Search Results - "Garg, Prabha"

Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV‑2 Main Protease by Gahlawat, Anuj, Kumar, Navneet, Kumar, Rajender, Sandhu, Hardeep, Singh, Inder Pal, Singh, Saranjit, Sjöstedt, Anders, Garg, Prabha

“…The COVID-19 disease is caused by a new strain of the coronavirus family (SARS-CoV-2), and it has affected at present millions of people all over the world…”
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Machine learning-based modeling to predict inhibitors of acetylcholinesterase by Sandhu, Hardeep, Kumar, Rajaram Naresh, Garg, Prabha

“…Acetylcholinesterase enzyme is responsible for the degradation of acetylcholine and is an important drug target for the treatment of Alzheimer’s disease. When…”
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Machine learning-enabled predictive modeling to precisely identify the antimicrobial peptides by Wani, Mushtaq Ahmad, Garg, Prabha, Roy, Kuldeep K.

“…The ubiquitous antimicrobial peptides (AMPs), with a broad range of antimicrobial activities, represent a great promise for combating the multi-drug resistant…”
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CRAFT: a web-integrated cavity prediction tool based on flow transfer algorithm by Gahlawat, Anuj, Singh, Anjali, Sandhu, Hardeep, Garg, Prabha

“…Numerous computational methods, including evolutionary-based, energy-based, and geometrical-based methods, are utilized to identify cavities inside proteins…”
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Design, Synthesis, and biological evaluation of pyrazolo-benzothiazole derivatives as a potential therapeutic agent for the treatment of Alzheimer’s disease by Kumar, Harish, Goyal, Anju, Kumar, Navneet, Garg, Prabha

“…Alzheimer’s disease (AD) is a neurodegenerative age-related brain disease which diminishes learning and memory. Two main cholinesterases (ChEs), first…”
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Ultrasonic disruption of Pseudomonas putida for the release of arginine deiminase: Kinetics and predictive models by Patil, Mahesh D., Dev, Manoj J., Tangadpalliwar, Sujit, Patel, Gopal, Garg, Prabha, Chisti, Yusuf, Banerjee, Uttam Chand

“…•Ultrasound-mediated ADI release from P. putida using machine learning techniques.•Satisfactory prediction of the responses implied the proficient capabilities…”
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Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches by Belekar, Vilas, Lingineni, Karthik, Garg, Prabha

“…The breast cancer resistant protein (BCRP) is an important transporter and its inhibitors play an important role in cancer treatment by improving the oral…”
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Virtual autism among children: A leading hazard of gadget exposure and preventive measures by Garg, Ram K., Garg, Prabha, Sharma, Poonam, Kumar, Yogesh, Niwas, Ram, Singh, Jitendra, Singh, Sapna

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Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin by Malhotra, Himanshu, Patidar, Anil, Boradia, Vishant M, Kumar, Rajender, Nimbalkar, Rakesh D, Kumar, Ajay, Gani, Zahid, Kaur, Rajbeer, Garg, Prabha, Raje, Manoj, Raje, Chaaya I

“…Iron is crucial for the survival of living cells, particularly the human pathogen which uses multiple strategies to acquire and store iron. synthesizes high…”
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Synthesis and Antileishmanial activity of Piperoyl-Amino Acid Conjugates by Singh, Inder Pal, Jain, Shreyans Kumar, Kaur, Amandeep, Singh, Sukhvinder, Kumar, Rajender, Garg, Prabha, Sharma, Shyam Sundar, Arora, Sunil Kumar

“…Based on reported antileishmanial activity of naturally occurring alkaloid piperine and amino acid esters, their conjugates were synthesized by the hydrolysis…”
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Classification of Human Pregnane X Receptor (hPXR) Activators and Non-Activators by Machine Learning Techniques: A Multifaceted Approach by Rathod, Vijay, Belekar, Vilas, Garg, Prabha, Sangamwar, Abhay T

“…The Human Pregnane X Receptor (hPXR) is a regulator of drug metabolising enzymes (DME) and efflux transporters (ET). The prediction of hPXR activators and…”
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Disruption of Pseudomonas putida by high pressure homogenization: a comparison of the predictive capacity of three process models for the efficient release of arginine deiminase by Patil, Mahesh D., Patel, Gopal, Surywanshi, Balaji, Shaikh, Naeem, Garg, Prabha, Chisti, Yusuf, Banerjee, Uttam Chand

“…Disruption of Pseudomonas putida KT2440 by high-pressure homogenization in a French press is discussed for the release of arginine deiminase (ADI). The enzyme…”
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QSAR study of curcumine derivatives as HIV-1 integrase inhibitors by Gupta, Pawan, Sharma, Anju, Garg, Prabha, Roy, Nilanjan

“…A QSAR study was performed on curcumine derivatives as HIV-1 integrase inhibitors using multiple linear regression. The statistically significant model was…”
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Prediction of drug-resistance in HIV-1 subtype C based on protease sequences from ART naive and first-line treatment failures in North India using genotypic and docking analysis by Toor, Jaideep S., Sharma, Aman, Kumar, Rajender, Gupta, Pawan, Garg, Prabha, Arora, Sunil K.

“…► DR genotyping of HIV isolates from therapy-naive and treatment-failures conducted. ► Docking of various PI drugs attempted on computational model of HIV…”
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Machine Learning Enables Accurate Prediction of Quinone Formation during Drug Metabolism by Sandhu, Hardeep, Garg, Prabha

“…Metabolism helps in the elimination of drugs from the human body by making them more hydrophilic. Sometimes, drugs can be bioactivated to highly reactive…”
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Probing the Molecular Basis of Cofactor Affinity and Conformational Dynamics of Mycobacterium tuberculosis Elongation Factor Tu: An Integrated Approach Employing Steered Molecular Dynamics and Umbrella Sampling Simulations by Kumar, Navneet, Garg, Prabha

“…The emergence of multidrug-resistant and extensively drug-resistant tuberculosis strains is the reason that the infectious tuberculosis pathogen is still the…”
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Deep learning-based prediction model for diagnosing gastrointestinal diseases using endoscopy images by Sharma, Anju, Kumar, Rajnish, Garg, Prabha

“…[Display omitted] •A large number of people worldwide suffer from gastrointestinal (GI) diseases for a variety of reasons.•Image-based classification models…”
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AndroPred: an artificial intelligence-based model for predicting androgen receptor inhibitors by Gagare, Rohit, Sharma, Anju, Garg, Prabha

“…Androgen receptor (AR), a steroid receptor, plays a pivotal role in the pathogenesis of prostate cancer (PCa). AR controls the transcription of genes that help…”
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Artificial intelligence in intestinal polyp and colorectal cancer prediction by Sharma, Anju, Kumar, Rajnish, Yadav, Garima, Garg, Prabha

“…Artificial intelligence (AI) algorithms and their application to disease detection and decision support for healthcare professions have greatly evolved in the…”
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Unlocking translational machinery for antitubercular drug development by Kumar, Navneet, Wani, Mushtaq Ahmad, Raje, Chaaya Iyengar, Garg, Prabha

“…Targeting translational factor proteins (TFPs) presents significant promise for the development of innovative antitubercular drugs. Previous insights from…”
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