Search Results - "Garcia‐Pagan, Juan C."

Esophageal balloon tamponade versus esophageal stent in controlling acute refractory variceal bleeding: A multicenter randomized, controlled trial by Escorsell, Àngels, Pavel, Oana, Cárdenas, Andrés, Morillas, Rosa, Llop, Elba, Villanueva, Càndid, Garcia‐Pagán, Juan C., Bosch, Jaime

“…Balloon tamponade is recommended only as a “bridge” to definitive therapy in patients with cirrhosis and massive or refractory esophageal variceal bleeding…”
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Idiopathic noncirrhotic portal hypertension by Schouten, Jeoffrey N.L., Garcia‐Pagan, Juan C., Valla, Dominique C., Janssen, Harry L.A.

“…Idiopathic noncirrhotic portal hypertension (INCPH) is characterized by an increased portal venous pressure gradient in the absence of a known cause of liver…”
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Esophageal Stents for Acute Variceal Bleeding: Expanding the Possibilities by Escorsell, Àngels, García-Pagán, Juan C., Bosch, Jaime

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Acute variceal bleeding: risk stratification and management (including TIPS) by Hernández-Gea, Virginia, Berbel, Claudia, Baiges, Anna, García-Pagán, Juan C.

“…Acute variceal bleeding should be suspected in all patients with cirrhosis presenting with upper gastrointestinal bleeding. Vasoactive drugs and prophylactic…”
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Transjugular Intrahepatic Portosystemic Shunt for Acute Variceal Bleeding: A Meta-analysis by Qi, Xingshun, Jia, Jia, Bai, Ming, Guo, Xiaozhong, Su, Chunping, García-Pagán, Juan C, Han, Guohong, Fan, Daiming

“…BACKGROUND AND AIMS:Acute variceal bleeding is the most common lethal complication of liver cirrhosis. A meta-analysis was conducted to compare the outcomes of…”
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Exploring algorithms to select candidates for non-selective beta-blockers in cirrhosis: A post hoc analysis of the PREDESCI trial by Dajti, Elton, Villanueva, Càndid, Berzigotti, Annalisa, Brujats, Anna, Albillos, Agustín, Genescà, Joan, García-Pagán, Juan C., Colecchia, Antonio, Bosch, Jaume, Villanueva, Càndid, Albillos, Agustín, Genescà, Joan, Garcia-Pagan, Juan C., Calleja, José L., Aracil, Carles, Bañares, Rafael, Morillas, Rosa M., Poca, María, Peñas, Beatriz, Augustin, Salvador, Abraldes, Juan G., Alvarado, Edilmar, Torres, Ferran, Bosch, Jaume

“…Whether non-invasive tests (NITs) can accurately select patients with cirrhosis requiring non-selective beta-blockers (NSBBs) for clinically significant portal…”
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Noninvasive Prediction of Clinically Significant Portal Hypertension and Esophageal Varices in Patients With Compensated Liver Cirrhosis by BERZIGOTTI, Annalisa, GILABERT, Rosa, ABRALDES, Juan G, NICOLAU, Carlos, BRU, Concepcion, BOSCH, Jaime, GARCIA-PAGAN, Juan C

“…We aimed to develop a model based on noninvasive variables for the prediction of clinically significant portal hypertension (CSPH) and of esophageal varices…”
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Pre-emptive TIPS for the treatment of bleeding from gastric fundal varices: Results of a randomised controlled trial by Escorsell, Angels, Garcia-Pagán, Juan C., Alvarado-Tapia, Edilmar, Aracil, Carles, Masnou, Helena, Villanueva, Càndid, Bosch, Jaume

“…Bleeding from gastric fundal varices (isolated gastric varices type 1/gastroesophageal varices type 2) represents a major problem because of a high incidence…”
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Changes in Hepatic Venous Pressure Gradient Predict Hepatic Decompensation in Patients Who Achieved Sustained Virologic Response to Interferon‐Free Therapy by Mandorfer, Mattias, Kozbial, Karin, Schwabl, Philipp, Chromy, David, Semmler, Georg, Stättermayer, Albert F., Pinter, Matthias, Hernández‐Gea, Virginia, Fritzer‐Szekeres, Monika, Steindl‐Munda, Petra, Trauner, Michael, Peck‐Radosavljevic, Markus, García‐Pagán, Juan C., Ferenci, Peter, Reiberger, Thomas

“…Background and Aims Sustained virologic response (SVR) to interferon (IFN)‐free therapies ameliorates portal hypertension (PH); however, it remains unclear…”
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Alcohol‐related liver disease phenotype impacts survival after an acute variceal bleeding episode by Villagrasa, Ares, Hernández‐Gea, Virginia, Bataller, Ramon, Giráldez, Álvaro, Procopet, Bogdan, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibañez‐Samaniego, Luis, Albillos, Agustin, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazon, J. M., Castellote, Jose, Rodrigues, Susana, Gluud, Lise L., Ferreira, Carlos N., Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose L., Gronbaek, Henning, Hernández‐Guerra, Manuel, Sassatelli, Romano, Dell'Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Silva‐Junior, Gilberto, Romero‐Gómez, Manuel, Tantau, Marcel, Guardascione, Maria A., Alvarado, Edilmar, Rudler, Marika, Bañares, Rafael, Martinez, Javier, Robic, Marie A., Jansen, Christian, Calleja, Jose L., Nevens, Frederik, Bosch, Jaime, Ventura‐Cots, Meritxell, García‐Pagan, Juan C., Genescà, Joan

