Search Results - "Garden, Oliver A"
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ACVIM consensus statement on the treatment of immune‐mediated hemolytic anemia in dogs
Published in Journal of veterinary internal medicine (01-05-2019)“…Immune‐mediated hemolytic anemia (IMHA) causes severe anemia in dogs and is associated with considerable morbidity and mortality. Treatment with various…”
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ACVIM consensus statement on the diagnosis of immune‐mediated hemolytic anemia in dogs and cats
Published in Journal of veterinary internal medicine (01-03-2019)“…Immune‐mediated hemolytic anemia (IMHA) is an important cause of morbidity and mortality in dogs. IMHA also occurs in cats, although less commonly. IMHA is…”
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Serum Biochemical Phenotypes in the Domestic Dog
Published in PloS one (26-02-2016)“…The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference…”
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Immunoregulatory Cells in Myasthenia Gravis
Published in Frontiers in neurology (15-12-2020)“…Myasthenia gravis (MG) is a T cell-dependent, B-cell mediated autoimmune disease caused by antibodies against the nicotinic acetylcholine receptor or other…”
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Exploring the role of immune checkpoint inhibitors in the etiology of myasthenia gravis and Lambert-Eaton myasthenic syndrome: A systematic review
Published in Frontiers in neurology (09-01-2023)“…While immune checkpoint inhibitors (ICIs) have been revolutionary in the treatment of cancer, their administration has been associated with a variety of…”
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Clinical efficacy of prebiotics and glycosaminoglycans versus placebo In dogs with food responsive enteropathy receiving a hydrolyzed diet: A pilot study
Published in PloS one (21-10-2021)“…Induction of remission is easily achieved with dietary treatment in dogs diagnosed with Food Responsive Chronic Diarrhea (FRD). Administration of prebiotics…”
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A Systematic Review of the Potential Implication of Infectious Agents in Myasthenia Gravis
Published in Frontiers in neurology (14-06-2021)“…Myasthenia gravis (MG) is an autoimmune disorder of unknown etiology in most patients, in which autoantibodies target components of neuromuscular junctions and…”
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Characterisation of the Immunophenotype of Dogs with Primary Immune-Mediated Haemolytic Anaemia
Published in PloS one (12-12-2016)“…Immune-mediated haemolytic anaemia (IMHA) is reported to be the most common autoimmune disease of dogs, resulting in significant morbidity and mortality in…”
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ACVIM consensus statement on the diagnosis of immune thrombocytopenia in dogs and cats
Published in Journal of veterinary internal medicine (01-07-2024)“…Immune thrombocytopenia (ITP) is the most common acquired primary hemostatic disorder in dogs. Immune thrombocytopenia less commonly affects cats but is an…”
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Breed-specific hematological phenotypes in the dog: a natural resource for the genetic dissection of hematological parameters in a mammalian species
Published in PloS one (25-11-2013)“…Remarkably little has been published on hematological phenotypes of the domestic dog, the most polymorphic species on the planet. Information on the signalment…”
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ACVIM consensus statement on the treatment of immune thrombocytopenia in dogs and cats
Published in Journal of veterinary internal medicine (01-07-2024)“…Management of immune thrombocytopenia (ITP) in dogs and cats is evolving, but there are no evidence‐based guidelines to assist clinicians with treatment…”
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Missed, Not Missing: Phylogenomic Evidence for the Existence of Avian FoxP3
Published in PloS one (03-03-2016)“…The Forkhead box transcription factor FoxP3 is pivotal to the development and function of regulatory T cells (Tregs), which make a major contribution to…”
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Clinical features and outcome of acquired myasthenia gravis in 94 dogs
Published in Journal of veterinary internal medicine (01-09-2021)“…Background Factors known to be associated with outcome of acquired myasthenia gravis (MG) in dogs are limited. Hypothesis/Objectives Of dogs with MG, advancing…”
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Dissecting the regulatory microenvironment of a large animal model of non-Hodgkin lymphoma: evidence of a negative prognostic impact of FOXP3+ T cells in canine B cell lymphoma
Published in PloS one (13-08-2014)“…The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response…”
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Bacterial Killing Activity of Polymorphonuclear Myeloid-Derived Suppressor Cells Isolated From Tumor-Bearing Dogs
Published in Frontiers in immunology (10-10-2019)“…Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are implicated in the progression and outcome of a variety of pathological states, from cancer…”
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Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma
Published in PloS one (25-08-2016)“…Feline oral squamous cell carcinoma (FOSCC) is an aggressive neoplasm in cats. Little is known about the possible molecular mechanisms that may be involved in…”
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Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry
Published in Journal of veterinary diagnostic investigation (01-05-2018)“…Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large…”
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Regulatory T-cell–intrinsic amphiregulin is dispensable for suppressive function
Published in Journal of allergy and clinical immunology (01-06-2016)“…KO cocultures, with neither an intrinsic nor an extrinsic source of amphiregulin in the cultures, showed potent suppression (Fig 2, B and C). [...]recombinant…”
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Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation
Published in Frontiers in oncology (06-03-2020)“…Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on…”
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MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR
Published in The Journal of immunology (1950) (15-12-2015)“…CD4(+) regulatory T cells (Tregs) are essential for controlling immune responses and preventing autoimmunity. Their development requires regulation of gene…”
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