Search Results - "Garro, Hugo A"

DNA Related Enzymes as Molecular Targets for Antiviral and Antitumoral Chemotherapy. A Natural Overview of the Current Perspectives by Garro, Hugo A, Pungitore, Carlos R

“…The discovery of new chemotherapeutic agents still remains a continuous goal to achieve. DNA polymerases and topoisomerases act in nucleic acids metabolism…”
Get more information

High-degree right bundle branch block obscuring the diagnosis of Brugada electrocardiographic pattern by Chiale, Pablo A., MD, Garro, Hugo A., MD, Fernández, Pablo A., MD, Elizari, Marcelo V., MD

Get full text

Coumarins as Potential Inhibitors of DNA Polymerases and Reverse Transcriptases. Searching New Antiretroviral and Antitumoral Drugs by Garro, Hugo A, Pungitore, Carlos R

“…Human Immunodeficiency Virus (HIV) is the viral agent of Acquired Immunodeficiency Syndrome (AIDS), and at present, there is no effective vaccine against HIV…”
Get more information

Clinical Evaluation of Losartan and Diltiazem on the Development of T-Wave Memory by Right Apical Ventricular Pacing by Chiale, Pablo A., MD, Etcheverry, Daniel, MD, Pastori, Julio D., MD, Garro, Hugo A., MD, Fernández, Pablo A., MD, González, Mario D., MD, Elizari, Marcelo V., MD

“…Before and after diltiazem or losartan administration, the T-wave axis on the frontal plane, the T-wave amplitude (in lead III and in a precordial lead with…”
Get full text

The Multiple Electrocardiographic Manifestations of Ventricular Repolarization Memory by Chiale, Pablo A, Etcheverry, Daniel, Pastori, Julio D, Fernandez, Pablo A, Garro, Hugo A, González, Mario D, Elizari, Marcelo V

“…T wave "memory" is a peculiar variety of cardiac remodeling caused by a transient change in the course of ventricular depolarization (due to ventricular…”
Get full text

Diuretic activity of Euphorbia serpens extracts in Wistar rats by Garro, María F., Gil, Raúl A., Leporati, Jorge, Garro, Hugo A.

“…Euphorbia serpens has been used in central-west region of Argentina in traditional medicine as diuretic plant. The aim of this present study was to evaluate…”
Get full text

Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations by Buratti, Fiamma A., Boeffinger, Nicola, Garro, Hugo A., Flores, Jesica S., Hita, Francisco J., Gonçalves, Phelippe do Carmo, Copello, Federico dos Reis, Lizarraga, Leonardo, Rossetti, Giulia, Carloni, Paolo, Zweckstetter, Markus, Outeiro, Tiago F., Eimer, Stefan, Griesinger, Christian, Fernández, Claudio O.

“…Recent studies revealed that molecular events related with the physiology and pathology of αS might be regulated by specific sequence motifs in the primary…”
Get full text

Verbascoside, synthetic derivatives and other glycosides from Argentinian native plant species as potential antitumoral agents by Garro, Hugo A., Bruna-Haupt, Ezequiel, Cianchino, Valeria, Malizia, Florencia, Favier, Silvina, Menacho-Márquez, Mauricio, Cifuente, Diego, Fernández, Claudio O., Pungitore, Carlos R.

“…A phytochemical study was performed on three native plant species from the central-western zone of Argentina: Buddleja cordobensis Grisebach, Baccharis…”
Get full text

Gold‐Catalyzed Cycloisomerizations of Functionalyzed Cyclopropyl Alkynes: the Cases of Carboxamides and Alcohols by Fernández‐García, Jesús M., Garro, Hugo A., Fernández‐García, Laura, García‐García, Patricia, Fernández‐Rodríguez, Manuel A., Merino, Isabel, Aguilar, Enrique

“…Push‐pull alkynylcyclopropane derivatives are claimed as suitable and active substrates for gold‐catalyzed transformations. Thus, 2(3H)‐azepinones can be…”
Get full text

Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: a structural and cell-based study by González, Nazareno, Gentile, Iñaki, Garro, Hugo A., Delgado-Ocaña, Susana, Ramunno, Carla F., Buratti, Fiamma A., Griesinger, Christian, Fernández, Claudio O.

