Search Results - "Garrett, Lisa J."

CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development by Huang, Bonnie, Gomez-Rodriguez, Julio, Preite, Silvia, Garrett, Lisa J, Harper, Ursula L, Schwartzberg, Pamela L

“…The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to…”
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Bi-allelic TMEM94 Truncating Variants Are Associated with Neurodevelopmental Delay, Congenital Heart Defects, and Distinct Facial Dysmorphism by Stephen, Joshi, Maddirevula, Sateesh, Nampoothiri, Sheela, Burke, John D., Herzog, Matthew, Shukla, Anju, Steindl, Katharina, Eskin, Ascia, Patil, Siddaramappa J., Joset, Pascal, Lee, Hane, Garrett, Lisa. J., Yokoyama, Tadafumi, Balanda, Nicholas, Bodine, Steven P., Tolman, Nathanial J., Zerfas, Patricia M., Zheng, Allison, Ramantani, Georgia, Girisha, Katta M., Rivas, Cecilia, Suresh, Pujar V., Elkahloun, Abdel, Alsaif, Hessa S., Wakil, Salma M., Mahmoud, Laila, Ali, Rehab, Prochazkova, Michaela, Kulkarni, Ashok B., Ben-Omran, Tawfeg, Colak, Dilek, Morris, H. Douglas, Rauch, Anita, Martinez-Agosto, Julian A., Nelson, Stanley F., Alkuraya, Fowzan S., Gahl, William A., Malicdan, May Christine V.

“…Neurodevelopmental disorders (NDD) are genetically and phenotypically heterogeneous conditions due to defects in genes involved in development and function of…”
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Highly Efficient Cpf1-Mediated Gene Targeting in Mice Following High Concentration Pronuclear Injection by Watkins-Chow, Dawn E, Varshney, Gaurav K, Garrett, Lisa J, Chen, Zelin, Jimenez, Erin A, Rivas, Cecilia, Bishop, Kevin S, Sood, Raman, Harper, Ursula L, Pavan, William J, Burgess, Shawn M

“…Cpf1 has emerged as an alternative to the Cas9 RNA-guided nuclease. Here we show that gene targeting rates in mice using Cpf1 can meet, or even surpass, Cas9…”
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A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter by Yocum, Ashley O., Steiner, Laurie A., Seidel, Nancy E., Cline, Amanda P., Rout, Emily D., Lin, Jolinta Y., Wong, Clara, Garrett, Lisa J., Gallagher, Patrick G., Bodine, David M.

“…The human ankyrin-1 gene (ANK1) contains 3 tissue-specific alternative promoters. We have shown previously that the erythroid-specific ankyrin 1 (ANK1E) core…”
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Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties by Chu, Haiyan, McKenna, Mary M., Krump, Nathan A., Zheng, Suilan, Mendelsohn, Laurel, Thein, Swee Lay, Garrett, Lisa J., Bodine, David M., Low, Philip S.

“…Functional studies have shown that the oxygenation state of the erythrocyte regulates many important pathways, including glucose metabolism, membrane…”
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The MFSD12 p.Tyr182His common variant is sufficient to alter mouse agouti coat color by Watkins-Chow, Dawn E, Incao, Arturo A, Rivas, Cecelia, Elliott, Gene, Garrett, Lisa J, Pavan, William J

“…MFSD12 functions as a transmembrane protein required for import of cysteine into melanosomes and lysosomes. The MFSD12 locus has been associated with…”
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Functional Analysis of a Novel cis-Acting Regulatory Region within the Human Ankyrin Gene (ANK-1) Promoter by Laflamme, Karina, Owen, Ashley N., Devlin, Emily E., Yang, Mary Q., Wong, Clara, Steiner, Laurie A., Garrett, Lisa J., Elnitski, Laura, Gallagher, Patrick G., Bodine, David M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of erythrocyte Na+/K+/2Cl− cotransport by an oxygen-switched kinase cascade by Zheng, Suilan, Krump, Nathan A., McKenna, Mary M., Li, Yen-Hsing, Hannemann, Anke, Garrett, Lisa J., Gibson, John S., Bodine, David M., Low, Philip S.

