Search Results - "Gareau, Alison J."

Donor specific HLA antibody in hematopoietic stem cell transplantation: Implications for donor selection by Krummey, Scott M, Gareau, Alison J

“…Advances in hematopoietic stem cell transplant (HSCT) have led to changes in the approach to donor selection. Many of these new approaches result in greater…”
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The composition of ectopic lymphoid structures suggests involvement of a local immune response in cardiac allograft vasculopathy by Huibers, Manon M.H., MSc, Gareau, Alison J., PhD, Vink, Aryan, MD, PhD, Kruit, Rianne, MSc, Feringa, Hannah, BSc, Beerthuijzen, Johanna M.T., BSc, Siera-de Koning, Erica, BSc, Peeters, Ton, BSc, Jonge, Nicolaas de, MD, PhD, de Weger, Roel A., PhD, Lee, Timothy D.G., PhD

“…Background Cardiac allograft vasculopathy (CAV) is a multifactorial pathology limiting the survival of cardiac transplants. The etiology of CAV is unclear, but…”
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HLA Genotype Imputation Results in Largely Accurate Epitope Mismatch Risk Categorization Across Racial Groups by Cohen, Gregory S, Gareau, Alison J, Kallarakal, Melissa A, Farooq, Tayyiaba, Bettinotti, Maria P, Sullivan, H Cliff, Madbouly, Abeer, Krummey, Scott M

“…Biomarkers that predict posttransplant alloimmunity could lead to improved long-term graft survival. Evaluation of the number of mismatched epitopes between…”
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Ticagrelor inhibits platelet–tumor cell interactions and metastasis in human and murine breast cancer by Gareau, Alison J., Brien, Colin, Gebremeskel, Simon, Liwski, Robert S., Johnston, Brent, Bezuhly, Michael

“…Activated platelets promote the proliferation and metastatic potential of cancer cells. Platelet activation is largely mediated through ADP engagement of…”
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Cyclosporine immunosuppression does not prevent the production of donor-specific antibody capable of mediating allograft vasculopathy by Gareau, Alison J., MSc, Nashan, Bjorn, MD, PhD, Hirsch, Gregory M., MD, Lee, Timothy D.G., PhD

“…Background Late cardiac graft rejection, primarily mediated by allograft vasculopathy (AV), remains a major limitation to cardiac transplantation, even in the…”
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Next‐generation sequencing identifies two novel HLA class II alleles, HLA‐DRB101:115 and HLA‐DRB114:224 by Abu‐Khader, Ahmad, Gareau, Alison J., Burns, Caitlyn, Khan, Faisal, Berka, Noureddine

“…We identified two novel HLA class II alleles by NGS, HLA‐DRB1*01:115 and HLA‐DRB1*14:224…”
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Promotion of Primary Murine Breast Cancer Growth and Metastasis by Adipose-Derived Stem Cells Is Reduced in the Presence of Autologous Fat Graft by Gebremeskel, Simon, Gencarelli, John, Gareau, Alison J., Levatte, Terry, Dugandzic, B.Sc, Anton, Johnston, Brent, Bezuhly, Michael

“…Cell-assisted lipotransfer involves enrichment of autologous fat with supraphysiologic numbers of adipose-derived stem cells to improve graft take…”
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Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies by Xu, Qingyong, Elrefaei, Mohamed, Taupin, Jean-Luc, Hitchman, Kelley M.K., Hiho, Steven, Gareau, Alison J., Iasella, Carlo J., Marrari, Marilyn, Belousova, Natalia, Bettinotti, Maria, Narula, Tathagat, Alvarez, Francisco, Sanchez, Pablo G., Levvey, Bronwyn, Westall, Glen, Snell, Gregory, Levine, Deborah J., Zeevi, Adriana, Roux, Antoine

“…Chronic lung allograft dysfunction (CLAD) is the major cause of adverse outcomes in lung transplant recipients. Multiple factors, such as infection,…”
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The identification of a novel HLA‐B allele, HLA‐B27:05:38 by Gareau, Alison J., Mostafa, Ahmed A., Stamm, Luz, Khan, Faisal, Berka, Noureddine

“…HLA‐B*27:05:38 differs from HLA‐B*27:05:02:01 by 2 mismatches in exon 3, resulting in 2 synonymous mutations…”
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Effect of Compound 21, a Selective Angiotensin II Type 2 Receptor Agonist, in a Murine Xenograft Model of Dupuytren Disease by Chisholm, Jessica, Gareau, Alison J., Byun, Stephanie, Paletz, Justin L., Tang, David, Williams, Jason, LeVatte, Terry, Bezuhly, Michael

“…Although surgical excision and intralesional collagenase injection are mainstays in Dupuytren disease treatment, no effective medical therapy exists for…”
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Identification of a novel HLA‐C allele, HLA‐C07:778, in an unrelated hematopoietic stem cell donor by Gareau, Alison J., Mostafa, Ahmed A., Williams, Jolene, Stamm, Luz, Berka, Noureddine

“…HLA‐C*07:778 differs from HLA‐C*07:01:01:01 by a single nonsynonymous nucleotide substitution at codon 263 (CAC→CAG)…”
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Pre-transplant AT1R antibodies correlate with early allograft rejection by Gareau, Alison J., Wiebe, Chris, Pochinco, Denise, Gibson, Ian W., Ho, Julie, Rush, David N., Nickerson, Peter W.

“…Studies investigating the potential pathogenic effects of non-HLA antibodies (Ab) have identified Ab against the angiotensin II type 1 receptor (AT1R-Ab) as a…”
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Pre-transplant AT 1 R antibodies correlate with early allograft rejection by Gareau, Alison J, Wiebe, Chris, Pochinco, Denise, Gibson, Ian W, Ho, Julie, Rush, David N, Nickerson, Peter W

“…Studies investigating the potential pathogenic effects of non-HLA antibodies (Ab) have identified Ab against the angiotensin II type 1 receptor (AT R-Ab) as a…”
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Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis by Rosin, Nicole L, Gareau, Alison J, Betsch, Devin, Falkenham, Alec, Sopel, Mryanda J, Lee, Timothy Dg, Légaré, Jean-Francois

“…Myocardial fibrosis is a pathological process that is characterized by disrupted regulation of extracellular matrix proteins resulting in permanent scarring of…”
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OR39 Public solicitation for a living kidney donor: Effects on the transplant waiting list and HLA laboratory workload by Gareau, Alison J., Khan, Faisal, Stamm, Luz, Berka, Noureddine

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P065A Missing recipient killer immunoglobulin like receptor (KIR) and donor human leukocyte antigen (HLA) interaction leads to higher incidence of chronic renal allograft failure by Adams, Brittin, Faridi, Rehan, Akhter, Ariz, Gareau, Alison J., Yilmaz, Serdar, Berka, Noureddine, Khan, Faisal

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