Search Results - "Garrido, Federico"

HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy by Anderson, Per, Aptsiauri, Natalia, Ruiz-Cabello, Francisco, Garrido, Federico

“…T cell-mediated immune therapies have emerged as a promising treatment modality in different malignancies including colorectal cancer (CRC). However, only a…”
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The urgent need to recover MHC class I in cancers for effective immunotherapy by Garrido, Federico, Aptsiauri, Natalia, Doorduijn, Elien M, Garcia Lora, Angel M, van Hall, Thorbald

“…Highlights • Tumor immune escape compromises the efficacy of cancer immunotherapy. • Loss of MHC class I expression is a frequent event in cancer cells. •…”
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“Hard” and “soft” lesions underlying the HLA class I alterations in cancer cells: Implications for immunotherapy by Garrido, Federico, Cabrera, Teresa, Aptsiauri, Natalia

“…The ability of cancer cells to escape from the natural or immunotherapy‐induced antitumor immune response is often associated with alterations in the tumor…”
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MHC heterogeneity and response of metastases to immunotherapy by Algarra, Ignacio, Garrido, Federico, Garcia-Lora, Angel M.

“…In recent years, immunotherapy has proven to be an effective treatment against cancer. Cytotoxic T lymphocytes perform an important role in this anti-tumor…”
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Metastases in immune-mediated dormancy: a new opportunity for targeting cancer by Romero, Irene, Garrido, Federico, Garcia-Lora, Angel M

“…The aim of any anticancer treatment is to avoid, control, or eliminate disseminated tumor cells. Clinical and experimental evidence has revealed that…”
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Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes by Bernal, Monica, Ruiz-Cabello, Francisco, Concha, Angel, Paschen, Annette, Garrido, Federico

“…Classical MHC molecules present processed peptides from endogenous protein antigens on the cell surface, which allows CD8 + cytotoxic T lymphocytes (CTLs) to…”
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Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors by RUSAKIEWICZ, Sylvie, SEMERARO, Michaela, CHAIGNEAU, Loic, LE BRUN-LY, Valérie, DUBREUIL, Patrice, CREMER, Isabelle, CAIGNARD, Anne, POIRIER-COLAME, Vichnou, CHABA, Kariman, FLAMENT, Caroline, HALAMA, Niels, JÄGER, Dirk, SARABI, Matthieu, EGGERMONT, Alexander, BONVALOT, Sylvie, COMMO, Frédéric, TERRIER, Philippe, OPOLON, Paule, EMILE, Jean-François, COINDRE, Jean-Michel, KROEMER, Guido, CHAPUT, Nathalie, LE CESNE, Axel, DESBOIS, Mélanie, BLAY, Jean-Yves, ZITVOGEL, Laurence, LOCHER, Clara, MENDEZ, Rosa, VIMOND, Nadège, CONCHA, Angel, GARRIDO, Federico, ISAMBERT, Nicolas

“…Cancer immunosurveillance relies on effector/memory tumor-infiltrating CD8(+) T cells with a T-helper cell 1 (TH1) profile. Evidence for a natural killer (NK)…”
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Scientific production in biodiversity: the gender gap continues in Brazilian universities by León, Federico Garrido-DE, Romero, Jair H Castro, Garey, Michel V, Eleuterio, Ana Alice

“…Scientometrics enables us to comprehend the interests and trends in scientific knowledge production and dissemination. In this study, we evaluate the effects…”
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Negative Clinical Evolution in COVID-19 Patients Is Frequently Accompanied With an Increased Proportion of Undifferentiated Th Cells and a Strong Underrepresentation of the Th1 Subset by Gutiérrez-Bautista, Juan Francisco, Rodriguez-Nicolas, Antonio, Rosales-Castillo, Antonio, Jiménez, Pilar, Garrido, Federico, Anderson, Per, Ruiz-Cabello, Francisco, López-Ruz, Miguel Ángel

“…The severity of SARS-CoV-2 infection has been related to uncontrolled inflammatory innate responses and impaired adaptive immune responses mostly due to…”
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‘No State, No Masters’: Café Lavandería in Tokyo, Music, and Anticapitalism in a Cultural Environment by González Dávila, María José, Pérez Garrido, Federico Fco

