Search Results - "Gardner, Matthew P.H."

Encoding and tracking of outcome-specific expectancy in the gustatory cortex of alert rats by Gardner, Matthew P H, Fontanini, Alfredo

“…In natural conditions, gustatory stimuli are typically expected. Anticipatory and contextual cues provide information that allows animals to predict the…”
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Rat Orbitofrontal Ensemble Activity Contains Multiplexed but Dissociable Representations of Value and Task Structure in an Odor Sequence Task by Zhou, Jingfeng, Gardner, Matthew P.H., Stalnaker, Thomas A., Ramus, Seth J., Wikenheiser, Andrew M., Niv, Yael, Schoenbaum, Geoffrey

“…The orbitofrontal cortex (OFC) has long been implicated in signaling information about expected outcomes to facilitate adaptive or flexible behavior. Current…”
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Effects of Cue-Triggered Expectation on Cortical Processing of Taste by Samuelsen, Chad L., Gardner, Matthew P.H., Fontanini, Alfredo

“…Animals are not passive spectators of the sensory world in which they live. In natural conditions they often sense objects on the bases of expectations…”
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Real-Time Value Integration during Economic Choice Is Regulated by Orbitofrontal Cortex by Gardner, Matthew P.H., Conroy, Jessica C., Sanchez, Davied C., Zhou, Jingfeng, Schoenbaum, Geoffrey

“…Neural correlates implicate the orbitofrontal cortex (OFC) in value-based or economic decision making [1–3]. Yet inactivation of OFC in rats performing a…”
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Evolving schema representations in orbitofrontal ensembles during learning by Zhou, Jingfeng, Jia, Chunying, Montesinos-Cartagena, Marlian, Gardner, Matthew P. H., Zong, Wenhui, Schoenbaum, Geoffrey

“…How do we learn about what to learn about? Specifically, how do the neural elements in our brain generalize what has been learned in one situation to recognize…”
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Rethinking dopamine as generalized prediction error by Gardner, Matthew P H, Schoenbaum, Geoffrey, Gershman, Samuel J

“…Midbrain dopamine neurons are commonly thought to report a reward prediction error (RPE), as hypothesized by reinforcement learning (RL) theory. While this…”
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Complementary Task Structure Representations in Hippocampus and Orbitofrontal Cortex during an Odor Sequence Task by Zhou, Jingfeng, Montesinos-Cartagena, Marlian, Wikenheiser, Andrew M., Gardner, Matthew P.H., Niv, Yael, Schoenbaum, Geoffrey

“…Both hippocampus (HPC) and orbitofrontal cortex (OFC) have been shown to be critical for behavioral tasks that require use of an internal model or cognitive…”
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Spatial Representations in Rat Orbitofrontal Cortex by Wikenheiser, Andrew M, Gardner, Matthew P H, Mueller, Lauren E, Schoenbaum, Geoffrey

“…The orbitofrontal cortex (OFC) and hippocampus share striking cognitive and functional similarities. As a result, both structures have been proposed to encode…”
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The Orbitofrontal Cartographer by Gardner, Matthew P. H., Schoenbaum, Geoffrey

“…Theories of orbitofrontal cortex (OFC) function have evolved substantially over the last few decades. There is now a general consensus that the OFC is…”
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The role of the lateral orbitofrontal cortex in creating cognitive maps by Costa, Kauê Machado, Scholz, Robert, Lloyd, Kevin, Moreno-Castilla, Perla, Gardner, Matthew P. H., Dayan, Peter, Schoenbaum, Geoffrey

“…We use mental models of the world—cognitive maps—to guide behavior. The lateral orbitofrontal cortex (lOFC) is typically thought to support behavior by…”
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Processing in Lateral Orbitofrontal Cortex Is Required for Estimating Subjective Preference during Initial, but Not Established, Economic Choice by Gardner, Matthew P.H., Sanchez, Davied, Conroy, Jessica C., Wikenheiser, Andrew M., Zhou, Jingfeng, Schoenbaum, Geoffrey

“…The orbitofrontal cortex (OFC) is proposed to be critical to economic decision making. Yet one can inactivate OFC without affecting well-practiced choices. One…”
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Past experience shapes the neural circuits recruited for future learning by Sharpe, Melissa J., Batchelor, Hannah M., Mueller, Lauren E., Gardner, Matthew P. H., Schoenbaum, Geoffrey

“…Experimental research controls for past experience, yet prior experience influences how we learn. Here, we tested whether we could recruit a neural population…”
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Neuroscience: From Sensory Discrimination to Choice in Gustatory Cortex by Gardner, Matthew P.H., Schoenbaum, Geoffrey

“…Sensory areas have been shown to be influenced by higher-order cognitive processes. Yet how do these top-down processes affect decisions? A recent study has…”
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Lateral Orbitofrontal Inactivation Dissociates Devaluation-Sensitive Behavior and Economic Choice by Gardner, Matthew P.H., Conroy, Jessica S., Shaham, Michael H., Styer, Clay V., Schoenbaum, Geoffrey

“…How do we choose between goods that have different subjective values, like apples and oranges? Neuroeconomics proposes that this is done by reducing complex…”
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Anterior cingulate neurons signal neutral cue pairings during sensory preconditioning by Hart, Evan E., Gardner, Matthew P.H., Schoenbaum, Geoffrey

“…Of all frontocortical subregions, the anterior cingulate cortex (ACC) has perhaps the most overlapping theories of function.1–3 Recording studies in rats,…”
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Processing in Lateral Orbitofrontal Cortex Is Required to Estimate Subjective Preference during Initial, but Not Established, Economic Choice by Gardner, Matthew P.H., Sanchez, Davied, Conroy, Jessica C., Wikenheiser, Andrew M., Zhou, Jingfeng, Schoenbaum, Geoffrey

“…The orbitofrontal cortex (OFC) is proposed to be critical to economic decision making. Yet one can inactivate OFC without affecting well-practiced choices. One…”
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Calcium activity is a degraded estimate of spikes by Hart, Evan E., Gardner, Matthew P.H., Panayi, Marios C., Kahnt, Thorsten, Schoenbaum, Geoffrey

“…Recording action potentials extracellularly during behavior has led to fundamental discoveries regarding neural function—hippocampal neurons respond to…”
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Is the core function of orbitofrontal cortex to signal values or make predictions? by Zhou, Jingfeng, Gardner, Matthew PH, Schoenbaum, Geoffrey

“…One dominant hypothesis about the function of the orbitofrontal cortex (OFC) is that the OFC signals the subjective values of possible outcomes to other brain…”
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Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors by Maes, Etienne J. P, Sharpe, Melissa J., Usypchuk, Alexandra A., Lozzi, Megan, Chang, Chun Yun, Gardner, Matthew P. H., Schoenbaum, Geoffrey, Iordanova, Mihaela D.

“…Reward-evoked dopamine transients are well established as prediction errors. However, the central tenet of temporal difference accounts—that similar transients…”
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Brief, But Not Prolonged, Pauses in the Firing of Midbrain Dopamine Neurons Are Sufficient to Produce a Conditioned Inhibitor by Chang, Chun Yun, Gardner, Matthew P H, Conroy, Jessica C, Whitaker, Leslie R, Schoenbaum, Geoffrey

“…Prediction errors are critical for associative learning. In the brain, these errors are thought to be signaled, in part, by midbrain dopamine neurons. However,…”
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