Search Results - "Garcia‐Pelagio, Karla P."

Disruption of action potential and calcium signaling properties in malformed myofibers from dystrophin‐deficient mice by Hernández‐Ochoa, Erick O., Pratt, Stephen J. P., Garcia‐Pelagio, Karla P., Schneider, Martin F., Lovering, Richard M.

“…Duchenne muscular dystrophy (DMD), the most common and severe muscular dystrophy, is caused by the absence of dystrophin. Muscle weakness and fragility (i.e.,…”
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Biomechanical Properties of the Sarcolemma and Costameres of Skeletal Muscle Lacking Desmin by Garcia-Pelagio, Karla P., Bloch, Robert J.

“…Intermediate filaments (IFs), composed primarily by desmin and keratins, link the myofibrils to each other, to intracellular organelles, and to the sarcolemma…”
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Effects of myofiber isolation technique on sarcolemma biomechanics by Garcia-Pelagio, Karla P, Pratt, Stephen JP, Lovering, Richard M

“…Isolated myofibers are commonly used to understand the function of skeletal muscle . This can involve single isolated myofibers obtained from dissection or…”
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Myopathic changes in murine skeletal muscle lacking synemin by García-Pelagio, Karla P, Muriel, Joaquin, O'Neill, Andrea, Desmond, Patrick F, Lovering, Richard M, Lund, Linda, Bond, Meredith, Bloch, Robert J

“…Diseases of striated muscle linked to intermediate filament (IF) proteins are associated with defects in the organization of the contractile apparatus and its…”
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Women’s Lives Matter—The Critical Need for Women to Prioritize Optimal Physical Activity to Reduce COVID-19 Illness Risk and Severity by Garcia-Pelagio, Karla P., Hew-Butler, Tamara, Fahlman, Mariane M., Roche, Joseph A.

“…Physical activity (PA) is beneficial for the health and wellness of individuals and societies. During an infectious disease pandemic, such as the one caused by…”
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Deficiency of the intermediate filament synemin reduces bone mass in vivo by Moorer, Megan C, Buo, Atum M, Garcia-Pelagio, Karla P, Stains, Joseph P, Bloch, Robert J

“…While the type IV intermediate filament protein, synemin, has been shown to play a role in striated muscle and neuronal tissue, its presence and function have…”
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Absence of synemin in mice causes structural and functional abnormalities in heart by García-Pelagio, Karla P., Chen, Ling, Joca, Humberto C., Ward, Christopher, Jonathan Lederer, W., Bloch, Robert J.

“…Cardiomyopathies have been linked to changes in structural proteins, including intermediate filament (IF) proteins located in the cytoskeleton. IFs associate…”
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Infrared thermography and computed tomography imaging for hind limb study after immobilization-induced disuse atrophy by Berenice Martínez-Gutiérrez, Berenice Martínez-Gutiérrez, Karla P. García-Pelagio, Karla P. García-Pelagio

“…Immobilization for treatment after an injury can lead to disuse atrophy, resulting in reduced functionality and strength of the immobilized limb. In our study,…”
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Mechanobiology in Muscle Fibers of Dystrophic Mice by Mendoza-Padilla, Roberto, Bloch, Robert, Gonzales-Serratos, Hugo, Garcia-Pelagio, Karla P.

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Deficiency of the intermediate filament syemin causes abnormalities in striated muscle and reduces bone mass by Garcia‐Pelagio, Karla P., Moorer, Megan, Buo, Atum, Chen, Ling, Stain, Joseph, Bloch, Robert

“…Abstract only A large number of diseases ranging from skin disorders, to premature aging, to skeletal and cardiac myopathies are usually associated to…”
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Sarcolemmal Biomechanics and Excitability in Malformed Muscle Fibers of Dystrophic Mice by Garcia-Pelagio, Karla P., Hernández-Ochoa, Erick O., Pratt, Stephen J.P., Twomey, Kathleen, Lovering, Richard M.

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Modeling The Membrane-Costamere-Myofibril Complex from Normal and Desmin or Dystrophin Mice as a Distributed Elastic System by Garcia-Pelagio, Karla P., Santamaria, Ivan, Bloch, Robert J., Ortega, A., Gonzalez-Serratos, H.L.

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