“…The discovery of aggregation inhibitors and the elucidation of their mechanism of action are key in the quest to mitigate the toxic consequences of amyloid…”
Get full text

Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: binding ligands, affinity and structural features by Gentile, Iñaki, Garro, Hugo A, Susana Delgado Ocaña, Gonzalez, Nazareno, Strohäker, Timo, Schibich, Daniela, Quintanar, Liliana, Sambrotta, Luis, Zweckstetter, Markus, Griesinger, Christian, Márquez, Mauricio Menacho, Fernández, Claudio O

“…The identity of the Cu(i) binding ligands at Met-X3-Met site of AcαS and its role into the affinity and structural properties of the interaction were…”
Get full text

Intraventricular aberrancy, pseudo-supernormality and intrahisian conduction “gap” in premature junctional beats by Siles, Natalia, Baranchuk, Adrián, Garro, Hugo A, Chiale, Pablo A

Get full text

A new iridoid, verbascoside and derivatives with inhibitory activity against Taq DNA polymerase by Garro, Hugo A., García, Celina, Martín, Victor S., Tonn, Carlos E., Pungitore, Carlos R.

“…[Display omitted] DNA polymerases are enzymes that play a crucial role in DNA metabolism such as replication, repair, transcription, recombination, and…”
Get full text

Collection of alkenylcoumarin derivatives as Taq DNA polymerase inhibitors: SAR and in silico simulations by Bruna-Haupt, Ezequiel, Garro, Hugo A., Gutiérrez, Lucas, Pungitore, Carlos R.

“…Using a feasible method, we generated a small focused library of structurally related alkenylcoumarins. These compounds were evaluated as potential antitumoral…”
Get full text

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents by Bruna-Haupt, Ezequiel F., Perretti, Marcelle D., Garro, Hugo A., Carrillo, Romen, Machín, Félix, Lorenzo-Castrillejo, Isabel, Gutiérrez, Lucas, Vega-Hissi, Esteban G., Mamberto, Macarena, Menacho-Marquez, Mauricio, Fernández, Claudio O., García, Celina, Pungitore, Carlos R.

“…A library of structurally related coumarins was generated through synthesis reactions and chemical modification reactions to obtain derivatives with…”
Get full text

Interaction of Cu(i) with the Met-X 3 -Met motif of alpha-synuclein: binding ligands, affinity and structural features by Gentile, Iñaki, Garro, Hugo A, Delgado Ocaña, Susana, Gonzalez, Nazareno, Strohäker, Timo, Schibich, Daniela, Quintanar, Liliana, Sambrotta, Luis, Zweckstetter, Markus, Griesinger, Christian, Menacho Márquez, Mauricio, Fernández, Claudio O

“…The identity of the Cu(i) binding ligands at Met-X3-Met site of AcαS and its role into the affinity and structural properties of the interaction were…”
Get full text

Inhibition of reverse transcriptase and Taq DNA polymerase by compounds possessing the coumarin framework by Garro Hugo, A., Manzur Jimena, M., Ciuffo Gladys, M., Tonn Carlos, E., Pungitore Carlos, R.

“…Coumarin derivatives were prepared using natural products isolated from plants belonging in the Pterocaulon genus (Asteraceae) and commercial drugs. Some…”
Get full text

Inappropriate sinus tachycardia may be related to an immunologic disorder involving cardiac beta andrenergic receptors by Chiale, Pablo A, Garro, Hugo A, Schmidberg, Jorge, Sánchez, Rubén A, Acunzo, Rafael S, Lago, Manuel, Levy, Gabriela, Levin, Mariano

“…The mechanisms underlying inappropriate sinus tachycardia are not fully known. An autonomic imbalance seems to play a role, but no attempts have been made to…”
Get more information

A shifting heart shifts the transition index by Caldwell, Jane, Atienza, Augusto, Garro, Hugo A

Get full text

The mechanisms of spontaneous termination of reentrant supraventricular tachycardias by Chiale, Pablo A, Baranchuk, Adrián, González, Mario D, Sánchez, Rubén A, Garro, Hugo A, Fernández, Pablo A, Avalos, Carlos Quiroga, Enriquez, Andres, Elizari, Marcelo V

“…Abstract Background Atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT) often terminate spontaneously,…”
Get full text