“…Background & Aims Alcohol‐related hepatitis (AH) encompasses a high mortality. AH might be a concomitant event in patients with acute variceal bleeding (AVB)…”
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2D shear wave liver elastography by Aixplorer to detect portal hypertension in cirrhosis: An individual patient data meta‐analysis by Thiele, Maja, Hugger, Mie B., Kim, Yongsoo, Rautou, Pierre‐Emmanuel, Elkrief, Laure, Jansen, Christian, Verlinden, Wim, Allegretti, Giulia, Israelsen, Mads, Stefanescu, Horia, Piscaglia, Fabio, García‐Pagán, Juan C., Franque, Sven, Berzigotti, Annalisa, Castera, Laurent, Jeong, Woo K., Trebicka, Jonel, Krag, Aleksander

“…Background & Aims Liver stiffness measured with 2‐dimensional shear wave elastography by Supersonic Imagine (2DSWE‐SSI) is well‐established for fibrosis…”
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Risk of non‐tumoural portal vein thrombosis in patients with HCV‐induced cirrhosis after sustained virological response by Mandorfer, Mattias, Turon, Fanny, Lens, Sabela, Baiges, Anna, García‐Criado, Ángeles, Darnell, Anna, Belmonte, Ernest, Ferrusquía‐Acosta, José, Magaz, Marta, Perez‐Campuzano, Valeria, Olivas, Pol, Bauer, David, Casanovas, Georgina, Torres, Ferran, Mariño, Zoe, Forns, Xavier, Hernández‐Gea, Virginia, García‐Pagán, Juan C.

“…Background & Aims Sustained virological response (SVR) to direct‐acting antivirals ameliorates portal hypertension, improves hepatic function and may reverse…”
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Impact of deep sedation on the accuracy of hepatic and portal venous pressure measurements in patients with cirrhosis by Reverter, Enric, Blasi, Annabel, Abraldes, Juan G., Martínez-Palli, Graciela, Seijo, Susana, Turon, Fanny, Berzigotti, Annalisa, Balust, Jaume, Bosch, Jaume, García-Pagán, Juan C.

“…Background & Aims Measurement of the hepatic venous pressure gradient (HVPG) offers valuable prognostic information in patients with cirrhosis. In specific…”
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Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis by Reverter, Enric, Lozano, Juan J., Alonso, Cristina, Berzigotti, Annalisa, Seijo, Susana, Turon, Fanny, Baiges, Anna, Martínez‐Chantar, Mari L., Mato, José M., Martínez‐Arranz, Ibon, La Mura, Vincenzo, Hernández‐Gea, Virginia, Bosch, Jaume, García‐Pagán, Juan C.

“…Background In cirrhosis, a decrease in hepatic venous pressure gradient (HVPG) > 10% after acute iv propranolol (HVPG response) is associated with a lower risk…”
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Circulating levels of butyrate are inversely related to portal hypertension, endotoxemia, and systemic inflammation in patients with cirrhosis by Juanola, Oriol, Ferrusquía-Acosta, José, García-Villalba, Rocío, Zapater, Pedro, Magaz, Marta, Marín, Alicia, Olivas, Pol, Baiges, Anna, Bellot, Pablo, Turon, Fanny, Hernández-Gea, Virginia, González-Navajas, José M., Tomás-Barberán, Francisco A., García-Pagán, Juan C., Francés, Rubén

“…ABSTRACT Short‐chain fatty acids (SCFAs) are gut microbiota‐derived products that participate in maintaining the gut barrier integrity and host's immune…”
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Role of gap junctions modulating hepatic vascular tone in cirrhosis by Hernández-Guerra, Manuel, González-Méndez, Yanira, de Ganzo, Zaida A., Salido, Eduardo, García-Pagán, Juan C., Abrante, Beatriz, Malagón, Antonio M., Bosch, Jaime, Quintero, Enrique

“…Background & Aims Gap junctions are formed by connexins (Cx), a family of proteins that couple endothelial and smooth muscle cells in systemic vessels. In this…”
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Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised individual patient data meta-analysis by Nicoară-Farcău, Oana, Han, Guohong, Rudler, Marika, Angrisani, Debora, Monescillo, Alberto, Torres, Ferran, Casanovas, Georgina, Bosch, Jaime, Lv, Yong, Dunne, Philip D J, Hayes, Peter C, Thabut, Dominique, Fan, Daiming, Hernández-Gea, Virginia, García-Pagán, Juan C

“…A previous individual patient data meta-analysis (IPD-MA) showed that compared with drugs+endoscopy, the placement of transjugular portosystemic shunt within…”
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Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with cirrhosis by Bellis, Lia, Berzigotti, Annalisa, Abraldes, Juan G., Moitinho, Eduardo, Garcı́a-Pagán, Juan C., Bosch, Jaime, Rodés, Juan

“…Postprandial hyperemia is associated with a significant increase in portal pressure in cirrhosis, which may contribute to progressive dilation and rupture of…”
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Systemic hemodynamics, vasoactive systems, and plasma volume in patients with severe Budd-Chiari syndrome by HERNANDEZ-GUERRA, Manuel, LOPEZ, Eric, BELLOT, Pablo, PIERA, Carlos, TURNES, Juan, ABRALDES, Juan G, BOSCH, Jaime, GARCIA-PAGAN, Juan C

“…Budd-Chiari syndrome (BCS) causes postsinusoidal portal hypertension, which leads to complications similar to those observed in cirrhosis. However, no studies…”
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Ascorbic acid improves the intrahepatic endothelial dysfunction of patients with cirrhosis and portal hypertension by HERNANDEZ-GUERRA, Manuel, GARCIA-PAGAN, Juan C, TURNES, Juan, BELLOT, Pablo, DEULOFEU, Ramon, ABRALDES, Juan G, BOSCH, Jaime

“…Patients with cirrhosis show intrahepatic endothelial dysfunction, characterized by an impaired flow-dependent vasorelaxation. This alteration is responsible…”
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