Search Results - "Garrigue, Philippe"
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Uremic Toxic Blood-Brain Barrier Disruption Mediated by AhR Activation Leads to Cognitive Impairment during Experimental Renal Dysfunction
Published in Journal of the American Society of Nephrology (01-07-2020)“…Uremic toxicity may play a role in the elevated risk of developing cognitive impairment found among patients with CKD. Some uremic toxins, like indoxyl…”
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Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors
Published in Proceedings of the National Academy of Sciences - PNAS (06-11-2018)“…Bioimaging plays an important role in cancer diagnosis and treatment. However, imaging sensitivity and specificity still constitute key challenges…”
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3
A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging
Published in Chemical communications (Cambridge, England) (01-01-2020)“…Bioimaging has revolutionized modern medicine, and nanotechnology can offer further specific and sensitive imaging. We report here an amphiphilic dendrimer…”
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A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate Labeling?
Published in Molecules (Basel, Switzerland) (07-08-2019)“…Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron emission tomography (PET) imaging, for both preclinical and…”
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Thromboxane-prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats
Published in Critical care (London, England) (11-02-2019)“…Several lipid metabolites in cerebrospinal fluid are correlated with poor outcomes in aneurysmal subarachnoid haemorrhage. Most of these metabolites bind to…”
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Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease
Published in International journal of molecular sciences (03-04-2020)“…Cardiovascular complications observed in chronic kidney disease (CKD) are associated with aryl hydrocarbon receptor (AhR) activation by tryptophan-derived…”
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Medication reconciliation enhances the accuracy of gastric emptying scintigraphy
Published in EJNMMI radiopharmacy and chemistry (26-09-2024)“…Background Gastroparesis (GP) is a prevalent sensorimotor disorder characterized by delayed gastric emptying without mechanical obstruction, posing significant…”
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Long‐Term Recovery After Endothelial Colony‐Forming Cells or Human Umbilical Cord Blood Cells Administration in a Rat Model of Neonatal Hypoxic‐Ischemic Encephalopathy
Published in Stem cells translational medicine (01-11-2017)“…Neonatal hypoxic‐ischemic encephalopathy (NHIE) is a dramatic perinatal complication, associated with poor neurological prognosis despite neuroprotection by…”
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Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides
Published in EJNMMI research (02-03-2020)“…Background Targeting G protein-coupled receptors on the surface of cancer cells with peptide ligands is a promising concept for the selective tumor delivery of…”
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10
Sublingual Atropine Administration as a Tool to Decrease Salivary Glands' PSMA-Ligand Uptake: A Preclinical Proof of Concept Study Using [ 68 Ga]Ga-PSMA-11
Published in Pharmaceutics (16-06-2022)“…Prostate Specific Membrane Antigen (PSMA)-directed radionuclide therapy has gained an important role in the management of advanced castration-resistant…”
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Tracking Radiolabeled Endothelial Microvesicles Predicts Their Therapeutic Efficacy: A Proof-of-Concept Study in Peripheral Ischemia Mouse Model Using SPECT/CT Imaging
Published in Pharmaceutics (01-01-2022)“…Microvesicles, so-called endothelial large extracellular vesicles (LEVs), are of great interest as biological markers and cell-free biotherapies in…”
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Single photon emission computed tomography imaging of cerebral blood flow, blood–brain barrier disruption, and apoptosis time course after focal cerebral ischemia in rats
Published in International journal of stroke (01-01-2016)“…Background Cerebral ischemia is a leading cause of disability worldwide and no other effective therapy has been validated to date than intravenous…”
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Carbidopa Capsules for Insulinoma Diagnostic: Compounding and Stability Study
Published in Pharmaceutical technology in hospital pharmacy (25-02-2020)“…Abstract Background Carbidopa is a drug mainly used to treat Parkinson’s disease. Associations with levodopa or with levodopa/entacapone are commercialized,…”
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Have you looked for “stranger things” in your automated PET dose dispensing system? A process and operators qualification scheme
Published in EJNMMI radiopharmacy and chemistry (13-06-2019)“…Background Many nuclear medicine departments have equipped themselves with automated dispensing systems (ADS) for PET radiopharmaceuticals, in both the…”
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Comparison of a New 68Ga-Radiolabelled PET Imaging Agent sCD146 and RGD Peptide for In Vivo Evaluation of Angiogenesis in Mouse Model of Myocardial Infarction
Published in Cells (Basel, Switzerland) (03-09-2021)“…Ischemic vascular diseases are associated with elevated tissue expression of angiomotin (AMOT), a promising molecular target for PET imaging. On that basis, we…”
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Succinate Injection Rescues Vasculature and Improves Functional Recovery Following Acute Peripheral Ischemia in Rodents: A Multimodal Imaging Study
Published in Cells (Basel, Switzerland) (02-04-2021)“…Succinate influences angiogenesis and neovascularization via a hormonelike effect on G-protein-coupled receptor 91 (GPR91). This effect has been demonstrated…”
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Application and Dosimetric Requirements for Gallium-68–labeled Somatostatin Analogues in Targeted Radionuclide Therapy for Gastroenteropancreatic Neuroendocrine Tumors
Published in PET clinics (01-10-2015)“…Neuroendocrine tumors (NETs) are associated with variable prognosis, with grade 1 and 2 NETs having more favorable outcomes than grade 3. Patients with…”
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Long-term administration of resveratrol at low doses improves neurocognitive performance as well as cerebral blood flow and modulates the inflammatory pathways in the brain
Published in The Journal of nutritional biochemistry (01-11-2021)“…There is an increasing prevalence of coincident cerebrovascular deficiency and cognitive dysfunction with aging. Increased oxidative stress as well as…”
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Short-Term Biological Toxicity Prediction of [ 177 Lu]Lutetium-Oxodotreotide: An Original Retrospective Analysis
Published in Cancer biotherapy & radiopharmaceuticals (01-06-2024)“…[ Lu]Lutetium (Lu)-oxodotreotide is a radiopharmaceutical drug used as peptide receptor radionuclide therapy (PRRT) for somatostatin receptor-expressing…”
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Highlights of the 35th EANM Annual Congress 2022, onsite edition in Barcelona, Spain: “FROM BARCELONA WITH LOVE”
Published in European journal of nuclear medicine and molecular imaging (01-09-2023)“…Diets rich in plant-based foods are encouraged for human health and to preserve resources and the environment but the nutritional quality and safety of such…”
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