Search Results - "Gargani, Sofia"
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Endonucleosis mediates internalization of cytoplasm into the nucleus
Published in Nature communications (11-07-2024)“…Setd8 regulates transcription elongation, mitotic DNA condensation, DNA damage response and replication licensing. Here we show that, in mitogen-stimulated…”
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Genetic Identity of Neural Crest Cell Differentiation in Tissue and Organ Development
Published in Frontiers in bioscience (Landmark. Print) (22-07-2024)“…The neural crest (NC), also known as the "fourth germ layer", is an embryonic structure with important contributions to multiple tissue and organ systems…”
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Inactivation of AUF1 in Myeloid Cells Protects From Allergic Airway and Tumor Infiltration and Impairs the Adenosine-Induced Polarization of Pro-Angiogenic Macrophages
Published in Frontiers in immunology (11-02-2022)“…The four isoforms of the RNA-binding protein hnRNPD/AUF1 have been proposed to limit the use of inflammatory mRNAs in innate immune cells. Mice engineered to…”
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Comment on: Saisho et al. β-cell mass and turnover in humans: effects of obesity and aging. Diabetes Care 2013;36:111-117
Published in Diabetes care (01-07-2013)Get full text
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Effectiveness of protocol for the isolation of Wharton's Jelly stem cells in large-scale applications
Published in In vitro cellular & developmental biology. Animal (01-12-2009)“…The Wharton's Jelly (WJ) of the umbilical cord (UC) is an excellent source of mesenchymal stem cells (MSCs) with a range of potential therapeutic applications…”
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Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes
Published in PloS one (27-08-2013)“…Pax4 and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene homolog A) are two transcription factors crucial for normal functions of islet beta cells in the…”
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MicroRNA-7a regulates pancreatic β cell function
Published in The Journal of clinical investigation (01-06-2014)“…Dysfunctional microRNA (miRNA) networks contribute to inappropriate responses following pathological stress and are the underlying cause of several disease…”
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PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression
Published in The Journal of clinical investigation (01-06-2020)“…As there is growing evidence for the tumor microenvironment's role in tumorigenesis, we investigated the role of fibroblast-expressed kinases in…”
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2056-P: In Vivo Human Islet Compensation and Dysfunction to Diet-Induced Obesity: A Phase 0 Preclinical Model
Published in Diabetes (New York, N.Y.) (01-06-2020)“…A translational discrepancy exists between animal models used for diabetes research and diabetes in man, thus human relevant models must become a priority. We…”
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The RNA binding protein human antigen R is a gatekeeper of liver homeostasis
Published in Hepatology (Baltimore, Md.) (01-04-2022)“…Background and Aims NAFLD is initiated by steatosis and can progress through fibrosis and cirrhosis to HCC. The RNA binding protein human antigen R (HuR)…”
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PIK3C[delta] expression by fibroblasts promotes triple-negative breast cancer progression
Published in The Journal of clinical investigation (01-06-2020)“…As there is growing evidence for the tumor microenvironment's role in tumorigenesis, we investigated the role of fibroblast-expressed kinases in…”
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L’adaptation de la masse et de la fonction des îlots humains persiste au delà de 55 ans
Published in Diabetes & metabolism (01-03-2017)Get full text
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CA-186 - L’adaptation de la masse et de la fonction des îlots humains persiste au delà de 55 ans
Published in Diabetes & metabolism (01-03-2017)Get full text
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MicroRNA-7a regulates pancreatic [Beta] cell function
Published in The Journal of clinical investigation (01-06-2014)“…Dysfunctional microRNA (miRNA) networks contribute to inappropriate responses following pathological stress and are the underlying cause of several disease…”
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Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes: e72194
Published in PloS one (01-08-2013)“…Pax4 and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene homolog A) are two transcription factors crucial for normal functions of islet beta cells in the…”
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A Rapid and Accurate Method for the Stem Cell Viability Evaluation: The Case of the Thawed Umbilical Cord Blood
Published in Laboratory medicine (01-09-2009)“…The umbilical cord blood is a major source of hematopoletic progenitor cells. The cells can be cryopreserved for possible future use. Here, Katsares et al…”
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