Search Results - "Gargett, C E"

Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium by Schwab, K.E., Gargett, C.E.

“…BACKGROUND Human endometrium has immense regenerative capacity, growing ~5 mm in 7 days every month. We have previously identified a small population of…”
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Uterine stem cells: What is the evidence? by Gargett, C E

“…The mucosal lining (endometrium) of the human uterus undergoes cyclical processes of regeneration, differentiation and shedding as part of the menstrual cycle…”
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Identification of surface markers for prospective isolation of human endometrial stromal colony-forming cells by Schwab, K.E., Hutchinson, P., Gargett, C.E.

“…BACKGROUND Human endometrium is a highly regenerative tissue. We hypothesized that the source of endometrial stromal and vascular regeneration is a resident…”
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Platelet lysate can support the development of a 3D-engineered skin for clinical application by Banakh, I., Rahman, Md. M., Arellano, C. L., Marks, D. C., Mukherjee, S., Gargett, C. E., Cleland, H., Akbarzadeh, S.

“…Safety concerns associated with foetal bovine serum (FBS) have restricted its translation into clinics. We hypothesised that platelet lysate (PL) can be…”
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Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice by Darzi, S., Deane, J. A., Nold, C. A., Edwards, S. E., Gough, D. J., Mukherjee, S., Gurung, S., Tan, K. S., Vashi, A. V., Werkmeister, J. A., Gargett, C. E.

“…The immunomodulatory properties of human endometrial mesenchymal stem cells (eMSC) have not been well characterised. Initial studies showed that eMSC modulated…”
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The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis by Cousins, F L, Farley, J K, Kerrigan, R, Mukherjee, S, Darzi, S, Gargett, C E, Deane, J A

“…Endometriosis is a common and painful condition characterised by the formation of endometrial lesions within the peritoneal cavity. Previous studies have…”
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Reply: An update on endometrial stem cells and progenitors by Deepa Bhartiya by Gargett, C E, Deane, J A, Schwab, K E

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Temporal changes in the biomechanical properties of endometrial mesenchymal stem cell seeded scaffolds in a rat model by Edwards, S.L., Ulrich, D., White, J.F., Su, K., Rosamilia, A., Ramshaw, J.A.M., Gargett, C.E., Werkmeister, J.A.

“…[Display omitted] Use of synthetic clinical meshes in pelvic organ prolapse (POP) repair can lead to poor mechanical compliance in vivo, as a result of a…”
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Human endometrial angiogenesis by Gargett, CE, Rogers, PA

“…Angiogenesis is the development of new microvessels from existing vessels, a process that involves microvascular endothelial cells. Physiological angiogenesis…”
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Menstrual fluid endometrial stem/progenitor cell and supernatant protein content: cyclical variation and indicative range by Wyatt, K A, Filby, C E, Davies-Tuck, M L, Suke, S G, Evans, J, Gargett, C E

“…Does natural variation exist in the endometrial stem/progenitor cell and protein composition of menstrual fluid across menstrual cycles in women? Limited…”
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Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis by Hapangama, D K, Drury, J, Da Silva, L, Al-Lamee, H, Earp, A, Valentijn, A J, Edirisinghe, D P, Murray, P A, Fazleabas, A T, Gargett, C E

“…Abstract STUDY QUESTION Is endometriosis associated with abnormally located endometrial basalis-like (SSEA1+/SOX9+) cells in the secretory phase functionalis…”
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SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis by Valentijn, A.J., Palial, K., Al-lamee, H., Tempest, N., Drury, J., Von Zglinicki, T., Saretzki, G., Murray, P., Gargett, C.E., Hapangama, D.K.

“…STUDY QUESTION Can the basal epithelial compartment of the human endometrium be defined by specific markers? SUMMARY ANSWER Human endometrial epithelial cells…”
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Mesenchymal stem/stromal cells in post-menopausal endometrium by Ulrich, D., Tan, K.S., Deane, J., Schwab, K., Cheong, A., Rosamilia, A., Gargett, C.E.

“…STUDY QUESTION Does post-menopausal endometrium contain mesenchymal stem/stromal cells (MSC) that have adult stem cell properties and can be prospectively…”
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Composite mesh design for delivery of autologous mesenchymal stem cells influences mesh integration, exposure and biocompatibility in an ovine model of pelvic organ prolapse by Emmerson, S., Mukherjee, S., Melendez-Munoz, J., Cousins, F., Edwards, S.L., Karjalainen, P., Ng, M., Tan, K.S., Darzi, S., Bhakoo, K., Rosamilia, A., Werkmeister, J.A., Gargett, C.E.

“…The widespread use of synthetic transvaginal polypropylene mesh for treating Pelvic Organ Prolapse (POP) has been curtailed due to serious adverse effects…”
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Lack of correlation between vascular endothelial growth factor production and endothelial cell proliferation in the human endometrium by Gargett, C.E., Lederman, F.L., Lau, T.M., Taylor, N.H., Rogers, P.A.W.

“…The role of vascular endothelial growth factor (VEGF) in endometrial angiogenesis was examined by measuring its production in human endometrial tissues from…”
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Bone marrow-derived endometrial cells: transdifferentiation or misidentification? by Deane, J A, Ong, Y, Cousins, F L, Gargett, C E

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Stem Cells from Fetal Membranes – A Workshop Report by Hemberger, M, Yang, W, Natale, D, Brown, T.L, Dunk, C, Gargett, C.E, Tanaka, S

“…Abstract Stem cells that can be derived from fetal membranes represent an exciting field of research that bears tremendous potential for developmental biology…”
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The isoquinoline derivative KN‐62 a potent antagonist of the P2Z‐receptor of human lymphocytes by Gargett, Caroline E., Wiley, James S.

“…Extracellular adenosine 5′‐triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of a cation‐selective ion channel,…”
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Potential role of endometrial stem/progenitor cells in the pathogenesis of early-onset endometriosis by Gargett, C E, Schwab, K E, Brosens, J J, Puttemans, P, Benagiano, G, Brosens, I

“…The pathogenesis of early-onset endometriosis has recently been revisited, sparked by the discovery of endometrial stem/progenitor cells and their possible…”
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Focal vascular endothelial growth factor correlates with angiogenesis in human endometrium. Role of intravascular neutrophils by Gargett, Caroline E., Lederman, Fiona, Heryanto, Bambang, Gambino, Lara S., Rogers, Peter A.W.

“…Vascular endothelial growth factor (VEGF) is expressed in human endometrium, but the cellular source of VEGF for endometrial angiogenesis has not been…”
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