Search Results - "Garner, Warren L."
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Matrix metalloproteinase-9 delays wound healing in a murine wound model
Published in Surgery (01-02-2010)“…Background Metalloproteinase-9 (MMP-9) is a type IV collagenase found at elevated levels in chronic wounds. As wounds heal, MMP-9 diminishes. In this study, we…”
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American Burn Association consensus conference to define sepsis and infection in burns
Published in Journal of burn care & research (01-11-2007)“…Because of their extensive wounds, burn patients are chronically exposed to inflammatory mediators. Thus, burn patients, by definition, already have "systemic…”
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Integra in Lower Extremity Reconstruction after Burn Injury
Published in Plastic and reconstructive surgery (1963) (01-04-2008)“…Standard care for lower extremity injuries with exposed bone or tendon is vascularized tissue transfer. In patients with deep and extensive burn injuries,…”
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Delayed‐onset thrombocytopenia in a pediatric burn patient
Published in American journal of hematology (01-09-2016)Get full text
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Essential Role of Matrix Metalloproteinases in Interleukin-1-induced Myofibroblastic Activation of Hepatic Stellate Cell in Collagen
Published in The Journal of biological chemistry (06-02-2004)“…Located within the perisinusoidal space and surrounded by extracellular matrix, hepatic stellate cells (HSC) undergo phenotypic trans-differentiation called…”
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Management of Vulvovaginal Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Published in Obstetrics and gynecology (New York. 1953) (12-09-2024)“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is an autoimmune process resulting in painful epidermal sloughing that can involve the vulva…”
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Epithelial to Mesenchymal Transition in Human Skin Wound Healing Is Induced by Tumor Necrosis Factor-α through Bone Morphogenic Protein-2
Published in The American journal of pathology (01-05-2010)“…Epithelial-mesenchymal transition (EMT), characterized by loss of epithelial adhesion and gain of mesenchymal features, is an important mechanism to empower…”
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TNF-α Suppresses α-Smooth Muscle Actin Expression in Human Dermal Fibroblasts: An Implication for Abnormal Wound Healing
Published in Journal of investigative dermatology (01-11-2007)“…Abnormal wound healing encompasses a wide spectrum, from chronic wounds to hypertrophic scars. Both conditions are associated with an abnormal cytokine profile…”
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Combination therapy: Etanercept and intravenous immunoglobulin for the acute treatment of Stevens-Johnson syndrome/toxic epidermal necrolysis
Published in Burns (01-11-2019)“…•Etanercept with IVIg and supportive care may improve outcomes compared to IVIg and supportive care alone.•There were no differences in complications between…”
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Venous Thromboembolism Chemoprophylaxis in Burn Patients: A Literature Review and Single-Institution Experience
Published in Journal of burn care & research (03-02-2021)“…Hospitalized burn patients meet the criteria for Virchow's triad (endothelial damage, hypercoagulability, and stasis), predisposing them to venous…”
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Re: Combination therapy for Toxic Epidermal Necrolysis: It is time for anti-TNFa biologics comparison
Published in Burns (01-02-2020)Get full text
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The State of Burn Care Training During Plastic Surgery Residency
Published in Annals of plastic surgery (01-08-2020)“…INTRODUCTIONThere is an ongoing shortage of burn specialists, and workforce reports suggest possible hurdles attracting plastic surgeons into burn care. The…”
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The Impact of Peer Support Group Programs on Psychosocial Outcomes for Burn Survivors and Caregivers: A Review of the Literature
Published in Journal of burn care & research (04-08-2021)“…Abstract Peer support group programs are often recommended for burn survivors as a way to facilitate their psychosocial recovery and reintegration into the…”
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Small Pediatric Burns Can Be Safely Managed on an Outpatient Basis
Published in Journal of burn care & research (23-09-2020)“…Abstract American Burn Association (ABA) guidelines recommend that all pediatric burns be transferred to a burn center if their presenting hospital lacks the…”
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Interleukin-8 levels and activity in delayed-healing human thermal wounds
Published in Wound repair and regeneration (01-05-2000)“…There are numerous causes for slow or delayed wound healing. Because slowly healing wounds are often inflamed, we quantitated the inflammatory chemokine,…”
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Acute Burns
Published in Plastic and reconstructive surgery (1963) (01-05-2008)“…After studying this article, the participant should be able to: 1. Describe the pathophysiology of burn injury. 2. Identify patient criteria for transfer to a…”
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The Impact of No Next of Kin Decision Makers on End-of-Life Care
Published in Journal of burn care & research (03-02-2021)“…For critically ill burn patients without a next of kin, the medical team is tasked with becoming the surrogate decision maker. This poses ethical and legal…”
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The Homelessness Crisis and Burn Injuries: A Cohort Study
Published in Journal of burn care & research (03-07-2020)“…Abstract The United States is facing a growing homelessness crisis. We characterize the demographics and outcomes of homeless patients who sustain burn injury…”
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Proteolytic Activation of Matrix Metalloproteinase-9 in Skin Wound Healing Is Inhibited by α-1-Antichymotrypsin
Published in Journal of investigative dermatology (01-09-2008)“…An excessive amount of matrix metalloproteinase-9 (MMP-9) has been well documented in inflammatory diseases, including chronic wounds and cancers. Secreted as…”
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Hypoglycemic episodes predict length of stay in patients with acute burns
Published in Journal of critical care (01-08-2021)“…Hypoglycemic episodes are associated with worse hospital outcomes. All adult patients admitted to our burn center from 2015 to 2019 were retrospectively…”
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