“…Many erythrocyte processes and pathways, including glycolysis, the pentose phosphate pathway (PPP), KCl cotransport, ATP release, Na+/K+-ATPase activity,…”
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Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype by Oliver, Peter L, Chodroff, Rebecca A, Gosal, Amrit, Edwards, Benjamin, Cheung, Amanda F P, Gomez-Rodriguez, Julio, Elliot, Gene, Garrett, Lisa J, Lickiss, Tom, Szele, Francis, Green, Eric D, Molnár, Zoltán, Ponting, Chris P

“…Although long noncoding RNAs (lncRNAs) are proposed to play essential roles in mammalian neurodevelopment, we know little of their functions from their…”
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The COP9 signalosome is vital for timely repair of DNA double-strand breaks by Meir, Michal, Galanty, Yaron, Kashani, Lior, Blank, Michael, Khosravi, Rami, Fernández-Ávila, María Jesús, Cruz-García, Andrés, Star, Ayelet, Shochot, Lea, Thomas, Yann, Garrett, Lisa J, Chamovitz, Daniel A, Bodine, David M, Kurz, Thimo, Huertas, Pablo, Ziv, Yael, Shiloh, Yosef

“…The DNA damage response is vigorously activated by DNA double-strand breaks (DSBs). The chief mobilizer of the DSB response is the ATM protein kinase. We…”
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Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors by Nemeth, Michael J., Cline, Amanda P., Anderson, Stacie M., Garrett-Beal, Lisa J., Bodine, David M.

“…Hmgb3 is an X-linked member of a family of chromatin-binding proteins that is expressed in primitive hematopoietic cells capable of long-term hematopoietic…”
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11-amino acid β-hairpin loop in the cytoplasmic domain of band 3 is responsible for ankyrin binding in mouse erythrocytes by Stefanovic, Marko, Markham, Nicholas O, Parry, Erin M, Garrett-Beal, Lisa J, Cline, Amanda P, Gallagher, Patrick G, Low, Philip S, Bodine, David M

“…The best-studied cytoskeletal system is the inner surface of the erythrocyte membrane, which provides an erythrocyte with the structural support needed to be…”
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Variegated Expression from the Murine Band 3 (AE1) Promoter in Transgenic Mice Is Associated with mRNA Transcript Initiation at Upstream Start Sites and Can Be Suppressed by the Addition of the Chicken β-Globin 5′ HS4 Insulator Element by Frazar, Tiffany F., Weisbein, Jessica L., Anderson, Stacie M., Cline, Amanda P., Garrett, Lisa J., Felsenfeld, Gary, Gallagher, Patrick G., Bodine, David M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis by Kamikubo, Yasuhiko, Hyde, R. Katherine, Zhao, Ling, Alemu, Lemlem, Rivas, Cecilia, Garrett, Lisa J., Liu, P. Paul

“…The C-terminus of CBFβ-SMMHC, the fusion protein produced by a chromosome 16 inversion in acute myeloid leukemia subtype M4Eo, contains domains for…”
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Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals by Simmons, William R, Wain, Lily, Toker, Joseph, Jagadeesh, Jaya, Garrett, Lisa J, Pek, Rini H, Hamza, Iqbal, Bodine, David M

“…In mammals over 65% of the total body iron is located within erythrocytes in the heme moieties of hemoglobin. Iron homeostasis requires iron absorbed from the…”
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Method of Euthanasia Influences the Oocyte Fertilization Rate with Fresh Mouse Sperm by Hazzard, Karen C, Watkins-Chow, Dawn E, Garrett, Lisa J

“…In vitro fertilization (IVF) is used to produce mouse embryos for a variety of reasons. We evaluated the effect of the method of euthanasia on the…”
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Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis by Gallagher, Patrick G, Steiner, Laurie A, Liem, Robert I, Owen, Ashley N, Cline, Amanda P, Seidel, Nancy E, Garrett, Lisa J, Bodine, David M

“…Defects of the ankyrin-1 gene are the most common cause in humans of hereditary spherocytosis, an inherited anemia that affects patients of all ethnic groups…”
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BP1 motif in the human β-globin promoter affects β-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human β-globin gene by Zoueva, Olga P., Garrett, Lisa J., Bodine, David, Rodgers, Griffin P.

“…The binding of the transcription factor BP1 (β protein 1) to its site on the promoter of the adult β-globin gene has a silencing effect on β-globin…”
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Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation by Nemeth, Michael J., Curtis, David J., Kirby, Martha R., Garrett-Beal, Lisa J., Seidel, Nancy E., Cline, Amanda P., Bodine, David M.

“…Hmgb3 is a member of a family of chromatin-binding proteins that can alter DNA structure to facilitate transcription factor binding. We identified the Hmgb3…”
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Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins by Boulanger, Laurent, Sabatino, Denise E, Wong, Ellice Y, Cline, Amanda P, Garrett, Lisa J, Garbarz, Michel, Dhermy, Didier, Bodine, David M, Gallagher, Patrick G

“…alpha-Spectrin is a highly expressed membrane protein critical for the flexibility and stability of the erythrocyte. Qualitative and quantitative defects of…”
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