Search Results - "Gardner, Humphrey A."

A Crucial Role for Primary Cilia in Cortical Morphogenesis by Willaredt, Marc A, Hasenpusch-Theil, Kerstin, Gardner, Humphrey A. R, Kitanovic, Igor, Hirschfeld-Warneken, Vera C, Gojak, Christian P, Gorgas, Karin, Bradford, C. Lulu, Spatz, Joachim, Wolfl, Stefan, Theil, Thomas, Tucker, Kerry L

“…Primary cilia are important sites of signal transduction involved in a wide range of developmental and postnatal functions. Proteolytic processing of the…”
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Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis by POZZI, Ambra, LEVINE, Wendy F, GARDNER, Humphrey A

“…Angiogenesis is essential for tumor growth and blocking this process might be a valid tool for the control of cancer growth. We showed previously that tumor…”
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Primary cilia are critical for tracheoesophageal septation by Fitzsimons, Lindsey Avery, Tasouri, Evangelia, Willaredt, Marc August, Stetson, Daniel, Gojak, Christian, Kirsch, Joachim, Gardner, Humphrey A. R., Gorgas, Karin, Tucker, Kerry L.

“…Introduction Primary cilia play pivotal roles in the patterning and morphogenesis of a wide variety of organs during mammalian development. Here we examined…”
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Elucidation of Mechanisms of Ceftazidime Resistance among Clinical Isolates of Pseudomonas aeruginosa by Using Genomic Data by Kos, Veronica N, McLaughlin, Robert E, Gardner, Humphrey A

“…Ceftazidime is one of the few cephalosporins with activity against Pseudomonas aeruginosa Using whole-genome comparative analysis, we set out to determine the…”
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Identification of unique in-frame deletions in OprD among clinical isolates of Pseudomonas aeruginosa by Kos, Veronica N., McLaughlin, Robert E., Gardner, Humphrey A.

“…A large percentage of Pseudomonas aeruginosa clinical isolates have been noted to be resistant to carbapenems due to loss of function of the OprD porin, the…”
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Control of Postnatal Apoptosis in the Neocortex byRhoA-Subfamily GTPases Determines Neuronal Density by Sanno, Hitomi, Shen, Xiao, Kuru, Nilgun, Bormuth, Ingo, Bobsin, Kristin, Gardner, Humphrey A. R, Komljenovic, Dorde, Tarabykin, Victor, Erzurumlu, Reha S, Tucker, Kerry L

“…Apoptosis of neurons in the maturing neocortex has been recorded in a wide variety of mammals, but very little is known about its effects on cortical…”
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αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse by Hahm, Kyungmin, Lukashev, Matvey E, Luo, Yi, Yang, William J, Dolinski, Brian M, Weinreb, Paul H, Simon, Kenneth J, Chun Wang, Li, Leone, Diane R, Lobb, Roy R, McCrann, Donald J, Allaire, Normand E, Horan, Gerald S, Fogo, Agnes, Kalluri, Raghu, Shield, Charles F, Sheppard, Dean, Gardner, Humphrey A, Violette, Shelia M

“…The transforming growth factor (TGF)-β-inducible integrin αvβ6 is preferentially expressed at sites of epithelial remodeling and has been shown to bind and…”
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Control of postnatal apoptosis in the neocortex by RhoA-subfamily GTPases determines neuronal density by Sanno, Hitomi, Shen, Xiao, Kuru, Nilgün, Bormuth, Ingo, Bobsin, Kristin, Gardner, Humphrey A R, Komljenovic, Dorde, Tarabykin, Victor, Erzurumlu, Reha S, Tucker, Kerry L

“…Apoptosis of neurons in the maturing neocortex has been recorded in a wide variety of mammals, but very little is known about its effects on cortical…”
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Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization by Pozzi, Ambra, Moberg, Philip E., Miles, Lindsey A., Wagner, Simone, Soloway, Paul, Gardner, Humphrey A.

“…Integrin α1β1 is a collagen receptor abundantly expressed on microvascular endothelial cells. As well as being the only collagen receptor able to activate the…”
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Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism by Van Aarsen, Louise A Koopman, Leone, Diane R, Ho, Steffan, Dolinski, Brian M, McCoon, Patricia E, LePage, Doreen J, Kelly, Rebecca, Heaney, Glenna, Rayhorn, Paul, Reid, Carl, Simon, Kenneth J, Horan, Gerald S, Tao, Nianjun, Gardner, Humphrey A, Skelly, Marilyn M, Gown, Allen M, Thomas, Gareth J, Weinreb, Paul H, Fawell, Stephen E, Violette, Shelia M

“…The alpha(v)beta(6) integrin is up-regulated on epithelial malignancies and has been implicated in various aspects of cancer progression. Immunohistochemical…”
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Multiple essential roles for primary cilia in heart development by Willaredt, Marc August, Gorgas, Karin, Gardner, Humphrey A R, Tucker, Kerry L

“…The primary cilium is a microtubule-based, plasma membrane-ensheathed protrusion projecting from the basal bodies of almost all cell types in the mammalian…”
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Integrin α1β1 Mediates a Unique Collagen-Dependent Proliferation Pathway in vivo by Pozzi, Ambra, Wary, Kishore K., Giancotti, Filippo G., Gardner, Humphrey A.

