Search Results - "Garduno, B Maximiliano"
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Genome Sequencing Variations in the Octodon degus , an Unconventional Natural Model of Aging and Alzheimer's Disease
Published in Frontiers in aging neuroscience (30-06-2022)“…The degu ( ) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age…”
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How the forebrain transitions to adulthood: developmental plasticity markers in a long-lived rodent reveal region diversity and the uniqueness of adolescence
Published in Frontiers in neuroscience (22-02-2024)“…Maturation of the forebrain involves transitions from higher to lower levels of synaptic plasticity. The timecourse of these changes likely differs between…”
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Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions
Published in Molecular psychiatry (01-12-2023)“…Inhibitory interneurons are crucial to brain function and their dysfunction is implicated in neuropsychiatric conditions. Emerging evidence indicates that…”
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Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer's disease
Published in Acta neuropathologica communications (19-12-2022)“…The long-lived Chilean rodent (Octodon degus) has been reported to show spontaneous age-dependent neuropathology and cognitive impairments similar to those…”
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