Search Results - "Gardner, Julia"

Preoperative Staphylococcus Aureus Screening and Targeted Decolonization in Cardiac Surgery by Saraswat, Manoj K., MHS, Magruder, Jonathan T., MD, Crawford, Todd C., MD, Gardner, Julia M., BSN, Duquaine, Damon, MPH, Sussman, Marc S., MD, Maragakis, Lisa L., MD, MPH, Whitman, Glenn J., MD

“…Background We assessed the impact of preoperative Staphylococcus aureus screening and targeted decolonization on the incidence of postoperative…”
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Location bias contributes to functionally selective responses of biased CXCR3 agonists by Eiger, Dylan Scott, Boldizsar, Noelia, Honeycutt, Christopher Cole, Gardner, Julia, Kirchner, Stephen, Hicks, Chloe, Choi, Issac, Pham, Uyen, Zheng, Kevin, Warman, Anmol, Smith, Jeffrey S., Zhang, Jennifer Y., Rajagopal, Sudarshan

“…Some G protein-coupled receptor (GPCR) ligands act as “biased agonists” that preferentially activate specific signaling transducers over others. Although GPCRs…”
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Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial by Sime, Fekade Bruck, Roberts, Michael S, Tiong, Ing Soo, Gardner, Julia H, Lehman, Sheila, Peake, Sandra L, Hahn, Uwe, Warner, Morgyn S, Roberts, Jason A

“…The objectives of this study were to describe piperacillin exposure in febrile neutropenia patients and determine whether therapeutic drug monitoring (TDM) can…”
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Safety and Efficacy of Prophylactic Levofloxacin in Pediatric and Adult Hematopoietic Stem Cell Transplantation Patients by Gardner, Julia C., Courter, Joshua D., Dandoy, Christopher E., Davies, Stella M., Teusink-Cross, Ashley

“…•Levofloxacin decreases the incidence of bloodstream infections after transplantation.•Levofloxacin prophylaxis did not increase the risk of Clostridium…”
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Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies by Sime, Fekade Bruck, Roberts, Michael S, Tiong, Ing Soo, Gardner, Julia H, Lehman, Sheila, Peake, Sandra L, Hahn, Uwe, Warner, Morgyn S, Roberts, Jason A

“…While guidelines recommend empirical cefepime therapy in febrile neutropenia, the mortality benefit of cefepime has been controversial. In light of this,…”
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Staphylococcus Aureus Prevention Strategies in Cardiac Surgery: A Cost-Effectiveness Analysis by Hong, Jonathan C., Saraswat, Manoj K., Ellison, Trevor A., Magruder, J. Trent, Crawford, Todd, Gardner, Julia M., Padula, William V., Whitman, Glenn J.

“…Cardiac surgery patients colonized with Staphylococcus aureus have a greater risk of surgical site infection (SSI). The purpose of this study was to evaluate…”
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A comprehensive literature scoping review of infection prevention and control methods for viral-mediated gene therapies by Blind, Jill E, Ghosh, Sumit, Niese, Taylor D, Gardner, Julia C, Stack-Simone, Stephanie, Dean, Abigail, Washam, Matthew

“…This comprehensive literature scoping review outlines available infection prevention and control (IPC) methods for viral-mediated gene therapies and provides…”
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Why remove injectable promethazine from the formulary? by Moodley, Jenna M., Gardner, Julia C., Sheridan, Daniel J.

“…Promethazine is a phenothiazine derivative and H1 receptor blocking agent with antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic…”
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Food as medicine? Exploring the impact of providing healthy foods on adherence and clinical and economic outcomes by Chen, Aleda M.H., Draime, Juanita A., Berman, Sarah, Gardner, Julia, Krauss, Zach, Martinez, Joe

“…Chronic disease prevalence is increasing. Adherence to dietary guidelines is low (<50%) despite positive impacts in disease progression, clinical outcomes, and…”
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A Qualitative Exploration of Pregnancy Experience With a Nutrient-Dense, Plant-Rich Dietary Pattern: A Pilot Study by McNelly, Allison P., Eaves, Emery R., Christine Gardner, Julia, Wetzel, Wendy S., Sutliffe, Jay T.

