Search Results - "Garibotto, Valentina"
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Projection Space Implementation of Deep Learning-Guided Low-Dose Brain PET Imaging Improves Performance over Implementation in Image Space
Published in Journal of Nuclear Medicine (01-09-2020)“…Our purpose was to assess the performance of full-dose (FD) PET image synthesis in both image and sinogram space from low-dose (LD) PET images and sinograms…”
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Deep learning‐guided joint attenuation and scatter correction in multitracer neuroimaging studies
Published in Human brain mapping (01-09-2020)“…PET attenuation correction (AC) on systems lacking CT/transmission scanning, such as dedicated brain PET scanners and hybrid PET/MRI, is challenging. Direct AC…”
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EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0
Published in European journal of nuclear medicine and molecular imaging (01-07-2020)“…Purpose This joint practice guideline or procedure standard was developed collaboratively by the European Association of Nuclear Medicine (EANM) and the…”
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Gender differences in healthy aging and Alzheimer's Dementia: A 18F‐FDG‐PET study of brain and cognitive reserve
Published in Human brain mapping (01-08-2017)“…Cognitive reserve (CR) and brain reserve (BR) are protective factors against age‐associated cognitive decline and neurodegenerative disorders. Very limited…”
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EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3
Published in European journal of nuclear medicine and molecular imaging (01-01-2022)“…The present procedural guidelines summarize the current views of the EANM Neuro-Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear…”
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Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework
Published in European journal of nuclear medicine and molecular imaging (2021)“…Purpose In 2017, the Geneva Alzheimer’s disease (AD) strategic biomarker roadmap initiative proposed a framework of the systematic validation AD biomarkers to…”
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[18F]FDOPA positron emission tomography for cardiac innervation imaging: a new way or a dead-end street?
Published in Clinical autonomic research (01-12-2022)Get full text
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Highlights of the 32th Annual Congress of the EANM, Barcelona 2019: the nucleolympic games of nuclear medicine—a global competition for excellence
Published in European journal of nuclear medicine and molecular imaging (01-07-2020)“…The 32th Annual Congress of the European Association of Nuclear Medicine (EANM) returned to Barcelona, Spain, from the 12th to the 16th of October 2019, under…”
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Distinctive clinical and imaging trajectories in SWEDD and Parkinson’s disease patients
Published in NeuroImage clinical (01-01-2024)“…•PD showed lower 123I-FP-CIT-binding than SWEDD at the same symptoms’ severity.•PD and SWEDD showed altered molecular connectivity but with different…”
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Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework
Published in Neurobiology of aging (01-04-2017)“…Abstract The use of Alzheimer's disease (AD) biomarkers is supported in diagnostic criteria, but their maturity for clinical routine is still debated. Here, we…”
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In Vivo TSPO Signal and Neuroinflammation in Alzheimer's Disease
Published in Cells (Basel, Switzerland) (21-08-2020)“…In the last decade, positron emission tomography (PET) and single-photon emission computed tomography (SPECT) in in vivo imaging has attempted to demonstrate…”
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A 3D deep learning model to predict the diagnosis of dementia with Lewy bodies, Alzheimer’s disease, and mild cognitive impairment using brain 18F-FDG PET
Published in European journal of nuclear medicine and molecular imaging (01-01-2022)“…Purpose The purpose of this study is to develop and validate a 3D deep learning model that predicts the final clinical diagnosis of Alzheimer’s disease (AD),…”
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Diagnostic value of amyloid-PET and tau-PET: a head-to-head comparison
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Purpose Assess the individual and combined diagnostic value of amyloid-PET and tau-PET in a memory clinic population. Methods Clinical reports of 136 patients…”
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Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework
Published in Neurobiology of aging (01-04-2017)“…Abstract The use of biomarkers has been proposed for diagnosing Alzheimer's disease in recent criteria, but some biomarkers have not been sufficiently…”
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The role of molecular imaging in assessing degenerative parkinsonism - an updated review
Published in Swiss medical weekly (26-04-2018)“…Diagnosing degenerative forms of parkinsonism still relies on a thorough clinical assessment, which in Parkinson's disease involves the presence of an…”
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Preserved Extrastriatal 123I-FP-CIT Binding in Scans Without Evidence of Dopaminergic Deficit (SWEDD)
Published in Molecular imaging and biology (01-12-2020)“…Purpose Scans without evidence of dopaminergic deficit (SWEDD) have been initially described in a minority of subjects with suspected Parkinson’s disease (PD)…”
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Feeling of presence in dementia with Lewy bodies is related to reduced left frontoparietal metabolism
Published in Brain imaging and behavior (01-08-2020)“…Feeling of presence (FOP) refers to the vivid sensation of a person’s presence near oneself and is common in Dementia with Lewy Bodies (DLB). Based on previous…”
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Outcomes of clinical utility in amyloid-PET studies: state of art and future perspectives
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Purpose To review how outcomes of clinical utility are operationalized in current amyloid-PET validation studies, to prepare for formal assessment of clinical…”
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