Search Results - "Garrido, Alfonso"

Thorough characterization and stability of HP‐β‐cyclodextrin thymol inclusion complexes prepared by microwave technology: A required approach to a successful application in food industry by Rodríguez‐López, María Isabel, Mercader‐Ros, María Teresa, López‐Miranda, Santiago, Pellicer, José A, Pérez‐Garrido, Alfonso, Pérez‐Sánchez, Horacio, Núñez‐Delicado, Estrella, Gabaldón, José A

“…BACKGROUND The aims of the present study were to obtain a stable dry powder formulation of cyclodextrins (CDs) encapsulating thymol, for successful use as an…”
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Neural network and deep-learning algorithms used in QSAR studies: merits and drawbacks by Ghasemi, Fahimeh, Mehridehnavi, Alireza, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio

“…[Display omitted] •In this article, historical challenges of neural networks is reviewed in the QSAR studies.•An overview of the related deep learning works in…”
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Adherence to the "Mediterranean Diet" in Spain and Its Relationship with Cardiovascular Risk (DIMERICA Study) by Abellán Alemán, José, Zafrilla Rentero, María Pilar, Montoro-García, Silvia, Mulero, Juana, Pérez Garrido, Alfonso, Leal, Mariano, Guerrero, Lucía, Ramos, Elena, Ruilope, Luis Miguel

“…Nutritional studies focus on traditional cultural models and lifestyles in different countries. The aim of this study was to examine the adherence to the…”
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Combined Structure and Ligand-Based Design of Selective Acetylcholinesterase Inhibitors by Pérez-Sánchez, Horacio, den Haan, Helena, Pérez-Garrido, Alfonso, Peña-García, Jorge, Chakraborty, Sandipan, Erdogan Orhan, Ilkay, Senol Deniz, Fatma Sezer, Villalgordo, José Manuel

“…Acetylcholinesterase is a prime target for therapeutic intervention in Alzheimer’s disease. Acetylcholinesterase inhibitors (AChEIs) are used to improve…”
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Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L by Senol, F. Sezer, Ślusarczyk, Sylwester, Matkowski, Adam, Pérez-Garrido, Alfonso, Girón-Rodríguez, Francisco, Cerón-Carrasco, José P., den-Haan, Helena, Peña-García, Jorge, Pérez-Sánchez, Horacio, Domaradzki, Krzysztof, Orhan, Ilkay Erdogan

“…Cholinesterase inhibition is one of the most treatment strategies against Alzheimer's disease (AD) where metal accumulation is also strongly associated with…”
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Comprehensive Characterization of Linalool-HP-β-Cyclodextrin Inclusion Complexes by Rodríguez-López, María Isabel, Mercader-Ros, María Teresa, Lucas-Abellán, Carmen, Pellicer, José Antonio, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Yáñez-Gascón, María Josefa, Gabaldón, José Antonio, Núñez-Delicado, Estrella

“…The objective of the present study is to obtain linalool- cyclodextrin (CDs) solid complexes for possible applications in the food industry. For this purpose,…”
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Fishing the Targets of Bioactive Compounds from Psidium guajava L. Leaves in the Context of Diabetes by Díaz-de-Cerio, Elixabet, Girón, Francisco, Pérez-Garrido, Alfonso, Pereira, Andreia S P, Gabaldón-Hernández, José Antonio, Verardo, Vito, Segura Carretero, Antonio, Pérez-Sánchez, Horacio

“…L. (guava) leaves have demonstrated their in vitro and in vivo effect against diabetes mellitus (DM). However, there is a lack of literature concerning the…”
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Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway by Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo

“…Rearrangement of the actin cytoskeleton is a prerequisite for carcinoma cells to develop cellular protrusions, which are required for migration, invasion, and…”
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Identification of Kukoamine A, Zeaxanthin, and Clexane as New Furin Inhibitors by Zaragoza-Huesca, David, Martínez-Cortés, Carlos, Banegas-Luna, Antonio Jesús, Pérez-Garrido, Alfonso, Vegara-Meseguer, Josefina María, Peñas-Martínez, Julia, Rodenas, Maria Carmen, Espín, Salvador, Pérez-Sánchez, Horacio, Martínez-Martínez, Irene

“…The endogenous protease furin is a key protein in many different diseases, such as cancer and infections. For this reason, a wide range of studies has focused…”
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2D finger-printing and molecular docking studies identified potent mosquito repellents targeting odorant binding protein 1 by Liggri, Panagiota G.V., Pérez-Garrido, Alfonso, Tsitsanou, Katerina E., Dileep, Kalarickal V., Michaelakis, Antonios, Papachristos, Dimitrios P., Pérez-Sánchez, Horacio, Zographos, Spyros E.

