Search Results - "Gariepy, C E"
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Postnatal intestinal engraftment of prospectively selected enteric neural crest stem cells in a rat model of Hirschsprung disease
Published in Neurogastroenterology and motility (01-04-2011)“…Background Identification of neuronal progenitor/stem cells in the postnatal gut suggests the development of transplantation approaches to enteric nervous…”
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Intestinal motility disorders and development of the enteric nervous system
Published in Pediatric research (01-05-2001)Get full text
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Endothelin b receptor deficient transgenic rescue rats: a rescue phenomenon in the brain
Published in Neuroscience (2004)“…Homozygous endothelin B receptor deficiency leads to congenital aganglionosis of the gut in rats and mice, equivalent to human Hirschsprung disease. Homozygous…”
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Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease
Published in The Journal of clinical investigation (15-09-1998)“…The spotting lethal rat, a naturally occurring rodent model of Hirschsprung disease, carries a deletion in the endothelin-B receptor (EDNRB) gene that…”
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Null Mutation of Endothelin Receptor Type B Gene in Spotting Lethal Rats Causes Aganglionic Megacolon and White Coat Color
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-1996)“…Mutations in the gene encoding the endothelin receptor type B (EDNRB) produce congenital aganglionic megacolon and pigment abnormalities in mice and humans…”
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Exaggerated vascular and renal pathology in endothelin-b receptor-deficient rats with deoxycorticosterone acetate-salt hypertension
Published in Circulation (New York, N.Y.) (28-11-2000)“…Endothelin (ET)-1 plays an important role in the pathogenesis of deoxycorticosterone acetate (DOCA)-salt-induced hypertension. We evaluated the pathological…”
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Salt-sensitive hypertension in endothelin-B receptor-deficient rats
Published in The Journal of clinical investigation (01-04-2000)“…The role of the endothelin-B receptor (ET(B)) in vascular homeostasis is controversial because the receptor has both pressor and depressor effects in vivo…”
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Endothelin B receptor deficiency potentiates ET-1 and hypoxic pulmonary vasoconstriction
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2001)“…Endothelin (ET)-1 contributes to the regulation of pulmonary vascular tone by stimulation of the ET(A) and ET(B) receptors. Although activation of the ET(A)…”
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Gender Differences in ET and NOS Systems in ETB Receptor-Deficient Rats: Effect of a High Salt Diet
Published in Hypertension (Dallas, Tex. 1979) (01-03-2003)“…ABSTRACT—The purpose of this study was to determine if rats lacking the ETB receptor have altered renal endothelin (ET) production and NO synthase (NOS)…”
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Renal tubular effects of endothelin-B receptor signaling: its role in cardiovascular homeostasis and extracellular volume regulation
Published in Current opinion in nephrology and hypertension (01-07-2000)“…The role of the endothelin-B receptor in vascular homeostasis is controversial because the receptor has both pressor and depressor effects in vivo. One…”
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Enhanced blood pressure sensitivity to DOCA‐salt treatment in endothelin ETB receptor‐deficient rats
Published in British journal of pharmacology (01-03-2000)“…The role of endothelin ETB receptor‐mediated action in the development and maintenance of deoxycorticosterone acetate (DOCA)‐salt‐induced hypertension was…”
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Developmental Disorders of the Enteric Nervous System: Genetic and Molecular Bases
Published in Journal of pediatric gastroenterology and nutrition (01-07-2004)Get full text
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SPLINT: a cubic spline interpolation program for the analysis of fragment sizes in one-dimensional electrophoresis gels
Published in Nucleic acids research (10-01-1986)“…SPLINT (SPLine INTerpolation) is a BASIC microcomputer program that uses electrophoretic data on the migration distances of DNA fragments of known size to…”
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Temporally Distinct Requirements for Endothelin Receptor B in the Generation and Migration of Gut Neural Crest Stem Cells
Published in Neuron (Cambridge, Mass.) (04-12-2003)“…Loss of Endothelin-3/Endothelin receptor B (EDNRB) signaling leads to aganglionosis of the distal gut (Hirschsprung's disease), but it is unclear whether it is…”
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Enhanced blood pressure sensitivity to DOCA-salt treatment in endothelin ET(B) receptor-deficient rats
Published in British journal of pharmacology (01-03-2000)“…The role of endothelin ET(B) receptor-mediated action in the development and maintenance of deoxycorticosterone acetate (DOCA)-salt-induced hypertension was…”
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Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts
Published in Circulation (New York, N.Y.) (25-01-2005)“…Endothelin (ET)-1 and norepinephrine (NE) are involved in myocardial ischemia/reperfusion injury. We investigated the role of ET-1 in…”
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Reduced expression of endothelin B receptors and mechanical hyperalgesia in experimental chronic diabetes
Published in Experimental neurology (01-10-2006)“…Diabetic neuropathy is one of the major complications of diabetes mellitus. Small nerve fibers degenerate early in the disease, leading to symptoms ranging…”
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Genetic basis of Hirschsprung disease: implications in clinical practice
Published in Molecular Genetics and Metabolism (01-09-2003)Get full text
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