chronic myelopathy in rabbits by Strong, M J, Wolff, A V, Wakayama, I, Garruto, R M

“…Young adult New Zealand white rabbits, inoculated intracisternally once monthly with 100 micrograms AlCl3, developed progressive hyperreflexia, hypertonia,…”
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Effects of calcium-deficient diets on manganese deposition in the central nervous system and bones of rats by Yasui, M, Ota, K, Garruto, R M

“…The presence of both aluminum (Al) and manganese (Mn) in central nervous system tissues (CNS) has been reported in Parkinson's disease and in…”
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