“…Personal protection measures against the mosquitoes like the use of repellents constitute valuable tools in the effort to prevent the transmission of…”
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TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA by Saldi, Tassa K, Ash, Peter EA, Wilson, Gavin, Gonzales, Patrick, Garrido-Lecca, Alfonso, Roberts, Christine M, Dostal, Vishantie, Gendron, Tania F, Stein, Lincoln D, Blumenthal, Thomas, Petrucelli, Leonard, Link, Christopher D

“…Caenorhabditis elegans mutants deleted for TDP‐1, an ortholog of the neurodegeneration‐associated RNA‐binding protein TDP‐43, display only mild phenotypes…”
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Mental Health of Parents as Caregivers of Children with Disabilities: Based on Japanese Nationwide Survey by Yamaoka, Yui, Tamiya, Nanako, Moriyama, Yoko, Sandoval Garrido, Felipe Alfonso, Sumazaki, Ryo, Noguchi, Haruko

“…The number of children with disability is increasing gradually in Japan. Previous researches in other countries have reported that parents as caregivers (CGs)…”
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Two New Parameters Based on Distances in a Receiver Operating Characteristic Chart for the Selection of Classification Models by Pérez-Garrido, Alfonso, Helguera, Aliuska Morales, Borges, Fernanda, Cordeiro, M. Natália D. S, Rivero, Virginia, Escudero, Amalio Garrido

“…There are several indices that provide an indication of different types on the performance of QSAR classification models, being the area under a Receiver…”
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Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors by Helguera, Aliuska Morales, Pérez-Garrido, Alfonso, Gaspar, Alexandra, Reis, Joana, Cagide, Fernando, Vina, Dolores, Cordeiro, M.Natália D.S., Borges, Fernanda

“…Due to their role in the metabolism of monoamine neurotransmitters, MAO-A and MAO-B present a significant pharmacological interest. For instance the inhibitors…”
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Association of mild cognitive impairment and physical activity level in older persons in Chile by Olivares-Tirado, Pedro, Sandoval Garrido, Felipe Alfonso

“…•A low physical activity level was associated with mild cognitive impairment in a representative sample of older persons.•Stratified analysis by sex shows that…”
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The relationship of perceived discrimination in healthcare and future falls among community-dwelling older persons from an English longitudinal cohort [version 1; peer review: awaiting peer review] by Sandoval Garrido, Felipe Alfonso, Bolt, Timothy, Taniguchi, Yuta, Lloyd-Sherlock, Peter

“…Background: The objective of this study is to examine the relation between the perceived discrimination suffered by older adults aged 60 and over during a…”
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Relation of depression with health behaviors and social conditions of dependent community-dwelling older persons in the Republic of Chile by Sandoval Garrido, Felipe Alfonso, Tamiya, Nanako, Lloyd-Sherlock, Peter, Noguchi, Haruko

“…Depressive symptoms are a leading cause of disability and emotional suffering, particularly in old age. However, evidence on depression and old age in…”
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Carvacrol and HP-β-Cyclodextrin Complexes: Extensive Characterization and Potential Cytotoxic Effect in Human Colorectal Carcinoma Cells by Rodríguez-López, María Isabel, Mercader-Ros, María Teresa, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Pellicer, José Antonio, Lucas-Abellán, Carmen, Montoro-García, Silvia, Yáñez-Gascón, María Josefa, Gil-Izquierdo, Ángel, Núñez-Delicado, Estrella, Gabaldón, José Antonio

“…The aim of this study was to obtain solid carvacrol-cyclodextrin (CD) complexes for use in the pharmaceutical industry. To this end, the complexation of…”
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Fuzzy clustering as rational partition method for QSAR by Pérez-Garrido, Alfonso, Girón-Rodríguez, Francisco, Bueno-Crespo, Andrés, Soto, Jesús, Pérez-Sánchez, Horacio, Helguera, Aliuska Morales

“…Various methods are used to make the partition of data sets for QSAR development and model validation. In this work we used a fuzzy minimals partitioning and…”
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Advances in distributed computing with modern drug discovery by Banegas-Luna, Antonio Jesús, Imbernón, Baldomero, Llanes Castro, Antonio, Pérez-Garrido, Alfonso, Cerón-Carrasco, José Pedro, Gesing, Sandra, Merelli, Ivan, D'Agostino, Daniele, Pérez-Sánchez, Horacio

“…Computational chemistry dramatically accelerates the drug discovery process and high-performance computing (HPC) can be used to speed up the most expensive…”
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