Search Results - "Garrait, Ghislain"
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Organogel Nanoparticles as a New Way to Improve Oral Bioavailability of Poorly Soluble Compounds
Published in Pharmaceutical research (01-06-2020)“…Purpose The aim of the study was to evaluate organogel nanoparticles as a lipophilic vehicle to increase the oral bioavailability of poorly soluble compounds…”
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Fabrication of Acrylonitrile-Butadiene-Styrene Nanostructures with Anodic Alumina Oxide Templates, Characterization and Biofilm Development Test for Staphylococcus epidermidis
Published in PloS one (18-08-2015)“…Medical devices can be contaminated by microbial biofilm which causes nosocomial infections. One of the strategies for the prevention of such microbial…”
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Evaluation of the Antimicrobial Activity of a Formulation Containing Ascorbic Acid and Eudragit FS 30D Microparticles for the Controlled Release of a Curcumin–Boric Acid Solid Dispersion in Turkey Poults Infected with Salmonella enteritidis: A Therapeutic Model
Published in International journal of molecular sciences (10-11-2023)“…The selection of components within a formulation or for treatment must stop being arbitrary and must be focused on scientific evidence that supports the…”
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4
Development and Stability of a New Formulation of Pentobarbital Suppositories for Paediatric Procedural Sedation
Published in Pharmaceutics (24-02-2023)“…Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred…”
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Micelle dynamic simulation and physicochemical characterization of biorelevant media to reflect gastrointestinal environment in fasted and fed states
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2014)“…•Characterization of biorelevant media and comparison to in vivo data.•Incorporation of fatty material in biorelevant media to simulate fed state.•Molecular…”
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Gastrointestinal Absorption and Urinary Excretion of trans-Cinnamic and p-Coumaric Acids in Rats
Published in Journal of agricultural and food chemistry (19-04-2006)“…trans-Cinnamic acid (CIN) and p-coumaric acid (COU) are ingested by humans in their diet. While the metabolism and health benefits of CIN have been widely…”
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7
Whey protein mucoadhesive properties for oral drug delivery: Mucin–whey protein interaction and mucoadhesive bond strength
Published in Colloids and surfaces, B, Biointerfaces (01-12-2015)“…[Display omitted] •Mucoadhesion of whey proteins were studied by interaction with mucin.•Whey proteins exhibited chemical interaction with mucin at acidic…”
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Food Chemicals Disrupt Human Gut Microbiota Activity And Impact Intestinal Homeostasis As Revealed By In Vitro Systems
Published in Scientific reports (20-07-2018)“…Growing evidence indicates that the human gut microbiota interacts with xenobiotics, including persistent organic pollutants and foodborne chemicals. The…”
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9
Self-assembly of β-lactoglobulin and egg white lysozyme as a potential carrier for nutraceuticals
Published in Food chemistry (15-04-2015)“…•βlg and lysozyme of opposite charge self-assembled to form microspheres.•The βlg/lysozyme microspheres encapsulated D3 at an efficiency of 90.8±4.8%.•The…”
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10
Development and characterization of novel fast-dissolving pentobarbital suppositories for pediatric procedural sedation and comparison with lipophilic formulations
Published in European journal of pharmaceutics and biopharmaceutics (01-11-2024)“…[Display omitted] For pediatric radiological procedures (RP), pentobarbital sodium (PNa) can be used orally or rectally to replace intravenous anesthesia…”
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11
A prebiotic matrix for encapsulation of probiotics: physicochemical and microbiological study
Published in Journal of microencapsulation (02-01-2016)“…This work aims to develop an encapsulated oral-synbiotic supplement by studying the effect of adding inulin in alginate beads and observing its ability to…”
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Retrograded starch/pectin coated gellan gum-microparticles for oral administration of insulin: A technological platform for protection against enzymatic degradation and improvement of intestinal permeability
Published in European journal of pharmaceutics and biopharmaceutics (01-02-2018)“…[Display omitted] Gellan gum microparticles coated with colon-specific films based on retrograded starch and pectin was developed for enhancing the oral…”
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13
Development of a novel drug delivery system: chitosan nanoparticles entrapped in alginate microparticles
Published in Journal of microencapsulation (01-01-2014)“…Abstract A novel carrier using chitosan nanoparticles entrapped into alginate microparticles is proposed for protecting molecules of interest from degradation…”
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14
Food protein-based microspheres for increased uptake of vitamin D3
Published in Food chemistry (15-04-2015)“…•Food proteins βlg/lysozyme microspheres improved the stability of D3.•The βlg/lysozyme microspheres enhanced the bioavailability of D3in vivo.•The water…”
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15
Improved bioavailability of vitamin D3 using a β-lactoglobulin-based coagulum
Published in Food chemistry (01-04-2015)“…•D3 was successfully encapsulated within a water soluble βlg-based scaffold.•Encapsulation efficiency of D3 in the βlg-based coagulum was…”
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Increased stability and protease resistance of the β-lactoglobulin/vitamin D3 complex
Published in Food chemistry (15-02-2014)“…•The stability of vitamin D3 was significantly improved upon complexation with βlg.•The resistance of βlg to proteases in the intestines was improved.•The…”
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Molecular and biopharmaceutical investigation of alginate-inulin synbiotic coencapsulation of probiotic to target the colon
Published in Journal of microencapsulation (17-02-2017)“…Colon targeting, as a site-specific delivery for oral formulation, remains a major challenge, especially for sensitive bioactive components such as therapeutic…”
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18
Denatured Whey Protein Powder as a New Matrix Excipient: Design and Evaluation of Mucoadhesive Tablets for Sustained Drug Release Applications
Published in Pharmaceutical research (01-02-2017)“…Purpose In earlier study, we proposed denatured whey protein (DWP) powder obtained by atomization as a new excipient to promote oral drug delivery. In this…”
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Evaluation of the Antimicrobial Activity of a Formulation Containing Ascorbic Acid and Eudragit FS 30D Microparticles for the Controlled Release of a Curcumin–Boric Acid Solid Dispersion in Turkey Poults Infected with ISalmonella enteritidis/I: A Therapeutic Model
Published in International journal of molecular sciences (01-11-2023)“…The selection of components within a formulation or for treatment must stop being arbitrary and must be focused on scientific evidence that supports the…”
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20
Atomization of denatured whey proteins as a novel and simple way to improve oral drug delivery system properties
Published in International journal of biological macromolecules (01-12-2017)“…In the sphere of drug delivery, denatured whey protein (DWP) has in recent times gained press. However, to date, no scalable and affordable dosage form has…”
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