Search Results - "Garden, Padric"
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Ultrasensitive Detection of Attomolar Protein Concentrations by Dropcast Single Molecule Assays
Published in Journal of the American Chemical Society (15-07-2020)“…Measurements of very low levels of biomolecules, including proteins and nucleic acids, remain a critical challenge in many clinical diagnostic applications due…”
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Single-molecule analysis of nucleic acid biomarkers – A review
Published in Analytica chimica acta (08-06-2020)“…Nucleic acids are important biomarkers for disease detection, monitoring, and treatment. Advances in technologies for nucleic acid analysis have enabled…”
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Single Molecule Protein Detection with Attomolar Sensitivity Using Droplet Digital Enzyme-Linked Immunosorbent Assay
Published in ACS nano (25-08-2020)“…Many proteins are present at low concentrations in biological samples, and therefore, techniques for ultrasensitive protein detection are necessary. To…”
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4
Transcription Factor Based Small‐Molecule Sensing with a Rapid Cell Phone Enabled Fluorescent Bead Assay
Published in Angewandte Chemie International Edition (23-11-2020)“…Recently, allosteric transcription factors (TFs) were identified as a novel class of biorecognition elements for in vitro sensing, whereby an indicator of the…”
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5
Plasma IL-6 changes correlate to PD-1 inhibitor responses in NSCLC
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundBlood-based biomarkers of anti-solid tumor immune checkpoint blockade (ICB) response are lacking. We hypothesized that changes in systemic cytokine…”
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6
Simplified Digital Enzyme-Linked Immunosorbent Assay Using Tyramide Signal Amplification and Fibrin Hydrogels
Published in ACS sensors (23-10-2020)“…Many protein biomarkers occur at very low concentrations in biofluids like blood and saliva, and ultrasensitive detection methods are required in order to…”
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Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer
Published in Cancer discovery (02-06-2022)“…Altered RNA expression of repetitive sequences and retrotransposition are frequently seen in colorectal cancer, implicating a functional importance of repeat…”
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8
Transcription Factor Based Small‐Molecule Sensing with a Rapid Cell Phone Enabled Fluorescent Bead Assay
Published in Angewandte Chemie (23-11-2020)“…Recently, allosteric transcription factors (TFs) were identified as a novel class of biorecognition elements for in vitro sensing, whereby an indicator of the…”
Get full text
Journal Article