Search Results - "Gardner, Andrea"
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Mathematical modelling of the dynamics of image-informed tumor habitats in a murine model of glioma
Published in Scientific reports (20-02-2023)“…Tumors exhibit high molecular, phenotypic, and physiological heterogeneity. In this effort, we employ quantitative magnetic resonance imaging (MRI) data to…”
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Author Correction: Mathematical modelling of the dynamics of image-informed tumor habitats in a murine model of glioma
Published in Scientific reports (22-05-2023)Get full text
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Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations
Published in NPJ systems biology and applications (17-10-2024)“…Intratumor heterogeneity reduces treatment efficacy and complicates our understanding of tumor progression and there is a pressing need to understand the…”
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KS-Detect - Validation of Solar Thermal PCR for the Diagnosis of Kaposi's Sarcoma Using Pseudo-Biopsy Samples
Published in PloS one (22-01-2016)“…Resource-limited settings present unique engineering challenges for medical diagnostics. Diagnosis is often needed for those unable to reach central healthcare…”
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Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer
Published in Physical biology (20-11-2020)“…A significant challenge in the field of biomedicine is the development of methods to integrate the multitude of dispersed data sets into comprehensive…”
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Integrating Quantitative Assays with Biologically Based Mathematical Modeling for Predictive Oncology
Published in iScience (18-12-2020)“…We provide an overview on the use of biological assays to calibrate and initialize mechanism-based models of cancer phenomena. Although artificial intelligence…”
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Effects of Integrating Mathematical Concepts into a Nutrition Unit in the Animal Science Curriculum
Published in Journal of research in technical careers (09-05-2017)“…Achievement test scores in mathematics have been a concern among educators for many years. Teaching contextualized mathematics has been found to be effective…”
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TRANSITIONING FROM PARENTERAL PROSTACYCLIN THERAPY TO ORAL SELEXIPAG IN PULMONARY ARTERIAL HYPERTENSION
Published in Chest (01-10-2021)Get full text
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Integration of quantitative methods and mathematical approaches for the modeling of cancer cell proliferation dynamics
Published in American Journal of Physiology: Cell Physiology (01-02-2023)“…Physiological processes rely on the control of cell proliferation, and the dysregulation of these processes underlies various pathological conditions,…”
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Functionalized Lineage Tracing for the Study and Manipulation of Heterogeneous Cell Populations
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…The ability to track and isolate unique cell lineages from large heterogeneous populations increases the resolution at which cellular processes can be…”
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Abstract 5379: Deep learning enables label-free tracking of heterogeneous subpopulations
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Observing and quantifying the proliferation of subpopulations in cancer is key to understanding how heterogeneous groups of cells interact and respond to…”
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Barriers to HIV Testing: Patient and Provider Perspectives in the Deep South
Published in AIDS and behavior (01-04-2019)“…Although CDC guidelines call for universal, “opt-out” HIV testing, barriers to testing continue to exist throughout the United States, with the rural South…”
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Abstract B037: ClonMapper Duo: An scRNAseq compatible lineage tracing method to track cell-cell fusion at single-cell resolution
Published in Cancer research (Chicago, Ill.) (01-02-2024)“…Spontaneous cell-cell fusion in cancer can generate genetic heterogeneity and often leads to more pathological phenotypes. While the consequences of cell-cell…”
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Abstract 122: The subclonal dynamics of gross ploidy alterations in TNBC cells under chemotherapeutic pressure
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Solid tumors such as triple-negative breast cancer (TNBC) have characteristically high rates of aneuploidy and polyploidy. Chromosome-level aneuploidies are…”
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A portable device for nucleic acid quantification powered by sunlight, a flame or electricity
Published in Nature biomedical engineering (01-09-2018)“…A decentralized approach to diagnostics can decrease the time to treatment of infectious diseases in resource-limited settings, yet most modern diagnostic…”
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Abstract B017: Homotypic cell-cell fusion in TNBC cells downregulates cancer testis antigen MAGEC2 and increases therapeutic sensitivity to paclitaxel and doxorubicin
Published in Cancer research (Chicago, Ill.) (15-05-2022)“…This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Proffered Abstracts section (PR007) of the…”
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Abstract PR007: Homotypic cell-cell fusion in TNBC cells downregulates cancer testis antigen MAGEC2 and increases therapeutic sensitivity to paclitaxel and doxorubicin
Published in Cancer research (Chicago, Ill.) (15-05-2022)“…Cell-cell fusion between cancer cells and genetically mismatched populations has been shown to generate genotypic diversity and more pathological phenotypes…”
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Simplified Detection of Epstein-Barr Virus for Diagnosis of Endemic Burkitt Lymphoma
Published in Blood advances (28-06-2022)Get full text
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LAMP-enabled diagnosis of Kaposi's sarcoma for sub-Saharan Africa
Published in Science advances (13-01-2023)“…Kaposi's sarcoma (KS) is an endothelial cancer caused by the Kaposi's sarcoma-associated herpesvirus (KSHV) and is one of the most common cancers in…”
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Solar-thermal complex sample processing for nucleic acid based diagnostics in limited resource settings
Published in Biomedical optics express (01-05-2016)“…The use of point-of-care (POC) devices in limited resource settings where access to commonly used infrastructure, such as water and electricity, can be…”
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