Search Results - "Garoff, H."

Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure by Wu, Shang-Rung, Löving, Robin, Lindqvist, Birgitta, Hebert, Hans, Koeck, Philip J. B., Sjöberg, Mathilda, Garoff, Henrik, Goff, Stephen P.

“…The HIV-1 spike is a trimer of the transmembrane gp41 and the peripheral gp120 subunit pair. It is activated for virus–cell membrane fusion by binding…”
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Semliki Forest virus biodistribution in tumor-free and 4T1 mammary tumor-bearing mice: a comparison of transgene delivery by recombinant virus particles and naked RNA replicon by Vasilevska, J, Skrastina, D, Spunde, K, Garoff, H, Kozlovska, T, Zajakina, A

“…Semliki Forest virus (SFV) vectors are promising tools for cancer gene therapy because they ensure a high level of transgene expression and a rapid and strong…”
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Recombinant Semliki Forest virus vectors encoding hepatitis B virus small surface and pre-S1 antigens induce broadly reactive neutralizing antibodies by Niedre-Otomere, B., Bogdanova, A., Skrastina, D., Zajakina, A., Bruvere, R., Ose, V., Gerlich, W. H., Garoff, H., Pumpens, P., Glebe, D., Kozlovska, T.

“…Most hepatitis B virus (HBV) vaccines consist of viral small surface (S) protein subtype adw2 expressed in yeast cells. In spite of good efficacy, HBV‐genotype…”
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Turning of the receptor-binding domains opens up the murine leukaemia virus Env for membrane fusion by Wu, Shang-Rung, Sjöberg, Mathilda, Wallin, Michael, Lindqvist, Birgitta, Ekström, Maria, Hebert, Hans, Koeck, Philip J B, Garoff, Henrik

“…The activity of the membrane fusion protein Env of Moloney mouse leukaemia virus is controlled by isomerization of the disulphide that couples its…”
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In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release by LILJESTROM, P, LUSA, S, HUYLEBROECK, D, GAROFF, H

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Internally located cleavable signal sequences direct the formation of Semliki Forest virus membrane proteins from a polyprotein precursor by LILJESTROÊM, P, GAROFF, H

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Membrane fusion of Semliki Forest virus in a model system: correlation between fusion kinetics and structural changes in the envelope glycoprotein by Bron, R., Wahlberg, J.M., Garoff, H., Wilschut, J.

“…This paper presents a kinetic analysis of low‐pH‐induced fusion of Semliki Forest virus (SFV) with cholesterol‐containing unilamellar lipid vesicles…”
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A tyrosine‐based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding by Zhao, H., Lindqvist, B., Garoff, H., Bonsdorff, C.H., Liljeström, P.

“…The budding of enveloped viruses from cellular membranes is believed to be dependent on the specific interaction between transmembrane spike proteins and…”
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Membrane fusion of Semliki Forest virus involves homotrimers of the fusion protein by WAHLBERG, J. M, BRON, R, WILSCHUT, J, GAROFF, H

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6: Viable HHV-6A viral particles purified with iodixanol gradients by Ahlqvist, J., Hammarstedt, M., Jacobson, S., Garoff, H., Fogdell-Hahn, A.

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Spike protein-nucleocapsid interactions drive the budding of alphaviruses by Suomalainen, M, Liljeström, P, Garoff, H

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Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus by SUOMALAINEN, M, GAROFF, H

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Preformed cytoplasmic nucleocapsids are not necessary for alphavirus budding by Forsell, K., Griffiths, G., Garoff, H.

“…According to the present model for assembly of alphaviruses, e.g. Semliki Forest virus (SFV), the viral genome is first encapsidated into a nucleocapsid (NC)…”
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The heterodimeric association between the membrane proteins of Semliki Forest virus changes its sensitivity to low pH during virus maturation by WAHLBERG, J. M, BOERE, W. A. M, GAROFF, H

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Production of Infectious Recombinant Moloney Murine Leukemia Virus Particles in BHK Cells Using Semliki Forest Virus-Derived RNA Expression Vectors by Li, Ke-Jun, Garoff, Henrik

“…We describe a heterologous, Semliki Forest virus (SFV)-driven packaging system for the production of infectious recombinant Moloney murine leukemia virus…”
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Processing of the Semliki Forest virus structural polyprotein: role of the capsid protease by MELANCON, P, GAROFF, H

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Targeting of Moloney Murine Leukemia Virus Gag Precursor to the Site of Virus Budding by Suomalainen, Maarit, Hultenby, Kjell, Garoff, Henrik

“…Retrovirus Moloney murine leukemia virus (M-MuLV) matures by budding at the cell surface. Central to the budding process is the myristoylated viral core…”
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Structure-function relation of the NH2-terminal domain of the Semliki Forest virus capsid protein by Forsell, K, Suomalainen, M, Garoff, H

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Membrane fusion of Semliki Forest virus in a model system : correlation between fusion kinetics and structural changes in the envelope glycoprotein by BRON, R, WAHLBERG, J. M, GAROFF, H, WILSCHUT, J

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Membrane protein lateral interactions control Semliki Forest virus budding by Ekström, M., Liljeström, P., Garoff, H.

“…Semliki Forest virus, SFV, directs the synthesis of two membrane proteins, p62 and E1, which form a p62E1 heterodimer in the endoplasmic reticulum. After being…”
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