Search Results - "Garcia‐Gorro, Clara"
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Gray Matter Vulnerabilities Predict Longitudinal Development of Apathy in Huntington's Disease
Published in Movement disorders (01-09-2021)“…Background Apathy, a common neuropsychiatric disturbance in Huntington's disease (HD), is subserved by a complex neurobiological network. However, no study has…”
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Disentangling the neurobiological bases of temporal impulsivity in Huntington's disease
Published in Brain and behavior (01-03-2024)“…Background Despite its impact on daily life, impulsivity in Huntington's disease (HD) is understudied as a neuropsychiatric symptom. Our aim is to characterize…”
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Reduced striato‐cortical and inhibitory transcallosal connectivity in the motor circuit of Huntington's disease patients
Published in Human brain mapping (01-01-2018)“…Huntington's disease (HD) is a neurodegenerative disorder which is primarily associated with striatal degeneration. However, the alterations in connectivity of…”
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A systematic linguistic profile of spontaneous narrative speech in pre-symptomatic and early stage Huntington's disease
Published in Cortex (01-03-2018)“…Cognitive decline accompanying the clinically more salient motor symptoms of Huntington's disease (HD) has been widely noted and can precede motor symptoms…”
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5
White matter cortico-striatal tracts predict apathy subtypes in Huntington's disease
Published in NeuroImage clinical (01-01-2019)“…Apathy is the neuropsychiatric syndrome that correlates most highly with Huntington's disease progression, and, like early patterns of neurodegeneration, is…”
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Specific patterns of brain alterations underlie distinct clinical profiles in Huntington's disease
Published in NeuroImage clinical (01-01-2019)“…Huntington's disease (HD) is a genetic neurodegenerative disease which involves a triad of motor, cognitive and psychiatric disturbances. However, there is…”
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Neuroimaging as a tool to study the sources of phenotypic heterogeneity in Huntington's disease
Published in Current opinion in neurology (01-08-2017)“…Huntington's disease is a neurodegenerative disorder characterized by a triad of motor, cognitive and psychiatric disturbances. There is great variability…”
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E06 Temporo-spatial structural characterization of deep white matter tracts across the spectrum of Huntington’s disease
Published in Journal of neurology, neurosurgery and psychiatry (12-09-2022)“…BackgroundAlthough white matter (WM) abnormalities and subcortical iron accumulation are causal factors of neurodegeneration in Huntington’s disease (HD),…”
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Changes in Gray Matter Volume Predict Longitudinal Development of Apathy in Huntington’s Disease (1488)
Published in Neurology (14-04-2020)“…Abstract only…”
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10
An active cognitive lifestyle as a potential neuroprotective factor in Huntington's disease
Published in Neuropsychologia (01-01-2019)“…A cognitive stimulating lifestyle has been observed to confer cognitive benefits in multiple neurodegenerative diseases. However, the underlying…”
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F24 Unsupervised clustering reveals longitudinal psychiatric signatures in HD
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2021)“…BackgroundWhile Huntington’s disease (HD) is diagnosed by motor onset, psychiatric disturbances may present years prior to formal diagnosis, bearing a…”
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E08 Tracking the neurodegeneration pattern of the anterior thalamic radiations in HD: a focus on brain iron, white matter integrity and metabolites
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2021)“…BackgroundHD is a suitable model to monitor the whole neurodegeneration process. Huntington’s disease (HD) affects primarily the striatum, but loss of white…”
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13
Delineating apathy profiles in Huntington's disease with the short-Lille Apathy Rating Scale
Published in Parkinsonism & related disorders (01-12-2022)“…Apathy, a prevalent feature in neurological disorders including Huntington's disease (HD), is characterized by a reduction in goal-directed behavior across…”
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14
A systematic linguistic profile of spontaneous narrative speech in pre-symptomatic and early stage Huntington's disease
Published in Cortex (2018)“…Cognitive decline accompanying the clinically more salient motor symptoms of Huntington's disease (HD) has been widely noted and can precede motor symptoms…”
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F13 Deviant language patterns in huntington’s spontaneous speech
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2016)“…BackgroundLanguage has been shown to be affected in Huntington’s disease (HD) in several experimental tasks, independently of cognitive disabilities and since…”
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D23 The effect of cognitive reserve on age of onset and executive functions in huntington’s disease and its neurobiological bases
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2016)“…BackgroundAlthough age of onset of Huntington’s disease (HD) is mainly determined by the size of the CAG repeat expansion, other factors may play a role. One…”
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D24 Intact emotional impulsivity in huntington’s disease despite altered structural connectivity in the uncinate fasciculus
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2016)“…BackgroundImpulsivity in Huntington’s disease (HD) patients has been understudied despite its clear impact in daily life. Although it is known that there are…”
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18
A systematic linguistic profile of spontaneous narrative speech in pre-symptomatic and early stage Huntington's disease
Published in Cortex (01-08-2018)“…Cognitive decline accompanying the clinically more salient motor symptoms of Hunting- ton's disease (HD) has been widely noted and can precede motor symptoms…”
Get full text
Journal Article -
19
A systematic linguistic profile of spontaneous narrative speech in pre-symptomatic and early stage Huntington's disease
Published in Cortex (01-08-2018)“…Cognitive decline accompanying the clinically more salient motor symptoms of Hunting- ton's disease (HD) has been widely noted and can precede motor symptoms…”
Get full text
Journal Article -
20
A systematic linguistic profile of spontaneous narrative speech in pre-symptomatic and early stage Huntington's disease
Published in Cortex (01-08-2018)“…Cognitive decline accompanying the clinically more salient motor symptoms of Hunting- ton's disease (HD) has been widely noted and can precede motor symptoms…”
Get full text
Journal Article