Search Results - "Garret, Maurice"

Striatal circuit development and its alterations in Huntington's disease by Lebouc, Margaux, Richard, Quentin, Garret, Maurice, Baufreton, Jérôme

“…Huntington's disease (HD) is an inherited neurodegenerative disorder that usually starts during midlife with progressive alterations of motor and cognitive…”
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Targeting parvalbumin-expressing neurons in the substantia nigra pars reticulata restores motor function in parkinsonian mice by Delgado-Zabalza, Lorena, Mallet, Nicolas P., Glangetas, Christelle, Dabee, Guillaume, Garret, Maurice, Miguelez, Cristina, Baufreton, Jérôme

“…The activity of substantia nigra pars reticulata (SNr) neurons, the main output structure of basal ganglia, is altered in Parkinson’s disease (PD). However,…”
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Brain-Endocrine Interactions: A Microvascular Route in the Mediobasal Hypothalamus by Ciofi, Philippe, Garret, Maurice, Lapirot, Olivier, Lafon, Pierrette, Loyens, Anne, Prévot, Vincent, Levine, Jon E

“…Blood-borne hormones acting in the mediobasal hypothalamus, like those controlling food intake, require relatively direct access to target chemosensory neurons…”
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Neurophysiological and Behavioral Effects of Anti-Orexinergic Treatments in a Mouse Model of Huntington’s Disease by Cabanas, Magali, Pistono, Cristiana, Puygrenier, Laura, Rakesh, Divyangana, Jeantet, Yannick, Garret, Maurice, Cho, Yoon H.

“…Huntington’s disease (HD) is associated with sleep and circadian disturbances in addition to hallmark motor and cognitive impairments. Electrophysiological…”
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Alteration of GABAergic neurotransmission in Huntington's disease by Garret, Maurice, Du, Zhuowei, Chazalon, Marine, Cho, Yoon H., Baufreton, Jérôme

“…Summary Hereditary Huntington's disease (HD) is characterized by cell dysfunction and death in the brain, leading to progressive cognitive, psychiatric, and…”
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Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease by Cabanas, Magali, Bassil, Fares, Mons, Nicole, Garret, Maurice, Cho, Yoon H

“…Hereditary Huntington's disease (HD) is associated with progressive motor, cognitive and psychiatric symptoms. A primary consequence of the HD mutation is the…”
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Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington’s disease by Du, Zhuowei, Chazalon, Marine, Bestaven, Emma, Leste-Lasserre, Thierry, Baufreton, Jérôme, Cazalets, Jean-René, Cho, Yoon H, Garret, Maurice

“…Highlights • Reduced GABAergic protein expression in the external globus pallidus of R6/1 mice. • Early reduction of GABAergic neurotransmission and synapses…”
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Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin by Toulmé, Estelle, Soto, Florentina, Garret, Maurice, Boué-Grabot, Eric

“…Although P2X receptors within the central nervous system mediate excitatory ATP synaptic transmission, the identity of central ATP-gated channels has not yet…”
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Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1G93A Lumbar Motoneurons by Milan, Léa, Courtand, Gilles, Cardoit, Laura, Masmejean, Frédérique, Barrière, Grégory, Cazalets, Jean-René, Garret, Maurice, Bertrand, Sandrine S

“…Large cholinergic synaptic terminals known as C-boutons densely innervate the soma and proximal dendrites of motoneurons that are prone to neurodegeneration in…”
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Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s Disease by Du, Zhuowei, Tertrais, Margot, Courtand, Gilles, Leste-Lasserre, Thierry, Cardoit, Laura, Masmejean, Frédérique, Halgand, Christophe, Cho, Yoon H., Garret, Maurice

“…Huntington’s disease (HD) is a neurodegenerative disorder characterized by progressive motor symptoms that are preceded by cognitive deficits and is considered…”
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B02 Early defects in a mouse model of HD by Garret, Maurice, Cho, Yoon H

