Search Results - "Garner, A. L."

Numerical assessments of geometry, proximity and multi-electrode effects on electroporation in mitochondria and the endoplasmic reticulum to nanosecond electric pulses by Baker, C., Willis, A., Milestone, W., Baker, M., Garner, A. L., Joshi, R. P.

“…Most simulations of electric field driven bioeffects have considered spherical cellular geometries or probed symmetrical structures for simplicity. This work…”
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A Multi-Dimensional Child-Langmuir Law with Surface Roughness by Harsha, N.R. Sree, Garner, A. L.

“…The Child-Langmuir (CL) law determines the maximum current density, or space-charge limited current density (SCLCD), for a one-dimensional (1D) planar diode…”
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Electron Cycloidal and Brillouin Flows in a Two-Dimensional Planar Crossed-Field Gap by Zhu, X., Luginsland, J. W., Browning, J., Garner, A. L.

“…In crossed-field devices, Brillouin flow is regarded as the prevalent equilibrium flow 1 . One-dimensional (1-D) theory and particle-in-cell (PIC) simulations…”
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Techniques for Determining Space-Charge Limited Current for Nonplanar Crossed-Field Diodes by Wright, J. K., Harsha, N.R. S., Garner, A. L.

“…Calculating the space-charge-limited current (SCLC) is critical for numerous applications, including high-power microwaves (HPM), electric thrusters, and nano…”
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Theoretical Analysis of Microwave Breakdown for Microscale Gaps by Mahajanl, S., Loveless, A. M., Semnani, A., Ayyaswamy, V., Garner, A. L.

“…While DC gas breakdown is traditionally driven by Townsend avalanche (TA), the strong electric fields that arise for microscale gaps at non-vacuum pressures…”
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Simulations of Permittivity and Permeability of Nonlinear Materials by Loveless, A., Mannodi-Kanakkithodi, A. K., Crawford, T. D., Sengupta, S., Garner, A. L.

“…Nonlinear transmission lines (NLTLs) provide a low-cost, all solid-state design for generating high-power microwaves 1 . Several studies have used lumped…”
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Space-Charge-Limited Current in Finite Concentric Cylindrical Diodes by Sree Harsha, N.R., Watrous, J., Garner, A. L.

“…Characterizing space-charge-limited current (SCLC), the maximum current that can flow in the steady-state operation of a diode, is important for numerous…”
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Secondary Electron Emission Study In L-4953 Crossed-Field Amplifier by Manker, N.K., Pearlman, M., Watrous, J., Roark, C., Smithe, D., Garner, A. L., Worthington, M., Browning, J.

“…The L-4953 Cross-Field Amplifier (CFA) is a high-power (≈5MW), moderate gain (11.2 dB), pulsed, L-band (1.28 to 1.35 GHz), reentrant, backward wave, thermionic…”
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Theoretical Analysis of Electron Trajectories in a Collisional Crossed-Field Gap by Komrska, A. M., Breen, L. I., Loveless, A. M., Cartwright, K. L., Garner, A. L.

“…Many applications, including Hall-effect thrusters and high-power microwaves, involve the application of a magnetic field orthogonal to the electric field…”
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Incorporating Collisions into the Limiting Current of a Crossed-Field Gap by Breen, L. I., Loveless, A. M., Komrska, A. M., Cartwright, K. L., Garner, A. L.

“…Crossed-field devices, which have magnetic fields perpendicular to the electric field across the gap, are used for numerous high-power applications, such as…”
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A Simulation Study of the Gain Limits of a Crossed-Field Amplifier by Pearlman, M., Watrous, J., Smithe, D., Yue, A., Garner, A. L., Worthington, M., Browning, J.

“…The recently available design specifications for the L-4953 crossed-field amplifier (CFA) from Stellant Systems provides an excellent high-power CFA simulation…”
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Implications of a simple mathematical model to cancer cell population dynamics by Garner, A. L., Lau, Y. Y., Jordan, D. W., Uhler, M. D., Gilgenbach, R. M.

“…  Recent research in cancer progression and treatment indicates that many forms of cancer arise from the development of a small subpopulation of abnormal…”
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Time domain dielectric spectroscopy measurements of HL-60 cell suspensions after microsecond and nanosecond electrical pulses by Garner, A.L., Nianyong Chen, Jing Yang, Kolb, J., Swanson, R.J., Loftin, K.C., Beebe, S.J., Joshi, R.P., Schoenbach, K.H.

“…Pulsed electric fields (PEFs) above a certain voltage threshold cause electroporation for microsecond pulses and intracellular effects for submicrosecond…”
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Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets by Prusa, Jerome, Jensen, Drake, Santiago-Collazo, Gustavo, Pope, Steven S, Garner, Ashley L, Miller, Justin J, Ruiz Manzano, Ana, Galburt, Eric A, Stallings, Christina L

“…The RNA polymerase (RNAP) binding protein A (RbpA) contributes to the formation of stable RNAP-promoter open complexes (RP ) and is essential for viability in…”
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Buckingham Pi Analysis of Railgun Multiphysics by Garner, Allen L., Lewis, Keith

“…Predicting railgun physics is complicated by the presence of multiple physical phenomena whose coupling is incompletely understood. Because computational…”
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AC gas breakdown scaling laws by Loveless, A. M., Garner, A. L.

“…Analytically predicting RF breakdown is vital for understanding plasma behavior. While theoretical and particle-in-cell (PIC) analyses have assessed RF…”
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Leukemic cell intracellular responses to nanosecond electric fields by Chen, Nianyong, Schoenbach, Karl H., Kolb, Juergen F., James Swanson, R., Garner, Allen L., Yang, Jing, Joshi, Ravindra P., Beebe, Stephen J.

“…Intense, nanosecond (ns) pulsed electric fields (PEFs) are known to affect the intracellular structures of cells. The probability of preferentially inducing…”
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Nanosecond electric pulses penetrate the nucleus and enhance speckle formation by Chen, Nianyong, Garner, Allen L., Chen, George, Jing, Yu, Deng, Yuping, Swanson, R. James, Kolb, Juergen F., Beebe, Stephen J., Joshi, Ravindra P., Schoenbach, Karl H.

“…Nanosecond electric pulses generate nanopores in the interior membranes of cells and modulate cellular functions. Here, we used confocal microscopy and flow…”
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To test or not to test? An updated evidence-based assessment of the value of screening and monitoring tests when using systemic biologic agents to treat psoriasis and psoriatic arthritis by Ahn, Christine S., MD, Dothard, Emily H., BA, Garner, Michael L., BA, Feldman, Steven R., MD, PhD, Huang, William W., MD, MPH

“…Background Safety profiles of systemic biologic agents for the treatment of psoriasis and psoriatic arthritis (PsA) encompass a wide spectrum of adverse…”
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Frequency dependence of electroporation of mammalian cells by pulsed high power radiofrequency and ultrawideband radiation by Jordan, D.W., Garner, A.L., Gilgenbach, R.M., Uhler, M.D., Gates, L., Lau, Y.Y.

“…Summary form only given. A series of experiments has been performed to determine the effectiveness of radiofrequency (RF) and ultrawideband electric fields for…”
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