Search Results - "Garman, Elspeth"
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Radiation damage to biological macromolecules
Published in Current opinion in structural biology (01-10-2023)“…In this review, we describe recent research developments into radiation damage effects in macromolecular X-ray crystallography observed at synchrotrons and…”
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Developments in X-ray Crystallographic Structure Determination of Biological Macromolecules
Published in Science (American Association for the Advancement of Science) (07-03-2014)“…The three-dimensional structures of large biomolecules important in the function and mechanistic pathways of all living systems and viruses can be determined…”
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Raimond B. G. Ravelli (25 March 1968–30 June 2023)
Published in Acta crystallographica. Section D, Biological crystallography. (01-09-2023)“…Raimond B. G. Ravelli is remembered. Raimond B. G. Ravelli is remembered…”
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Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures
Published in Proceedings of the National Academy of Sciences - PNAS (25-02-2020)“…Radiation damage limits the accuracy of macromolecular structures in X-ray crystallography. Cryogenic (cryo-) cooling reduces the global radiation damage rate…”
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Quantifying and comparing radiation damage in the Protein Data Bank
Published in Nature communications (14-03-2022)“…Radiation damage remains one of the major bottlenecks to accurate structure solution in protein crystallography. It can induce structural and chemical changes…”
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RADDOSE-3D: time- and space-resolved modelling of dose in macromolecular crystallography
Published in Journal of applied crystallography (01-08-2013)“…RADDOSE‐3D allows the macroscopic modelling of an X‐ray diffraction experiment for the purpose of better predicting radiation‐damage progression. The…”
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7
Rosalind Franklin 1920–1958
Published in Acta crystallographica. Section D, Biological crystallography. (01-07-2020)“…An essay on Rosalind Franklin marking the 100th anniversary of her birth. An essay on Rosalind Franklin marking the 100th anniversary of her birth…”
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Radiation Damage in Macromolecular Crystallography
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Radiation damage inflicted on macromolecular crystals during X-ray diffraction experiments remains a limiting factor for structure solution, even when samples…”
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Radiation damage in macromolecular crystallography: what is it and why should we care?
Published in Acta crystallographica. Section D, Biological crystallography. (01-04-2010)“…Radiation damage inflicted during diffraction data collection in macromolecular crystallography has re‐emerged in the last decade as a major experimental and…”
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Radiation damage to biological samples: still a pertinent issue
Published in Journal of synchrotron radiation (01-09-2021)“…An understanding of radiation damage effects suffered by biological samples during structural analysis using both X‐rays and electrons is pivotal to obtain…”
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X‐ray radiation damage to biological samples: recent progress
Published in Journal of synchrotron radiation (01-07-2019)“…With the continuing development of beamlines for macromolecular crystallography (MX) over the last few years providing ever higher X‐ray flux densities, it has…”
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Identifying and avoiding radiation damage in macromolecular crystallography
Published in Acta crystallographica. Section D, Biological crystallography. (01-05-2024)“…Radiation damage remains one of the major impediments to accurate structure solution in macromolecular crystallography. The artefacts of radiation damage can…”
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X‐ray radiation damage to biological macromolecules: further insights
Published in Journal of synchrotron radiation (01-01-2017)“…Despite significant progress made over more than 15 years of research, structural biologists are still grappling with the issue of radiation damage suffered by…”
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Estimate your dose: RADDOSE‐3D
Published in Protein science (01-01-2018)“…We present the current status of RADDOSE‐3D, a software tool allowing the estimation of the dose absorbed in a macromolecular crystallography diffraction…”
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15
Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets
Published in Nature communications (23-03-2017)“…Crop yield loss due to flooding is a threat to food security. Submergence-induced hypoxia in plants results in stabilization of group VII ETHYLENE RESPONSE…”
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Welcoming two new Co‐editors
Published in Acta crystallographica. Section D, Biological crystallography. (01-11-2024)“…Two new Co‐editors are welcomed to Acta Cryst. D – Structural Biology. Two new Co‐editors are welcomed to Acta Cryst. D – Structural Biology…”
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Resolving the subtle details of human DNA alkyltransferase lesion search and repair mechanism by single-molecule studies
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2022)“…SignificanceWe directly visualize DNA translocation and lesion recognition by the O -alkylguanine DNA alkyltransferase (AGT). Our data show bidirectional…”
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Welcoming five new Co-editors
Published in Acta crystallographica. Section D, Biological crystallography. (01-03-2024)“…Five new Co-editors are appointed to the Editorial Board of Acta Cryst. D - Structural Biology…”
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RADDOSE‐XFEL: femtosecond time‐resolved dose estimates for macromolecular X‐ray free‐electron laser experiments
Published in Journal of applied crystallography (01-04-2020)“…For macromolecular structure determination at synchrotron sources, radiation damage remains a major limiting factor. Estimation of the absorbed dose (J kg−1)…”
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30 years of Acta D
Published in Acta crystallographica. Section D, Biological crystallography. (01-02-2023)“…Celebrating 30 years of Acta D and looking forward to the future of structural biology. Celebrating 30 years of Acta D and looking forward to the future of…”
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