Search Results - "Garnett, WR"

Clinical Pharmacology of Topiramate: A Review by Garnett, William R.

“…Clinical success with an antiepileptic drug (AED) depends primarily on its efficacy and tolerability. Clinicians also need to have a basic understanding of an…”
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Clinical Implications of Drug Interactions with Coxibs by Garnett, William R.

“…Nonsteroidal antiinflammatory drugs (NSAIDs) often are prescribed to patients who are taking concomitant drugs. Cyclooxygenase (COX)‐2 inhibitors (coxibs)…”
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Treatment of Crohn's disease with infliximab by Garnett, WR, Yunker, N

“…The role of infliximab in managing Crohn's disease (CD) is described. CD is characterized by chronic transmural inflammation at various sites of the…”
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Optimizing Antiepileptic Drug Therapy in the Elderly by Garnett, William R

“…OBJECTIVE To review and evaluate the medical literature concerning antiepileptic drug (AED) therapy in elderly patients. DATA SOURCES A MEDLINE search…”
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Lamotrigine: pharmacokinetics by Garnett, W R

“…The pharmacokinetics of lamotrigine have been studied in single and multiple dose studies in animals, normal volunteers, and patients with epilepsy…”
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Antiepileptic Drug Treatment: Outcomes and Adherence by Garnett, William R.

“…The goal in treating patients with epilepsy is a cost‐effective approach to the elimination of seizures or a reduction in their number and frequency while…”
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Carbamazepine extended-release capsules vs. oxcarbazepine: computer simulations of the effect of missed doses on drug plasma concentrations by Ahmad, Alaa, Garnett, William R.

“…ABSTRACT Objective: Plasma concentrations of antiepileptic drugs (AEDs) can vary and are not always an indication of clinical utility. However, adverse event…”
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History of Acid Suppression: Focus on the Hospital Setting by Garnett, William R.

“…In the hospital setting, prophylactic acid suppression is an important part of care for many critically ill patients. It may also prevent rebleeding in…”
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Introduction: New Concepts in Acid Suppression for the Hospitalized Patient by Garnett, William R.

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Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors by Garnett, W R

“…Drug-drug, drug-food, and drug-disease interactions involving hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are reviewed. The four available…”
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Patterns of care, outcomes, and direct health plan costs of antiepileptic therapy: a pharmacoeconomic analysis of the available carbamazepine formulations by Garnett, William R., Gilbert, Thomas D., O'Connor, Paul

“…Abstract Although generic formulations of immediate-release carbamazepine (IR-CBZ) are available, extended-release delivery systems may offer important…”
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Lack of a Clinically Significant Effect of Zonisamide on Phenytoin Steady-State Pharmacokinetics in Patients With Epilepsy by Levy, René H., Ragueneau-Majlessi, Isabelle, Garnett, William R., Schmerler, Michael, Rosenfeld, William, Shah, Jaymin, Pan, Wei-Jian

“…This study was designed to measure the effect of the addition of zonisamide on phenytoin pharmacokinetics under steady‐state conditions in patients with…”
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Considerations for long-term use of proton-pump inhibitors by Garnett, WR

“…The safety of proton-pump inhibitors (PPIs) for long-term use is reviewed. PPIs are being used with increasing frequency to inhibit secretion of gastric acid…”
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Effect of telephone follow-up on medication compliance by Garnett, W R, Davis, L J, McKenney, J M, Steiner, K C

“…This study compared the effectiveness, in improving patient compliance with a 10-14 day course of antibiotic therapy, of the following two strategies: (1) a…”
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Simulated fluctuations in plasma drug concentrations for patients receiving oxcarbazepine or carbamazepine extended-release capsules by Ahmad, Alaa, Garnett, William R

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Tolerability and effects on quality of life of twice-daily extended-release carbamazepine in adults with seizure disorders: An open-label, 12- to 36-month continuation study by Edward Hogan, R, Garnett, William R, Thadani, Vijay M

“…Background: An earlier 6-month, multicenter, open-label study in patients with complex partial seizures found that a switch from multiple daily doses of…”
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The use of Monte Carlo simulations to study the effect of poor compliance on the steady state concentrations of valproic acid following administration of enteric-coated and extended release divalproex sodium formulations by Ahmad, Alaa M., Douglas Boudinot, F., Barr, William H., Reed, Ronald C., Garnett, William R.

“…Divalproex sodium extended‐release (Depakote® ER) is a once daily (QD) formulation for valproic acid that was developed to improve patient compliance and to…”
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Simulation of the effect of patient nonadherence on plasma concentrations of carbamazepine from twice-daily extended-release capsules by Garnett, William R., McLean, Angus M., Zhang, Yuxin, Clausen, Susan, Tulloch, Simon J.

“…SUMMARY Objective: Carbamazepine (CBZ) effectively treats simple, complex, and secondarily generalized partial seizures. Computer simulations were carried out…”
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A Review of Current Clinical Findings With Fluvastatin by Garnett, William R.

“…Fluvastatin, the newest member of the class of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, is structurally different from the fungal…”
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Pharmacist Impact on Posttraumatic Seizure Prophylaxis in Patients with Head Injury by Brophy, Gretchen M., Tesoro, Eljim P., Schrote, Gretchen L., Garnett, William R.

“…Phenytoin is the most commonly administered antiepileptic agent for the prevention of early (≤ 7 days) posttraumatic seizures. Use of the agent, however,…”
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