Search Results - "Gardiner, Woodrow D"
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Real-time environmental surveillance of SARS-CoV-2 aerosols
Published in Nature communications (10-07-2023)“…Real-time surveillance of airborne SARS-CoV-2 virus is a technological gap that has eluded the scientific community since the beginning of the COVID-19…”
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A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter
Published in Translational neurodegeneration (12-05-2023)“…In support of this, Aβ oligomer reduction in an AD mouse model leads to memory preservation [2, 3], and clinical benefit was in trials of lecanemab, which…”
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Effect of escitalopram on Aβ levels and plaque load in an Alzheimer mouse model
Published in Neurology (10-11-2020)“…BACKGROUNDSeveral neurotransmitter receptors activate signaling pathways that alter processing of the amyloid precursor protein (APP) into β-amyloid (Aβ)…”
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4
Sex-dependent effects of acute stress on amyloid-β in male and female mice
Published in Brain (London, England : 1878) (01-06-2023)“…Abstract The risk of developing Alzheimer’s disease is mediated by a combination of genetics and environmental factors, such as stress, sleep abnormalities and…”
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Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease
Published in Journal of neurochemistry (01-03-2021)“…Amyloid‐β (Aβ) peptide aggregation into soluble oligomers and insoluble plaques is a precipitating event in the pathogenesis of Alzheimer's disease (AD). Given…”
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6
Pimavanserin, a 5HT 2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease
Published in Journal of neurochemistry (01-03-2021)“…Amyloid-β (Aβ) peptide aggregation into soluble oligomers and insoluble plaques is a precipitating event in the pathogenesis of Alzheimer's disease (AD). Given…”
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7
Rapid Direct Detection of SARS-CoV‑2 Aerosols in Exhaled Breath at the Point of Care
Published in ACS sensors (25-08-2023)“…Airborne transmission via virus-laden aerosols is a dominant route for the transmission of respiratory diseases, including severe acute respiratory syndrome…”
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