“…This paper is part of a series of research that these authors are conducting to study the linguistic landscape of the Tokyo megacity. In this instance, our…”
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Tumor Escape Phenotype in Bladder Cancer Is Associated with Loss of HLA Class I Expression, T-Cell Exclusion and Stromal Changes by Gil-Julio, Hernani, Perea, Francisco, Rodriguez-Nicolas, Antonio, Cozar, Jose Manuel, González-Ramirez, Amanda Rocío, Concha, Angel, Garrido, Federico, Aptsiauri, Natalia, Ruiz-Cabello, Francisco

“…Cancer eradication and clinical outcome of immunotherapy depend on tumor cell immunogenicity, including HLA class I (HLA-I) and PD-L1 expression on malignant…”
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MHC class I antigens, immune surveillance, and tumor immune escape by Garcia-Lora, Angel, Algarra, Ignacio, Garrido, Federico

“…Oncogenic transformation in human and experimental animals is not necessarily followed by the appearance of a tumor mass. The immune system of the host can…”
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Colorectal Cancer Classification and Cell Heterogeneity: A Systems Oncology Approach by Blanco-Calvo, Moisés, Concha, Ángel, Figueroa, Angélica, Garrido, Federico, Valladares-Ayerbes, Manuel

“…Colorectal cancer is a heterogeneous disease that manifests through diverse clinical scenarios. During many years, our knowledge about the variability of…”
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Study of HLA-A, -B, -C, -DRB1 and -DQB1 polymorphisms in COVID-19 patients by Gutiérrez-Bautista, Juan Francisco, Rodriguez-Nicolas, Antonio, Rosales-Castillo, Antonio, López-Ruz, Miguel Ángel, Martín-Casares, Antonia María, Fernández-Rubiales, Alonso, Anderson, Per, Garrido, Federico, Ruiz-Cabello, Francisco, López-Nevot, Miguel Ángel

“…Human leukocyte antigen (HLA) plays an important role in immune responses to infections, especially in the development of acquired immunity. Given the high…”
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The Escape of Cancer from T Cell-Mediated Immune Surveillance: HLA Class I Loss and Tumor Tissue Architecture by Garrido, Federico, Perea, Francisco, Bernal, Mónica, Sánchez-Palencia, Abel, Aptsiauri, Natalia, Ruiz-Cabello, Francisco

“…Tumor immune escape is associated with the loss of tumor HLA class I (HLA-I) expression commonly found in malignant cells. Accumulating evidence suggests that…”
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MHC Intratumoral Heterogeneity May Predict Cancer Progression and Response to Immunotherapy by Romero, Irene, Garrido, Cristina, Algarra, Ignacio, Chamorro, Virginia, Collado, Antonia, Garrido, Federico, Garcia-Lora, Angel M

“…An individual tumor can present intratumoral phenotypic heterogeneity, containing tumor cells with different phenotypes that do not present irreversible…”
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Genomic loss of HLA alleles may affect the clinical outcome in low-risk myelodysplastic syndrome patients by Montes, Paola, Kerick, Martin, Bernal, Mónica, Hernández, Francisca, Jiménez, Pilar, Garrido, Pilar, Márquez, Ana, Jurado, Manuel, Martin, Javier, Garrido, Federico, Ruiz-Cabello, Francisco

“…The Revised International Prognostic Score and some somatic mutations in myelodysplastic syndrome (MDS) are independently associated with transformation to…”
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Upregulation of HLA Class I Expression on Tumor Cells by the Anti-EGFR Antibody Nimotuzumab by Garrido, Greta, Rabasa, Ailem, Garrido, Cristina, Chao, Lisset, Garrido, Federico, García-Lora, Ángel M, Sánchez-Ramírez, Belinda

“…Defining how epidermal growth factor receptor (EGFR)-targeting therapies influence the immune response is essential to increase their clinical efficacy. A…”
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Fraying around the edges: negative effects of the invasive Tradescantia zebrina Hort. ex Bosse (Commelinaceae) on tree regeneration in the Atlantic Forest under different competitive and environmental conditions by Chiba de Castro, Wagner A, Xavier, Rafael O, Garrido, Federico H L, Romero, Jair H C, Peres, Cleto K, da Luz, Ruberval C

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A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation by Jiménez-Medina, Eva, Garcia-Lora, Angel, Paco, Laura, Algarra, Ignacio, Collado, Antonia, Garrido, Federico

“…Phytopharmacological studies of different Calendula extracts have shown anti-inflammatory, anti-viral and anti-genotoxic properties of therapeutic interest. In…”
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