Search Results - "Garner, Krista L"
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Maternal Engineered Nanomaterial Inhalation During Gestation Disrupts Vascular Kisspeptin Reactivity
Published in Toxicological sciences (01-06-2019)“…Abstract Maternal engineered nanomaterial (ENM) inhalation is associated with uterine vascular impairments and endocrine disruption that may lead to altered…”
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Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations
Published in Particle and fibre toxicology (09-03-2022)“…Pregnancy is associated with many rapid biological adaptations that support healthy development of the growing fetus. One of which is critical to fetal health…”
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Whole-body inhalation of nano-sized carbon black: a surrogate model of military burn pit exposure
Published in BMC research notes (11-08-2022)“…Chronic multisymptom illness (CMI) is an idiopathic disease affecting thousands of U.S. Veterans exposed to open-air burn pits emitting aerosolized particulate…”
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Composable Microfluidic Plates (cPlate): A Simple and Scalable Fluid Manipulation System for Multiplexed Enzyme-Linked Immunosorbent Assay (ELISA)
Published in Analytical chemistry (Washington) (26-01-2021)“…Enzyme-linked immunosorbent assay (ELISA) is the gold standard method for protein biomarkers. However, scaling up ELISA for multiplexed biomarker analysis is…”
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Maternal titanium dioxide nanomaterial inhalation exposure compromises placental hemodynamics
Published in Toxicology and applied pharmacology (15-03-2019)“…The fetal consequences of gestational engineered nanomaterial (ENM) exposure are unclear. The placenta is a barrier protecting the fetus and allowing transfer…”
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Nanomaterial Inhalation During Pregnancy Alters Systemic Vascular Function in a Cyclooxygenase-Dependent Manner
Published in Toxicological sciences (28-07-2022)“…Abstract Pregnancy requires rapid adaptations in the uterine microcirculation to support fetal development. Nanomaterial inhalation is associated with…”
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Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM
Published in Nanotoxicology (01-08-2021)“…Maternal engineered nanomaterial (ENM) exposure during gestation has been associated with negative long-term effects on cardiovascular health in progeny. Here,…”
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Maternal Nanomaterial Inhalation Exposure: Critical Gestational Period in the Uterine Microcirculation is Angiotensin II Dependent
Published in Cardiovascular toxicology (01-02-2022)“…Maternal inhalation exposure to engineered nanomaterials (ENM) has been associated with microvascular dysfunction and adverse cardiovascular responses…”
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Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO 2 nanoparticle inhalation exposure
Published in Environmental science. Advances (09-05-2023)“…Nano-titanium dioxide (nano-TiO ) is a widely used nanomaterial found in several industrial and consumer products, including surface coatings, paints,…”
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Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO2 nanoparticle inhalation exposure
Published in Environmental science. Advances (09-05-2023)“…Nano-titanium dioxide (nano-TiO2) is a widely used nanomaterial found in several industrial and consumer products, including surface coatings, paints,…”
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Abstract 5778: A three-dimensional RAFT™ co-culture as advanced model for breast cancer drug discovery
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract High-throughput screening (HTS) using two-dimensional (2D) cell culture models (2D HTS) is essential for rapid identification of drug candidates from…”
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Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO nanoparticle inhalation exposure
Published in Environmental science. Advances (09-05-2023)“…Nano-titanium dioxide (nano-TiO 2 ) is a widely used nanomaterial found in several industrial and consumer products, including surface coatings, paints,…”
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