“…BackgroundMotor symptoms linked to Huntington’s disease (HD) are preceded by a progressive decline of cognitive function, psychiatric disturbances or…”
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Early neurochemical modifications of monoaminergic systems in the R6/1 mouse model of Huntington's disease by Puginier, Emilie, Bharatiya, Rahul, Chagraoui, Abdeslam, Manem, Julien, Cho, Yoon H., Garret, Maurice, De Deurwaerdère, Philippe

“…Huntington's disease (HD) is a rare, autosomal neurodegenerative disease characterized by motor and cognitive impairments appearing in adults. The R6/1 mouse…”
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Agonist-dependent Endocytosis of γ-Aminobutyric Acid Type A (GABAA) Receptors Revealed by a γ2(R43Q) Epilepsy Mutation by Chaumont, Severine, André, Caroline, Perrais, David, Boué-Grabot, Eric, Taly, Antoine, Garret, Maurice

“…GABA-gated chloride channels (GABAARs) trafficking is involved in the regulation of fast inhibitory transmission. Here, we took advantage of a γ2(R43Q) subunit…”
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3-D motion capture for long-term tracking of spontaneous locomotor behaviors and circadian sleep/wake rhythms in mouse by Sourioux, Melissa, Bestaven, Emma, Guillaud, Etienne, Bertrand, Sandrine, Cabanas, Magali, Milan, Lea, Mayo, Willy, Garret, Maurice, Cazalets, Jean-René

“…[Display omitted] •Simultaneous tracking of locomotor movement in tens of freely behaving animals in their home cages.•Does not require separate monitoring…”
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GABAA receptor ɛ-subunit may confer benzodiazepine insensitivity to the caudal aspect of the nucleus tractus solitarii of the rat by Kasparov, Sergey, Davies, Katy A., Patel, Umesh A., Boscan, Pedro, Garret, Maurice, Paton, Julian F. R.

“…Benzodiazepines (BZ) and barbiturates both potentiate chloride currents through GABA A receptors to enhance inhibition. However, unlike barbiturates BZ do not…”
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Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington's disease by Pietropaolo, Susanna, Bellocchio, Luigi, Ruiz-Calvo, Andrea, Cabanas, Magali, Du, Zhuowei, Guzmán, Manuel, Garret, Maurice, Cho, Yoon H.

“…Huntington's disease (HD) is a devastating neurodegenerative disease characterized by a progressive decline in motor abilities, as well as in cognitive and…”
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Differential Alteration in Expression of Striatal GABA A R Subunits in Mouse Models of Huntington's Disease by Du, Zhuowei, Tertrais, Margot, Courtand, Gilles, Leste-Lasserre, Thierry, Cardoit, Laura, Masmejean, Frédérique, Halgand, Christophe, Cho, Yoon H, Garret, Maurice

“…Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive motor symptoms that are preceded by cognitive deficits and is considered…”
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Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion by Robert, Benjamin J.A., Moreau, Maïté M, dos Santos Carvalho, Steve, Barthet, Gael, Racca, Claudia, Bhouri, Mehdi, Quiedeville, Anne, Garret, Maurice, Atchama, Bénédicte, Al Abed, Alice Shaam, Guette, Christelle, Henderson, Deborah J, Desmedt, Aline, Mulle, Christophe, Marighetto, Aline, Montcouquiol, Mireille, Sans, Nathalie

“…The organization of spatial information, including pattern completion and pattern separation processes, relies on the hippocampal circuits, yet the molecular…”
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Alteration of GABA ergic neurotransmission in Huntington's disease by Garret, Maurice, Du, Zhuowei, Chazalon, Marine, Cho, Yoon H., Baufreton, Jérôme

“…Hereditary Huntington's disease ( HD ) is characterized by cell dysfunction and death in the brain, leading to progressive cognitive, psychiatric, and motor…”
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Cross-talk between P2X4 and γ-Aminobutyric Acid, Type A Receptors Determines Synaptic Efficacy at a Central Synapse by Jo, Young-Hwan, Donier, Emmanuelle, Martinez, Audrey, Garret, Maurice, Toulmé, Estelle, Boué-Grabot, Eric

“…The essence of neuronal function is to generate outputs in response to synaptic potentials. Synaptic integration at postsynaptic sites determines neuronal…”
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