Search Results - "Garman, Nadia"
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Gene therapy in rare diseases: the benefits and challenges of developing a patient-centric registry for Strimvelis in ADA-SCID
Published in Orphanet journal of rare diseases (06-04-2018)“…Strimvelis (autologous CD34+ cells transduced to express adenosine deaminase [ADA]) is the first ex vivo stem cell gene therapy approved by the European…”
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Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)
Published in European journal of nuclear medicine and molecular imaging (01-04-2020)“…Purpose The RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis through activation of transforming growth factor beta (TGFβ). This study…”
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Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants
Published in European journal of clinical pharmacology (01-06-2018)“…Purpose Inhaled drug delivery is an attractive route by which to deliver drugs to lungs of patients with idiopathic pulmonary fibrosis (IPF). GSK3008348 is a…”
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Series: Pragmatic trials and real world evidence: Paper 7. Safety, quality and monitoring
Published in Journal of clinical epidemiology (01-11-2017)“…Pragmatic trials offer the opportunity to obtain real-life data on the relative effectiveness and safety of a treatment before or after market authorization…”
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Collecting and Reporting Safety Data and Monitoring Trial Conduct In Pragmatic Trials
Published in Journal of clinical epidemiology (2017)“…Abstract Pragmatic trials offer the opportunity to obtain real-life data on the relative effectiveness and safety of a treatment before or after market…”
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A Microdose PET Study of the Safety, Immunogenicity, Biodistribution, and Radiation Dosimetry of 18F-FB-A20FMDV2 for Imaging the Integrin αvβ6
Published in Journal of nuclear medicine technology (01-06-2018)“…The αvβ6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid αvβ6-binding peptide, derived from the foot and mouth…”
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A Microdose PET Study of the Safety, Immunogenicity, Biodistribution, and Radiation Dosimetry of 18 F-FB-A20FMDV2 for Imaging the Integrin α v β 6
Published in Journal of nuclear medicine technology (01-06-2018)“…The α β integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid α β -binding peptide, derived from the foot and mouth…”
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