Search Results - "Garofalo, Kevin"
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Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-2015)“…Despite the beneficial therapeutic effects of intravenous immunoglobulin (IVIg) in inflammatory diseases, consistent therapeutic efficacy and potency remain…”
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Lost in hostile lands: moths of conservation concern in cultivated and suburban areas of south Italy
Published in Nature Conservation (21-12-2023)“…Cultivated and suburban areas are usually considered unfavourable to the vulnerable components of biodiversity and regarded as not interesting from a…”
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3
Equivalent Gene Expression Profiles between Glatopa™ and Copaxone
Published in PloS one (16-10-2015)“…Glatopa™ is a generic glatiramer acetate recently approved for the treatment of patients with relapsing forms of multiple sclerosis. Gene expression profiling…”
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4
Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1
Published in The Journal of neuroscience (18-11-2009)“…Mutations in the SPTLC1 subunit of serine palmitoyltransferase (SPT) cause an adult-onset, hereditary sensory, and autonomic neuropathy type I (HSAN1). We…”
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Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1
Published in The Journal of clinical investigation (01-12-2011)“…Hereditary sensory and autonomic neuropathy type 1 (HSAN1) causes sensory loss that predominantly affects the lower limbs, often preceded by hyperpathia and…”
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6
Abstract 561: Discovery of a potential best-in-class anti-CD38 therapeutic utilizing Fc multimerization
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…CD38 targeting antibodies are at different phases of clinical development, with daratumumab already approved as monotherapy and in combination with standards…”
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Abstract 3244: Improved Fc-mediated effector functions by an anti-CTLA-4 multivalent Fc agent
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Numerous therapeutic monoclonal antibodies (mAbs) rely on antibody-dependent cell cytotoxicity (ADCC), antibody-dependent cell phagocytosis (ADCP) and…”
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Equivalent Gene Expression Profiles between Glatopa.sup.[TM] and Copaxone.sup.
Published in PloS one (16-10-2015)“…Glatopa.sup.[TM] is a generic glatiramer acetate recently approved for the treatment of patients with relapsing forms of multiple sclerosis. Gene expression…”
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Journal Article -
9
Oral L-serine supplementation reduces production of neurotoxic deoxyspingolipids in mice and humans with hereditary sensory autonomic neuropathy type1
Published in The Journal of clinical investigation (01-12-2011)“…Hereditary sensory and autonomic neuropathy type 1 (HSAN1) causes sensory loss that predominantly affects the lower limbs, often preceded by hyperpathia and…”
Get full text
Journal Article -
10
Equivalent Gene Expression Profiles between GlatopaTM and Copaxone registered : e0140299
Published in PloS one (01-10-2015)“…GlatopaTM is a generic glatiramer acetate recently approved for the treatment of patients with relapsing forms of multiple sclerosis. Gene expression profiling…”
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