Search Results - "Garlid, K D"

Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels : Possible mechanism of cardioprotection by GARLID, K. D, PAUCEK, P, YAROV-YAROVOY, V, MURRAY, H. N, DARBENZIO, R. B, D'ALONZO, A. J, LODGE, N. J, SMITH, M. A, GROVER, G. J

“…Previous studies showed a poor correlation between sarcolemmal K+ currents and cardioprotection for ATP-sensitive K+ channel (KATP) openers. Diazoxide is a…”
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Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondria by PAUCEK, P, MIRONOVA, G, MAHDI, F, BEAVIS, A. D, WOLDEGIORGIS, G, GARLID, K. D

“…The transport properties of mitochondria are such that net potassium flux across the inner membrane determines mitochondrial volume. It has been known that K+…”
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Mechanism of uncoupling protein action by Garlid, K D, Jaburek, M, Jezek, P

“…Two competing models of uncoupling protein (UCP) transport mechanism agree that fatty acids (FAs) are obligatory for uncoupling, but they disagree about which…”
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Opening mitochondrial K(ATP) in the heart--what happens, and what does not happen by Garlid, K D

“…There is considerable evidence that opening the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) is cardioprotective in ischemia-reperfusion. Two…”
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Cardioprotection by Ischemic Preconditioning Preserves Mitochondrial Function and Functional Coupling Between Adenine Nucleotide Translocase and Creatine Kinase by Laclau, M.N., Boudina, S., Thambo, J.B., Tariosse, L., Gouverneur, G., Bonoron-Adèle, S., Saks, V.A., Garlid, K.D., Dos Santos, P.

“…M. N. Laclau, S. Boudina, J. B. Thambo, L. Tariosse, G. Gouverneur, S. Bonoron-Adèle, V. A. Saks, K. D. Garlid and P. Dos Santos. Cardioprotection by Ischemic…”
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The Mitochondrial Potassium Cycle by Garlid, Keith D., Paucek, Petr

“…The mitochondrial K + cycle consists of influx and efflux pathways for K + and anions. Net movement of K + salts across the inner membrane causes changes of…”
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New substrates and competitive inhibitors of the Cl- translocating pathway of the uncoupling protein of brown adipose tissue mitochondria by Jezek, P, Garlid, K.D.

“…A large number of new substrates for anion uniport by the uncoupling protein of brown adipose tissue mitochondria have been found. These include…”
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On the regulation of K+ uniport in intact mitochondria by adenine nucleotides and nucleotide analogs by Beavis, A D, Lu, Y, Garlid, K D

“…Respiring mitochondria drive the electrophoretic uptake of K+ and other cations. In the presence of permeant acids this transport leads to mitochondrial…”
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Transport of anions and protons by the mitochondrial uncoupling protein and its regulation by nucleotides and fatty acids. A new look at old hypotheses by Jezek, P, Orosz, D E, Modriansky, M, Garlid, K D

“…The uncoupling protein generates heat by catalyzing electrophoretic proton transport across the inner membrane of brown adipose tissue mitochondria. It also…”
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Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter by TONINELLO, A, DALLA VIA, L, SILIPRANDI, D, GARLID, K. D

“…We present evidence that polyamine uptake into rat liver mitochondria is mediated by a specific polyamine uniporter. Polyamine transport is not mediated by the…”
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ATP-Sensitive Potassium Channels: A Review of their Cardioprotective Pharmacology by Grover, Gary J, Garlid, Keith D

“…G. J. Grover and K. A. Garlid. ATP-Sensitive Potassium Channels: A Review of their Cardioprotective Pharmacology. Journal of Molecular and Cellular Cardiology…”
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Reconstitution of the beef heart and rat liver mitochondrial K+/H+ (Na+/H+) antiporter. Quantitation of K+ transport with the novel fluorescent probe, PBFI by JEZEK, P, MAHDI, F, GARLID, K. D

“…New indicators for fluorescent measurement of Na+ and K+ ions should prove particularly useful for studies of reconstituted carriers of these ions. We show…”
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Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume by Beavis, A D, Brannan, R D, Garlid, K D

“…The amount of light scattered by a mitochondrial suspension depends on matrix volume (Tedeschi, H., and Harris, D.L. (1955) Arch. Biochem. Biophys. 58, 52-67),…”
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Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria by Kowaltowski, A J, Seetharaman, S, Paucek, P, Garlid, K D

“…There is an emerging consensus that pharmacological opening of the mitochondrial ATP-sensitive K(+) (K(ATP)) channel protects the heart against…”
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Identification and Properties of a Novel Intracellular (Mitochondrial) ATP-sensitive Potassium Channel in Brain by Bajgar, Robert, Seetharaman, Subramaniam, Kowaltowski, Alicia J., Garlid, Keith D., Paucek, Petr

“…Protection of heart against ischemia-reperfusion injury by ischemic preconditioning and KATP channel openers is known to involve the mitochondrial…”
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On the mechanism of spermine transport in liver mitochondria by Toninello, A, Miotto, G, Siliprandi, D, Siliprandi, N, Garlid, K D

“…Spermine penetrates the mitochondrial matrix at significant rates which increase sharply and non-ohmically with membrane potential. In this respect, spermine…”
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AA1, a newly synthesized monovalent lipophilic cation, expresses potent in vivo antitumor activity by XIAOCHENG SUN, WONG, J. R, KAILI SONG, HU, J, GARLID, K. D, LAN BO CHEN

“…Certain lipophilic cations have been reported to display anticarcinoma activities because of their selective uptake and retention by mitochondria of cancer…”
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The mitochondrial inner membrane anion channel. Regulation by divalent cations and protons by Beavis, A D, Garlid, K D

“…It is now well established that incubation of mitochondria at pH 8 or higher opens up an electrophoretic anion transport pathway in the inner membrane. It is…”
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On the mechanism by which bupivacaine conducts protons across the membranes of mitochondria and liposomes by Sun, X, Garlid, K D

“…Bupivacaine and etidocaine possess the remarkable property of stimulating mitochondrial respiration to levels comparable with those observed with classical…”
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Reconstitution of the uncoupling protein of brown adipose tissue mitochondria. Demonstration of GDP-sensitive halide anion uniport by Jezek, P, Orosz, D.E., Garlid, K.D.

“…The fluorescent anion indicator 6-methoxy-N-(3-sulfopropyl)quinolinium was trapped in proteoliposomes reconstituted with purified 32-kDa uncoupling protein and…”
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