Search Results - "Garfield, Victoria"

The Association Between Body Mass Index (BMI) and Sleep Duration: Where Are We after nearly Two Decades of Epidemiological Research? by Garfield, Victoria

“…Over the past twenty years we have seen a vast number of epidemiological studies emerge on the topic of obesity and sleep duration, with a focus on body mass…”
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The relationship between sleep duration, cognition and dementia: a Mendelian randomization study by Henry, Albert, Katsoulis, Michail, Masi, Stefano, Fatemifar, Ghazaleh, Denaxas, Spiros, Acosta, Dionisio, Garfield, Victoria, Dale, Caroline E

“…Abstract Background Short and long sleep duration have been linked with poorer cognitive outcomes, but it remains unclear whether these associations are…”
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A brief comparison of polygenic risk scores and Mendelian randomisation by Garfield, Victoria, Anderson, Emma L

“…Mendelian randomisation and polygenic risk score analysis have become increasingly popular in the last decade due to the advent of large-scale genome-wide…”
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A cross-sectional observational study for ethno-geographical disparities in sleep quality, brain morphometry and cognition (a SOLACE study) in Indians residing in India, and South Asians and Europeans residing in the UK - a study protocol by Soni, Rishabh, Dale, Caroline, Garfield, Victoria, Akhtar, Nasreen

“…As individuals age, their sleep patterns change, and sleep disturbances can increase the risk of dementia. Poor sleep quality can be a risk factor for mild…”
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The relationship between sleep quality and all-cause, CVD and cancer mortality: the Southall and Brent REvisited study (SABRE) by Garfield, Victoria, Joshi, Roshni, Garcia-Hernandez, Jorge, Tillin, Therese, Chaturvedi, Nish

“…Both long and short sleep duration increase risk of mortality. Most previous studies have been performed in Europeans and have focused on sleep duration. Thus,…”
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HbA1c and brain health across the entire glycaemic spectrum by Garfield, Victoria, Farmaki, Aliki‐Eleni, Eastwood, Sophie V., Mathur, Rohini, Rentsch, Christopher T., Bhaskaran, Krishnan, Smeeth, Liam, Chaturvedi, Nish

“…Aim To understand the relationship between HbA1c and brain health across the entire glycaemic spectrum. Materials and Methods We used data from the UK Biobank…”
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Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study by Norris, Tom, Sanderson, Eleanor, Cooper, Rachel, Garfield, Victoria, Pereira, Snehal M. Pinto

“…The relationship between adiposity and grip strength (GS) is complex. We investigated whether one pathway through which adiposity affects GS was via chronic…”
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Adiposity and grip strength: a Mendelian randomisation study in UK Biobank by Pinto Pereira, Snehal M, Garfield, Victoria, Farmaki, Aliki-Eleni, Tomlinson, David J, Norris, Thomas, Fatemifar, Ghazaleh, Denaxas, Spiros, Finan, Chris, Cooper, Rachel

“…Muscle weakness, which increases in prevalence with age, is a major public health concern. Grip strength is commonly used to identify weakness and an improved…”
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The relationship between physical activity, sleep duration and depressive symptoms in older adults: The English Longitudinal Study of Ageing (ELSA) by Garfield, Victoria, Llewellyn, Clare H, Kumari, Meena

“…Abstract Research to date suggests that physical activity (PA) is associated with distinct aspects of sleep, but studies have predominantly focused on sleep…”
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Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records by Muzambi, Rutendo, Bhaskaran, Krishnan, Rentsch, Christopher T., Smeeth, Liam, Brayne, Carol, Garfield, Victoria, Williams, Dylan M., Chaturvedi, Nish, Warren-Gash, Charlotte

“…While there is growing evidence of associations between infections and dementia risk, associations with cognitive impairment and potential structural…”
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Sleep duration: A review of genome-wide association studies (GWAS) in adults from 2007 to 2020 by Garfield, Victoria

“…A modest body of research exists in the area of human sleep genetics, which suggests that specific sleep phenotypes are, like many other complex traits,…”
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Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank by Rentsch, Christopher T, Farmer, Ruth E, Eastwood, Sophie V, Mathur, Rohini, Garfield, Victoria, Farmaki, Aliki-Eleni, Bhaskaran, Krishnan, Chaturvedi, Nish, Smeeth, Liam

“…IntroductionDiabetes is observed to increase cancer risk, leading to hypothesized direct effects of either hyperglycemia or medication. We investigated…”
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Understanding the inter‐relationships of type 2 diabetes and hypertension with brain and cognitive health: A UK Biobank study by Newby, Danielle, Garfield, Victoria

“…Aim To understand the impact of diabetes and co‐morbid hypertension on cognitive and brain health. Materials and Methods We used data from the UK Biobank…”
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Associations between residential daytime indoor temperature and self-reported sleep disturbances in UK adults: A cross-sectional study by Deng, Ruiwen, Victoria, Garfield, Ucci, Marcella

“…In the past few decades, research on the association between indoor temperature and sleep has primarily used laboratory rather than field data collected in…”
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Corrigendum to <'Associations between residential daytime indoor temperature and self-reported sleep disturbances in UK adults: A cross-sectional study'> Environ. Res. 257 (2024) 119281 by Deng, Ruiwen, Garfield, Victoria, Ucci, Marcella

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Corrigendum to <‘Associations between residential daytime indoor temperature and self-reported sleep disturbances in UK adults: A cross-sectional study’> [Environ. Res. 257 (2024) 119281] by Deng, Ruiwen, Garfield, Victoria, Ucci, Marcella

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A Guide for Selection of Genetic Instruments in Mendelian randomisation (MR) studies of Type-2 diabetes and HbA1c: towards an integrated approach by Garfield, Victoria, Salzmann, Antoine, Burgess, Stephen, Chaturvedi, Nish

“…This study examines the instrument selection strategies currently employed throughout the type-2 diabetes and HbA 1c MR literature. We then argue for a more…”
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A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach by Garfield, Victoria, Salzmann, Antoine, Burgess, Stephen, Chaturvedi, Nish

“…In this study we examine the instrument selection strategies currently used throughout the type 2 diabetes and HbA1c Mendelian randomization (MR) literature…”
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Abstract 14266: Is the Association Between Coronary Artery Disease and Adverse Brain Health Causal? A Combined Observational and Mendelian Randomisation Study by Topriceanu, Constantin-Cristian, Hussain, Resham, Dale, Caroline, Park, Chloe M, Chaturvedi, Nishi, FATEMIFAR, Ghazaleh, Garfield, Victoria

“…Abstract only Introduction: Although coronary artery disease (CAD) is associated with worse brain health in observational studies, whether this is causal…”
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Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations by Topriceanu, Constantin-Cristian, Chaturvedi, Nish, Mathur, Rohini, Garfield, Victoria

“…Polygenic scores (PGSs) provide an individual level estimate of genetic risk for any given disease. Since most PGSs have been derived from genome wide…”
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