“…Activation of integrins upon binding to extracellular matrix proteins is believed to be a crucial step for the regulation of cell survival and proliferation…”
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Expression of Matrix Metalloprotease-2-Cleaved Laminin-5 in Breast Remodeling Stimulated by Sex Steroids by Giannelli, Gianluigi, Pozzi, Ambra, Stetler-Stevenson, William G., Gardner, Humphrey A., Quaranta, Vito

“…The extracellular matrix plays an important role in breast remodeling. We have shown that matrix metalloprotease-2 (MMP2) cleaves laminin-5 (Ln-5), a basement…”
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Antibody-Mediated Blockade of Integrin αvβ6Inhibits Tumor Progression In vivo by a Transforming Growth Factor-β-Regulated Mechanism by KOOPMAN VAN AARSEN, Louise A, LEONE, Diane R, SIMON, Kenneth J, HORAN, Gerald S, NIANJUN TAO, GARDNER, Humphrey A, SKELLY, Marilyn M, GOWN, Allen M, THOMAS, Gareth J, WEINREB, Paul H, FAWELL, Stephen E, VIOLETTE, Shelia M, HO, Steffan, DOLINSKI, Brian M, MCCOON, Patricia E, LEPAGE, Doreen J, KELLY, Rebecca, HEANEY, Glenna, RAYHORN, Paul, REID, Carl

“…Abstract The αvβ6 integrin is up-regulated on epithelial malignancies and has been implicated in various aspects of cancer progression. Immunohistochemical…”
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Elevated Matrix Metalloprotease and Angiostatin Levels in Integrin α 1 Knockout Mice Cause Reduced Tumor Vascularization by Pozzi, Ambra, Moberg, Philip E., Miles, Lindsey A., Wagner, Simone, Soloway, Paul, Gardner, Humphrey A.

“…Integrin α 1β 1 is a collagen receptor abundantly expressed on microvascular endothelial cells. As well as being the only collagen receptor able to activate…”
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Predictive value of fine-needle aspiration of the thyroid in the classification of follicular lesions by Gardner, H A, Ducatman, B S, Wang, H H

“…Fine-needle aspiration has been less valuable in the diagnosis of follicular lesions than for other neoplasms of the thyroid. It has been observed that…”
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Overexpression of the αvβ6 Integrin in Endometrial Cancer by Hecht, Jonathan L., Dolinski, Brian M., Gardner, Humphrey A., Violette, Shelia M., Weinreb, Paul H.

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Treatment of murine lupus with cDNA encoding IFN-γR/Fc by Lawson, Brian R., Prud’homme, Gerald J., Chang, Yigang, Gardner, Humphrey A., Kuan, Jason, Kono, Dwight H., Theofilopoulos, Argyrios N.

“…IFN-γ, a pleiotropic cytokine, is a key effector molecule in the pathogenesis of several autoimmune diseases, including lupus. Importantly, deletion of IFN-γ…”
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Antibody-Mediated Blockade of Integrin alpha sub(v) beta sub(6) Inhibits Tumor Progression In vivo by a Transforming Growth Factor- beta -Regulated Mechanism by Koopman Van Aarsen, Louise A, Leone, Diane R, Ho, Steffan, Dolinski, Brian M, McCoon, Patricia E, LePage, Doreen J, Kelly, Rebecca, Heaney, Glenna, Rayhorn, Paul, Reid, Carl, Simon, Kenneth J, Horan, Gerald S, Tao, Nianjun, Gardner, Humphrey A, Skelly, Marilyn M, Gown, Allen M, Thomas, Gareth J, Weinreb, Paul H, Fawell, Stephen E, Violette, Shelia M

“…The alpha sub(v) beta sub(6) integrin is up-regulated on epithelial malignancies and has been implicated in various aspects of cancer progression…”
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Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse by Hahm, Kyungmin, Lukashev, Matvey E, Luo, Yi, Yang, William J, Dolinski, Brian M, Weinreb, Paul H, Simon, Kenneth J, Chun Wang, Li, Leone, Diane R, Lobb, Roy R, McCrann, Donald J, Allaire, Normand E, Horan, Gerald S, Fogo, Agnes, Kalluri, Raghu, Shield, 3rd, Charles F, Sheppard, Dean, Gardner, Humphrey A, Violette, Shelia M

“…The transforming growth factor (TGF)-beta-inducible integrin alpha v beta6 is preferentially expressed at sites of epithelial remodeling and has been shown to…”
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