Search Results - "Garner, H R"

High-depth, high-accuracy microsatellite genotyping enables precision lung cancer risk classification by Velmurugan, K R, Varghese, R T, Fonville, N C, Garner, H R

“…There remains a large discrepancy between the known genetic contributions to cancer and that which can be explained by genomic variants, both inherited and…”
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Evaluation of microsatellite variation in the 1000 Genomes Project pilot studies is indicative of the quality and utility of the raw data and alignments by McIver, L.J., Fondon, J.W., Skinner, M.A., Garner, H.R.

“…We performed an analysis of global microsatellite variation on the two kindreds sequenced at high depth (~ 20×–60×) in the 1000 Genomes Project pilot studies…”
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Genome-wide responses to mitochondrial dysfunction by Epstein, C B, Waddle, J A, Hale, 4th, W, Davé, V, Thornton, J, Macatee, T L, Garner, H R, Butow, R A

“…Mitochondrial dysfunction can lead to diverse cellular and organismal responses. We used DNA microarrays to characterize the transcriptional responses to…”
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High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints by WISTUBA, I. I, BEHRENS, C, LERMAN, M. I, LAM, S, GAZDAR, A. F, MINNA, J. D, VIRMANI, A. K, MELE, G, MILCHGRUB, S, GIRARD, L, FONDON, J. W, GARNER, H. R, MCKAY, B, LATIF, F

“…Allele loss involving chromosome arm 3p is one of the most frequent and earliest known genetic events in lung cancer pathogenesis and may affect several…”
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A long AAAG repeat allele in the 5′ UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells by Galindo, C. L., McCormick, J. F., Bubb, V. J., Abid Alkadem, D. H., Li, Long-Shan, McIver, L. J., George, A. C., Boothman, D. A., Quinn, J. P., Skinner, M. A., Garner, H. R.

“…We sequenced the 5′ UTR of the estrogen-related receptor gamma gene ( ERR -γ) in ~500 patient and volunteer samples and found that longer alleles of the (AAAG)…”
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Heuristics for identification of acronym-definition patterns within text: towards an automated construction of comprehensive acronym-definition dictionaries by Wren, J D, Garner, H R

“…To develop an automated, accurate and scalable method by which acronym-definition pairs can be identified within text. Its primary advantage is in enabling…”
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Global Microsatellite Content Distinguishes Humans, Primates, Animals, and Plants by Galindo, C.L., McIver, L.J., McCormick, J.F., Skinner, M.A., Xie, Y., Gelhausen, R.A., Ng, K., Kumar, N.M., Garner, H.R.

“…Microsatellites are highly mutable, repetitive sequences commonly used as genetic markers, but they have never been studied en masse. Using a custom microarray…”
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Shared relationship analysis: ranking set cohesion and commonalities within a literature-derived relationship network by Wren, Jonathan D., Garner, Harold R.

“…Motivation: There is a general scientific need to be able to identify and evaluate what any given set of ‘objects’ (e.g. genes, phenotypes, chemicals,…”
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Repeat Polymorphisms within Gene Regions: Phenotypic and Evolutionary Implications by Wren, Jonathan D., Forgacs, Eva, Fondon, John W., Pertsemlidis, Alexander, Cheng, Sandra Y., Gallardo, Teresa, Williams, R.S., Shohet, Ralph V., Minna, John D., Garner, Harold R.

“…We have developed an algorithm that predicted 11,265 potentially polymorphic tandem repeats within transcribed sequences. We estimate that 22% (2,207/9,717) of…”
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Combating unethical publications with plagiarism detection services by Garner, H.R., Ph.D

“…Abstract About 3,000 new citations that are highly similar to citations in previously published manuscripts that appear each year in the biomedical literature…”
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Population-scale analysis of human microsatellites reveals novel sources of exonic variation by McIver, L.J., McCormick, J.F., Martin, A., Fondon, J.W., Garner, H.R.

“…Using our microsatellite specific genotyping method, we analyzed tandem repeats, which are known to be highly variable with some recognized as biomarkers…”
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Butorphanol-mediated antinociception in mice: partial agonist effects and mu receptor involvement by Garner, H R, Burke, T F, Lawhorn, C D, Stoner, J M, Wessinger, W D

“…In the present experiments, we characterized the agonist and antagonist effects of butorphanol in mice. In the mouse radiant-heat tail-flick test, the mu…”
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Instrumentation for the Genome Project by Jaklevic, J. M, Garner, H. R, Miller, G. A

“…Much of the recent rapid progress in large-scale genomic sequencing has been driven by the dramatic improvements both in the area of biological protocols and…”
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Association of Extensive Polymorphisms in the SLAM/CD2 Gene Cluster with Murine Lupus by Wandstrat, Amy E., Nguyen, Charles, Limaye, Nisha, Chan, Alice Y., Subramanian, Srividya, Tian, Xiang-Hong, Yim, Young-Sun, Pertsemlidis, Alexander, Garner, Harold R., Morel, Laurence, Wakeland, Edward K.

“…Susceptibility to autoimmunity in B6. Sle1b mice is associated with extensive polymorphisms between two divergent haplotypes of the SLAM/CD2 family of genes…”
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Microsatellite genotyping reveals a signature in breast cancer exomes by McIver, L. J., Fonville, N. C., Karunasena, E., Garner, H. R.

“…Genomic instability at microsatellite loci is a hallmark of many cancers, including breast cancer. However, much of the genomic variation and many of the…”
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Knowledge discovery by automated identification and ranking of implicit relationships by Wren, Jonathan D., Bekeredjian, Raffi, Stewart, Jelena A., Shohet, Ralph V., Garner, Harold R.

“…Motivation: New relationships are often implicit from existing information, but the amount and growth of published literature limits the scope of analysis an…”
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Comparative analysis of the early transcriptome of Brucella abortus – Infected monocyte-derived macrophages from cattle naturally resistant or susceptible to brucellosis by Rossetti, C.A., Galindo, C.L., Everts, R.E., Lewin, H.A., Garner, H.R., Adams, L.G.

“…Brucellosis is a worldwide zoonotic infectious disease that has a significant economic impact on animal production and human public health. We characterized…”
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MarC-V: a spreadsheet-based tool for analysis, normalization, and visualization of single cDNA microarray experiments by Schageman, J J, Basit, M, Gallardo, T D, Garner, H R, Shohet, R V

“…The comprehensive analysis and visualization of data extracted from cDNA microarrays can be a time-consuming and error-prone process that becomes increasingly…”
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PRIMO: A Primer Design Program That Applies Base Quality Statistics for Automated Large-Scale DNA Sequencing by Li, Ping, Kupfer, Kenneth C., Davies, Christopher J., Burbee, David, Evans, Glen A., Garner, Harold R.

“…PRIMO is a computer program that designs walking primers for large-scale DNA sequencing projects. Oligonucleotide primers are predicted automatically, using…”
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Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes by Wren, Jonathan D, Garner, Harold R

“…The etiological origin of type 2 diabetes mellitus (T2DM) has long been controversial. The body of literature related to T2DM is vast and varied in focus,…”
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