“…Introduction: A nutrient-dense, plant-rich diet may be promising as a nutrition intervention for pregnant women for a number of factors. Factors include the…”
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Protocol and Preliminary Results of the Nutritarian Women’s Health Study: A Longitudinal Effectiveness-Implementation Hybrid Study Assessing Dietary Intake and Health Outcomes by Sutliffe, Jay T., Gardner, Julia C., Wetzel, Wendy S., Carnot, Mary Jo, Adams, Alison E. M.

“…Whole-food plant-rich dietary patterns have been shown to be associated with significant health benefits and disease-risk reduction. One such program, which…”
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Impact of a 6-Month Micronutrient-Dense Plant-Rich Nutrition Intervention on Health and Well-Being at the Worksite by Adams, Alison, Fortin, Tricia, Wetzel, Wendy S., Carnot, Mary Jo, Gorman, Michelle M., Gardner, Julia C., Sutliffe, Jay T., Sutliffe, Chloe A.

“…This nonrandomized pilot study utilized the health belief model and the theory of planned behavior to assess the effectiveness of perceived behavioral control…”
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GPCR systems pharmacology: a different perspective on the development of biased therapeutics by Eiger, Dylan Scott, Pham, Uyen, Gardner, Julia, Hicks, Chloe, Rajagopal, Sudarshan

“…G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and are the target of approximately one-third of all Food and Drug…”
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Location bias: A “Hidden Variable” in GPCR pharmacology by Eiger, Dylan Scott, Hicks, Chloe, Gardner, Julia, Pham, Uyen, Rajagopal, Sudarshan

“…Abstract G protein‐coupled receptors (GPCRs) are the largest family of transmembrane receptors and primarily signal through two main effector proteins: G…”
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Biased agonism at chemokine receptors by Eiger, Dylan Scott, Boldizsar, Noelia, Honeycutt, Christopher Cole, Gardner, Julia, Rajagopal, Sudarshan

“…In the human chemokine system, interactions between the approximately 50 known endogenous chemokine ligands and 20 known chemokine receptors (CKRs) regulate a…”
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Sympathetic and Parasympathetic Regulation of NF‐κB by GPCRs through the modulation of interactions between p65/RelA and the β‐arrestins by Honeycutt, Christopher, Eiger, Dylan, Boldizsar, Noelia, Gardner, Julia, Rajagopal, Sudarshan

“…Study Objective: This project sought to elucidate the biological mechanisms and physiological significance of β2 adrenergic receptor (B2AR)‐ and M1 muscarinic…”
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Receptor Endocytosis as a Mechanism of Biased Agonism at CXCR3 by Boldizsar, Noelia, Eiger, Dylan, Honeycutt, Cole, Gardner, Julia, Rajagopal, Sudarshan

“…G Protein Coupled Receptors (GPCRs) are the largest class of receptors in the human genome. They are expressed in virtually every cell type and are implicated…”
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Differential GRK Recruitment and the Phosphorylation Barcode as a Mechanism for Biased Agonism at G Protein‐Coupled Receptors by Gardner, Julia, Eiger, Dylan, Honeycutt, Christopher, Boldizsar, Noelia, Choi, Issac, Rajagopal, Sudarshan

“…G Protein‐Coupled Receptors (GPCRs) are the largest and most diverse family of cell receptors in the human genome and account for ~30% of all FDA‐approved…”
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Location Bias of G Protein‐Coupled Receptor Kinases Promotes Biased Signaling at CXCR3 by Hicks, Chloe N., Eiger, Dylan, Gardner, Julia, Boldizsar, Noelia, Honeycutt, Cole, Choi, Issac, Rajagopal, Sudarshan

“…G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors and are known to canonically signal through two main effector proteins: G…”
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Bone marrow fibrosis impact on response to azacitidine in myelodysplastic syndromes by Shahidi, Roya, Mohamed, Muhajir, Sharma, Archana, Heenan, Jessica, Gardner, Julia, Hitchins, Sam

“…Bone marrow fibrosis in myelodysplastic syndromes (MDS) has been associated with poor outcome. However, these studies were conducted prior to the widespread…”
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